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Benzamide, N-(2-hydroxyethyl)-2-methyl-3-[[4-[[3-(trifluoromethyl)phenyl]methyl]-2-pyridinyl]amino]-

CAS No.
2767348-36-5
Chemical Name:
Benzamide, N-(2-hydroxyethyl)-2-methyl-3-[[4-[[3-(trifluoromethyl)phenyl]methyl]-2-pyridinyl]amino]-
Synonyms
PW0729;Benzamide, N-(2-hydroxyethyl)-2-methyl-3-[[4-[[3-(trifluoromethyl)phenyl]methyl]-2-pyridinyl]amino]-
CBNumber:
CB614685637
Molecular Formula:
C23H22F3N3O2
Molecular Weight:
429.44
MDL Number:
MOL File:
2767348-36-5.mol
MSDS File:
SDS
Last updated:2025-04-17 18:22:24

Benzamide, N-(2-hydroxyethyl)-2-methyl-3-[[4-[[3-(trifluoromethyl)phenyl]methyl]-2-pyridinyl]amino]- Properties

Boiling point 557.8±50.0 °C(predicted)
Density 1.292±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka 14.23±0.46(predicted)

Benzamide, N-(2-hydroxyethyl)-2-methyl-3-[[4-[[3-(trifluoromethyl)phenyl]methyl]-2-pyridinyl]amino]- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-1099002 PW0729 99.55% 2767348-36-5 5mg $372 2026-06-04 Buy
ChemScene CS-1099002 PW0729 99.55% 2767348-36-5 10mg $596 2026-06-04 Buy
ChemScene CS-1099002 PW0729 99.55% 2767348-36-5 25mg $1192 2026-06-04 Buy
ChemScene CS-1099002 PW0729 99.55% 2767348-36-5 50mg $1896 2026-06-04 Buy
Arctom HY-163671 PW0729 99.55% 2767348-36-5 5mg $408 2026-05-26 Buy
Product number Packaging Price Buy
CS-1099002 5mg $372 Buy
CS-1099002 10mg $596 Buy
CS-1099002 25mg $1192 Buy
CS-1099002 50mg $1896 Buy
HY-163671 5mg $408 Buy

Benzamide, N-(2-hydroxyethyl)-2-methyl-3-[[4-[[3-(trifluoromethyl)phenyl]methyl]-2-pyridinyl]amino]- Chemical Properties, Uses, Production

Uses

PW0729 (compound 15b) is an orphan GPR52 agonist with potential applications in GPR52 activation, signaling bias, and neuropsychiatric and neurological disorders. The brain exposure characteristics of PW0729 need to be further optimized[1].

References

[1] Murphy R E, Wang P, Ali S, et al. Discovery of 3-((4-Benzylpyridin-2-yl) amino) benzamides as Potent GPR52 G Protein-Biased Agonists[J]. Journal of Medicinal Chemistry, 2024.

Benzamide, N-(2-hydroxyethyl)-2-methyl-3-[[4-[[3-(trifluoromethyl)phenyl]methyl]-2-pyridinyl]amino]- Preparation Products And Raw materials

Raw materials

Preparation Products

Benzamide, N-(2-hydroxyethyl)-2-methyl-3-[[4-[[3-(trifluoromethyl)phenyl]methyl]-2-pyridinyl]amino]- Suppliers

Global Suppliers ( 2)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Supplier Advantage
TargetMol Chemicals Inc. 58
Benzamide, N-(2-hydroxyethyl)-2-methyl-3-[[4-[[3-(trifluoromethyl)phenyl]methyl]-2-pyridinyl]amino]- PW0729 2767348-36-5