6-Nitro-isoindolin-1-one
- CAS No.
- 110568-64-4
- Chemical Name:
- 6-Nitro-isoindolin-1-one
- Synonyms
- 6-Nitro-1-isoindolinone;6-Nitroisoindoline-1-one;6-Nitro-isoindolin-1-one;Benzene,1,5-bis(decyloxy)-;6-Nitro-2,3-dihydro-isoindol-1-one;6-nitro-2,3-dihydro-1H-isoindol-1-one;1H-Isoindol-1-one, 2,3-dihydro-6-nitro-
- CBNumber:
- CB61560242
- Molecular Formula:
- C8H6N2O3
- Molecular Weight:
- 178.14
- MDL Number:
- MFCD03093931
- MOL File:
- 110568-64-4.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2933790090 |
6-Nitro-isoindolin-1-one price More Price(49)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR305291 | 6-Nitro-2,3-dihydro-1H-isoindol-1-one ≥95% | 110568-64-4 | 250mg | $21 | 2026-06-04 | Buy |
| Matrix Scientific | 102479 | 6-Nitro-2,3-dihydro-1H-isoindol-1-one | 110568-64-4 | 250.00mg | $25 | 2026-05-18 | Buy |
| Matrix Scientific | 102479 | 6-Nitro-2,3-dihydro-1H-isoindol-1-one | 110568-64-4 | 1.00g | $60 | 2026-05-18 | Buy |
| Matrix Scientific | 102479 | 6-Nitro-2,3-dihydro-1H-isoindol-1-one | 110568-64-4 | 5.00g | $153 | 2026-05-18 | Buy |
| Synthonix | N14847 | 6-Nitroisoindolin-1-one 95+% | 110568-64-4 | 1g | $71 | 2026-05-06 | Buy |
6-Nitro-isoindolin-1-one Chemical Properties, Uses, Production
Uses
6-Nitroisoindoline-1-one is a heterocyclic derivative that can be used as a pharmaceutical intermediate. It exists in a variety of natural products and pharmaceutical molecules and has extremely high biological activity.
Synthesis
133446-99-8
110568-64-4
General procedure for the synthesis of 6-nitro-isoindolin-1-one from methyl 2-(bromomethyl)-4-nitrobenzoate: Methyl 2-(bromomethyl)-4-nitrobenzoate (250 mg, 0.92 mmol) was added to a methanolic solution of saturated ammonia (5 mL) and stirred for 2 hr at room temperature, and completion of the reaction was monitored by thin layer chromatography (TLC). The solvent was removed by distillation under reduced pressure and ethyl acetate (7 mL) was added to the residue and sonicated for 3 min, followed by placement in a refrigerator at -20 °C for 3 min to promote crystallization. After precipitating a large amount of solid, the product was collected by filtration and dried under high vacuum to give 150 mg of a pale yellow solid in 92% yield.
References
[1] Patent: CN103804358, 2016, B. Location in patent: Paragraph 0123
[2] Patent: WO2006/17443, 2006, A2. Location in patent: Page/Page column 155
[3] Patent: WO2012/92880, 2012, A1. Location in patent: Page/Page column 57
[4] Patent: WO2015/81891, 2015, A1. Location in patent: Page/Page column 138; 139
[5] Patent: US9138427, 2015, B2. Location in patent: Page/Page column 287
6-Nitro-isoindolin-1-one Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd. | 21-57721279 18121011378 | sales@shydchem.com.cn | China | 998 | 56 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. | 17702719238 | sales@sun-shinechem.com | China | 1205 | 64 |
| Nanjing Vital Chemical Co., Ltd. | Please Send Email 18652950785 | chemweiao@163.com | China | 4368 | 65 |
| Sphinx Scientific Laboratory (Tianjin) Co., Ltd. | 022-66211289-843 13672102692 | contact@sphinxpharm.com | China | 361 | 62 |
| Heterochem | 027-88041443 13072715837 | sales@hetero-chem.com | China | 695 | 58 |
| Acorn PharmaTech Co., Ltd. | 025-58395930 | sales@acornpharma.com | China | 982 | 60 |
| Anhui Shite Pharmaceutical Technology Co., LTD | 086-21-50829787 13621628489 | sales1@stepuppharm.com | China | 253 | 55 |
| T&W GROUP | 021-61551611 13296011611 | contact@trustwe.com | China | 9884 | 58 |
View Latest Price from 6-Nitro-isoindolin-1-one manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-12-26 | 6-NITRO-ISOINDOLIN-1-ONE
110568-64-4
|
$6.60 | 500g | 98% | 1kg, 50kg, 100kg | Career Henan Chemical Co |
-
- 6-NITRO-ISOINDOLIN-1-ONE
110568-64-4
- $6.60
- 98%
- Career Henan Chemical Co
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