Pyrazolo[1,5-a]pyridine-3-sulfonamide, 6-chloro-N-[6-(2,2-difluoroethoxy)-5-fluoro-2-methoxy-3-pyridinyl]-

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Pyrazolo[1,5-a]pyridine-3-sulfonamide, 6-chloro-N-[6-(2,2-difluoroethoxy)-5-fluoro-2-methoxy-3-pyridinyl]- Basic information
Product Name:Pyrazolo[1,5-a]pyridine-3-sulfonamide, 6-chloro-N-[6-(2,2-difluoroethoxy)-5-fluoro-2-methoxy-3-pyridinyl]-
Synonyms:Pyrazolo[1,5-a]pyridine-3-sulfonamide, 6-chloro-N-[6-(2,2-difluoroethoxy)-5-fluoro-2-methoxy-3-pyridinyl]-;GPR17 modulator-1
CAS:3039853-91-0
MF:C15H12ClF3N4O4S
MW:436.79
EINECS:
Product Categories:
Mol File:3039853-91-0.mol
Pyrazolo[1,5-a]pyridine-3-sulfonamide, 6-chloro-N-[6-(2,2-difluoroethoxy)-5-fluoro-2-methoxy-3-pyridinyl]- Structure
Pyrazolo[1,5-a]pyridine-3-sulfonamide, 6-chloro-N-[6-(2,2-difluoroethoxy)-5-fluoro-2-methoxy-3-pyridinyl]- Chemical Properties
density 1.65±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka-6.39±0.40(predicted)
Safety Information
MSDS Information
Pyrazolo[1,5-a]pyridine-3-sulfonamide, 6-chloro-N-[6-(2,2-difluoroethoxy)-5-fluoro-2-methoxy-3-pyridinyl]- Usage And Synthesis
UsesGPR17 modulator-1 (Compound 2-046) is a modulator for G protein-coupled receptor 17 GPR17, with an IC50<10 nM for hGPR17 in CHO. GPR17 modulator-1 exhibits moderate pharmacokinetic characteristics in mice. GPR17 modulator-1 ix blood-brain barrier (BBB) permeable[1].
References[1] Han X, et al., Gpr17 modulators and uses thereof. WO2024104462.
Pyrazolo[1,5-a]pyridine-3-sulfonamide, 6-chloro-N-[6-(2,2-difluoroethoxy)-5-fluoro-2-methoxy-3-pyridinyl]- Preparation Products And Raw materials
Tag:Pyrazolo[1,5-a]pyridine-3-sulfonamide, 6-chloro-N-[6-(2,2-difluoroethoxy)-5-fluoro-2-methoxy-3-pyridinyl]-(3039853-91-0) Related Product Information
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