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5-chloro-2-methoxy-phenol

CAS No.
3743-23-5
Chemical Name:
5-chloro-2-methoxy-phenol
Synonyms
5-Chloroguaiacol;5-chloro-2-methoxyphenole;5-chloro-2-methoxy-phenol;2-Hydroxy-4-chloroanisole;Phenol, 5-chloro-2-methoxy-;4-Chloro-2-hydroxyanisole, 4-Chloro-2-hydroxyphenyl methyl ether
CBNumber:
CB61457951
Molecular Formula:
C7H7ClO2
Molecular Weight:
158.58
MDL Number:
MFCD11100133
MOL File:
3743-23-5.mol
MSDS File:
SDS
Last updated:2026-05-28 01:17:16

5-chloro-2-methoxy-phenol Properties

Melting point 161-163.5℃
Boiling point 237-239℃ (760 Torr)
Density 1.280±0.06 g/cm3(Predicted)
storage temp. 2-8°C
form crystalline powder
pka 9.01±0.10(Predicted)
color Creamy to faint tan

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
Risk Statements  41
Safety Statements  26-39
HS Code  2907290090

5-chloro-2-methoxy-phenol price More Price(45)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth DAA74323 5-Chloro-2-methoxyphenol 3743-23-5 5g $472 2026-06-04 Buy
Biosynth DAA74323 5-Chloro-2-methoxyphenol 3743-23-5 50g $2360 2026-06-04 Buy
Activate Scientific AS29680 5-Chloro-2-methoxyphenol 97% 3743-23-5 1g $89 2026-06-04 Buy
Activate Scientific AS29680 5-Chloro-2-methoxyphenol 97% 3743-23-5 5g $220 2026-06-04 Buy
aablocks AA00BZFL 5-Chloro-2-methoxyphenol ≥97% 3743-23-5 100mg $14 2026-05-28 Buy
Product number Packaging Price Buy
DAA74323 5g $472 Buy
DAA74323 50g $2360 Buy
AS29680 1g $89 Buy
AS29680 5g $220 Buy
AA00BZFL 100mg $14 Buy

5-chloro-2-methoxy-phenol Chemical Properties,Uses,Production

Synthesis

5-Chloro-2-methoxyphenylboronic acid

89694-48-4

5-chloro-2-methoxy-phenol

3743-23-5

General procedure for the synthesis of 5-chloro-2-methoxyphenylboronic acid as a raw material for the synthesis of 5-chloro-2-methoxyphenol: 5-chloro-2-methoxyphenylboronic acid (5.0 g, 26.82 mmol) was dissolved in water (20 mL) at room temperature, followed by the addition of sodium hydroxide pellets (1.6 g, 40.23 mmol). The reaction mixture was stirred for 20 min and then sodium bicarbonate solution (20 mL) was added, followed by acetone (50 mL) and EDTA (0.8 g, 2.68 mmol). The mixture was cooled to 0°C and Oxone (18.0 g, 29.51 mmol) was added. The mixture was slowly warmed to room temperature over 24 h. Sodium sulfite (1.20 g) was subsequently added, followed by concentrated hydrochloric acid (15 mL) and EtOAc (30 mL). The organic and aqueous phases were separated and the aqueous phase was re-extracted with EtOAc (30 mL). The organic phases were combined, dried with magnesium sulfate, and concentrated under reduced pressure to remove the solvent to afford the target product 5-chloro-2-methoxyphenol in a yield of 4.0 g (95% yield). The product was characterized by 1H NMR (400 MHz, CDCl3): δ 3.90 (3H, s), 5.60 (1H, s), 6.80 (1H, d), 6.90 (1H, d), 6.95 (1H, s).

References

[1] Patent: WO2006/67587, 2006, A2. Location in patent: Page/Page column 22; 23
[2] Patent: US6207662, 2001, B1

5-chloro-2-methoxy-phenol Preparation Products And Raw materials

Global( 74)Suppliers
Supplier Tel Email Country ProdList Advantage
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57
Atop-Pharma (Shanghai) Technology Co., Ltd. +86 (21) 5196-9732 China 996 57
Shanghai T&W Pharmaceutical Co., Ltd. +86 21 61551611 China 9874 58
Nanjing Norris-Pharm Technology Co., Ltd 13901585132 sales@norris-pharm.com China 8869 55
Shanghai Jian Chao Chemical Technology Co., Ltd. 150-2103-5486 18017383231 983544897@qq.com China 9336 55
SynAsst Chemical. 021-60343070 China 12731 55
Shanghai Run-Biotech Co., Ltd. 021-57171705 13817537615 sales@run-biotech.com China 2283 58
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66028182 17714375163 yftan@aikonchem.com China 16674 50

View Lastest Price from 5-chloro-2-methoxy-phenol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Hydroxy-4-chloroanisole pictures 2024-07-14 2-Hydroxy-4-chloroanisole
3743-23-5
$1.00 1KG 99% 20t Shaanxi Dideu Medichem Co. Ltd
5-chloro-2-methoxy-phenol pictures 2021-07-13 5-chloro-2-methoxy-phenol
3743-23-5
$10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
5-chloro-2-methoxy-phenol pictures 2021-07-10 5-chloro-2-methoxy-phenol
3743-23-5
$10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd

5-chloro-2-methoxy-phenol Spectrum

5-chloro-2-methoxy-phenol 4-Chloro-2-hydroxyanisole, 4-Chloro-2-hydroxyphenyl methyl ether 2-Hydroxy-4-chloroanisole 5-Chloroguaiacol 5-chloro-2-methoxyphenole Phenol, 5-chloro-2-methoxy- 3743-23-5 Phenyls & Phenyl-Het Phenyls & Phenyl-Het