2-methoxy-4-methyl-benzaldehyde
- CAS No.
- 57415-35-7
- Chemical Name:
- 2-methoxy-4-methyl-benzaldehyde
- Synonyms
- 4-Methyl-6-methoxybenzaldehyde;2-methoxy-4-methyl-benzaldehyde;Benzaldehyde, 2-methoxy-4-methyl-;2-methoxy-4-methylbenzenemethylaldehyde;2-methoxy-4-methylbenzaldehyde(SALTDATA: FREE)
- CBNumber:
- CB61458781
- Molecular Formula:
- C9H10O2
- Molecular Weight:
- 150.17
- MDL Number:
- MFCD06248007
- MOL File:
- 57415-35-7.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H315-H335 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 |
| HazardClass | IRRITANT |
| HS Code | 2913000090 |
2-methoxy-4-methyl-benzaldehyde price More Price(44)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 418577 | 2-Methoxy-4-methylbenzaldehyde | 57415-35-7 | 100mg | $326 | 2026-06-03 | Buy |
| Usbiological | 418577 | 2-Methoxy-4-methylbenzaldehyde | 57415-35-7 | 250mg | $475 | 2026-06-03 | Buy |
| AstaTech | SC3771 | 2-METHOXY-4-METHYLBENZALDEHYDE 95% | 57415-35-7 | 1G | $19 | 2026-04-30 | Buy |
| AstaTech | SC3771 | 2-METHOXY-4-METHYLBENZALDEHYDE 95% | 57415-35-7 | 5G | $63 | 2026-04-30 | Buy |
| AstaTech | SC3771 | 2-METHOXY-4-METHYLBENZALDEHYDE 95% | 57415-35-7 | 25G | $294 | 2026-04-30 | Buy |
2-methoxy-4-methyl-benzaldehyde Chemical Properties,Uses,Production
Uses
2-Methoxy-4-methylbenzaldehyde acts as a reagent in the synthesis of [3,2-d]pyrimidine derivatives as week as in the synthesis of tachykinin NK2 receptor antagonists which may be used in the treatment of IBS.
Synthesis Reference(s)
Journal of Medicinal Chemistry, 35, p. 734, 1992 DOI: 10.1021/jm00082a014
Synthesis
698-27-1
74-88-4
57415-35-7
GENERAL METHODS: Potassium carbonate (K2CO3, 35 mg, 0.25 mmol) was added to a solution of anhydrous N,N-dimethylformamide (DMF, 6.0 mL) of 2-hydroxy-4-methylbenzaldehyde (34 mg, 0.25 mmol) and the mixture was stirred at room temperature for 30 min. Subsequently, iodomethane (CH3I, 30 μL, 68 mg, 0.5 mmol) was added and the reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, distilled water was added to terminate the reaction and the aqueous phase was extracted three times with ethyl acetate (EtOAc). The organic phases were combined and dried over anhydrous magnesium sulfate (MgSO4) and subsequently concentrated under reduced pressure. The residue was purified by silica gel column chromatography.
References
[1] Beilstein Journal of Organic Chemistry, 2018, vol. 14, p. 734 - 746
[2] Synthesis (Germany), 2017, vol. 49, # 1,
2-methoxy-4-methyl-benzaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
| Shanghai Aobo pharmaceutical Technology Co., Ltd | 86-21-51320499 | aobo@aobopharm.com | China | 297 | 57 |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| Tianjin Ji Ping Jia Chemical Co., Ltd. | 18622448868 | jpjchem@163.com | China | 489 | 62 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Accela ChemBio Inc. | +1(858) 699-3322 | marketing@accelachem.com | United States | 6022 | 65 |
| Zhengzhou Alfachem Co., Ltd. | 0371-53765687 18937137882 | 3969243885@qq.com | China | 7734 | 55 |
