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GSK3335103

CAS No.
1893340-21-0
Chemical Name:
GSK3335103
Synonyms
GSK3335103;1-Pyrrolidinebutanoic acid, 3-fluoro-β-[3-(2-methoxyethoxy)phenyl]-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]-, (βS,3S)-
CBNumber:
CB614907533
Molecular Formula:
C27H36FN3O4
Molecular Weight:
485.59
MDL Number:
MOL File:
1893340-21-0.mol
Last updated:2025-05-19 13:47:16

GSK3335103 Properties

Boiling point 687.132±55.00 °C(Press: 760.00 Torr)(predicted)
Density 1.252±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka 4.274±0.10(predicted)

GSK3335103 Chemical Properties, Uses, Production

Uses

GSK3335103 is an orally active, non-peptide αvβ6 integrin inhibitor (pIC50=8). GSK3335103 can be used in the study of pulmonary fibrosis[1].

References

[1] Procopiou P A, et al. Discovery and Development of Highly Potent and Orally Bioavailable Nonpeptidic αvβ6 Integrin Inhibitors[J]. Journal of Medicinal Chemistry, 2024. DOI:10.1021/acs.jmedchem.4c01430

GSK3335103 Preparation Products And Raw materials

Raw materials

Preparation Products

GSK3335103 Suppliers

Global Suppliers ( 1)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Supplier Advantage
TargetMol Chemicals Inc. 58
GSK3335103 1-Pyrrolidinebutanoic acid, 3-fluoro-β-[3-(2-methoxyethoxy)phenyl]-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]-, (βS,3S)- 1893340-21-0