GP130-IN-1
- CAS No.
- 2955243-69-1
- Chemical Name:
- GP130-IN-1
- Synonyms
- GP130-IN-1;Methanone, [5-hydroxy-2-(4-hydroxyphenyl)-1H-indol-1-yl](2,3,4,5,6-pentafluorophenyl)-
- CBNumber:
- CB614907780
- Molecular Formula:
- C21H10F5NO3
- Molecular Weight:
- 419.3
- MDL Number:
- MOL File:
- 2955243-69-1.mol
- MSDS File:
- SDS
GP130-IN-1 Chemical Properties, Uses, Production
Uses
GP130-IN-1 (compound 49) is a potent GP130 inhibitor with significant in vitro antitumor activity and higher selectivity than Bazedoxifene (HY-A0031). GP130-IN-1 induces ultrastructural changes in cells, causing cell cycle arrest in the G0/G1 phase in a time-dependent manner and triggering apoptosis and autophagy. GP130-IN-1 can be used in the study of triple-negative breast cancer[1].
References
[1] Wu P, et al. Structurally diverse design and synthesis of novel 2-phenylindole amide derivatives with anti-canine breast cancer activity[J]. Bioorganic Chemistry, 2024: 107788. DOI:10.1016/j.bioorg.2024.107788
GP130-IN-1 Preparation Products And Raw materials
Raw materials
Preparation Products
GP130-IN-1 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
