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ChemicalBook >> CAS DataBase List >>(R)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE

(R)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE

(R)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE Structure
(R)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE structure
CAS No.
160695-26-1
Chemical Name:
(R)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE
Synonyms
(R)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE;R-(+)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE;(4R)-4-phenyl-3-propanoyl-oxazolidin-2-one;(R)-4-Phenyl-3-propionyloxazolidin-2-one 95+%;(4R)-4-phenyl-3-propanoyl-1,3-oxazolidin-2-one;(4R)-4-Phenyl-3-Propionyl-1,3-Oxazolidin-2-One;(R)-4-Phenyl-3-propionyl-2-oxazolidinone,99%e.e.;2-Oxazolidinone, 3-(1-oxopropyl)-4-phenyl-, (4R)-;(R)-4-Phenyl-3-propionyl-2-oxazolidinone, ee: 97%
CBNumber:
CB6182605
Molecular Formula:
C12H13NO3
Molecular Weight:
219.24
MDL Number:
MFCD06658224
MOL File:
160695-26-1.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:42
Product description Number Pack Size Price
(R)-4-Phenyl-3-propionyloxazolidin-2-one 8109AA 1g $27
(R)-4-Phenyl-3-propionyloxazolidin-2-one 95+% ee AS48516 1g $41
(R)-4-Phenyl-3-propionyloxazolidin-2-one 95+% OR14532 5g $114
(R)-4-Phenyl-3-propionyloxazolidin-2-one 95+% ee AS48516 5G $122
(R)-4-Phenyl-3-propionyloxazolidin-2-one 4H56-1-R6 5G $125
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(R)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE Properties

Melting point 83.5-84 °C(Solv: hexane (110-54-3); toluene (108-88-3))
Boiling point 393.1±31.0 °C(Predicted)
Density 1.223±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka -3.13±0.40(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi,Xn
Risk Statements  20/21/22-36/37/38
Safety Statements  26-36
HS Code  29349990

(R)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE price More Price(21)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AK Scientific 8109AA (R)-4-Phenyl-3-propionyloxazolidin-2-one 160695-26-1 1g $27 2021-12-16 Buy
Activate Scientific AS48516 (R)-4-Phenyl-3-propionyloxazolidin-2-one 95+% ee 160695-26-1 1g $41 2021-12-16 Buy
Apolloscientific OR14532 (R)-4-Phenyl-3-propionyloxazolidin-2-one 95+% 160695-26-1 5g $114 2021-12-16 Buy
Activate Scientific AS48516 (R)-4-Phenyl-3-propionyloxazolidin-2-one 95+% ee 160695-26-1 5G $122 2021-12-16 Buy
SynQuest Laboratories 4H56-1-R6 (R)-4-Phenyl-3-propionyloxazolidin-2-one 160695-26-1 5G $125 2021-12-16 Buy
Product number Packaging Price Buy
8109AA 1g $27 Buy
AS48516 1g $41 Buy
OR14532 5g $114 Buy
AS48516 5G $122 Buy
4H56-1-R6 5G $125 Buy

(R)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE Chemical Properties,Uses,Production

Synthesis

Propionyl chloride

79-03-8

(R)-(-)-4-Phenyl-2-oxazolidinone

90319-52-1

(R)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE

160695-26-1

1. (R)-4-phenyl-2-oxazolidinone (16.3 g, 1.0 eq.) was dissolved in 180 mL of dichloromethane and cooled to 0 °C in an ice bath. 2. Triethylamine (15.2 g, 1.5 eq.) and 4-dimethylaminopyridine (DMAP) (366 mg, 0.03 eq.) were added sequentially with stirring. 3. Propionyl chloride (9.2 g, 1.0 eq.) was added slowly and dropwise, keeping the reaction temperature at 0 °C and continuing to stir for 1 hour. 4. Upon completion of the reaction, the reaction mixture was diluted with methylene chloride and washed sequentially with water and saturated sodium bicarbonate solution. 5. Separate the organic phase and dry with anhydrous sodium sulfate. 6. The solvent was removed by depressurized evaporation to obtain the crude product. 7. The crude product was purified by column chromatography to afford the target compound R-4-phenyl-3-propionyl-2-oxazolidinone (III-a) (20.1 g, 92% yield).

References

[1] Organic Letters, 2011, vol. 13, # 21, p. 5762 - 5765
[2] Patent: CN105085322, 2017, B. Location in patent: Paragraph 0065; 0066; 0067; 0068
[3] Organic Process Research and Development, 2005, vol. 9, # 6, p. 827 - 829
[4] Advanced Synthesis and Catalysis, 2018, vol. 360, # 5, p. 965 - 971

(R)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE Preparation Products And Raw materials

Raw materials

Propionyl chloride (R)-(-)-4-Phenyl-2-oxazolidinone Propionic-2,3-14C1 acid (8CI) 4-Dimethylaminopyridine Triethylamine
Dichloromethane

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Preparation Products

(R)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE Suppliers

Global( 56)Suppliers
Supplier Tel Email Country ProdList Advantage
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30228 58
HANGZHOU LEAP CHEM CO., LTD. 		+86-571-87711850 market18@leapchem.com China 24597 58
Suzhou ARTK Medchem Co., Ltd. 		+8618118463618 sales1@artkmedchem.com China 39020 58
DAYANG CHEM (HANGZHOU) CO.,LTD 		+86-88938639 +86-17705817739 info@dycnchem.com China 53802 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
J & K SCIENTIFIC LTD. 18210857532; 18210857532 jkinfo@jkchemical.com China 96815 76
Daicel Chiral Technologies (China)CO.,LTD 021-50460086-9 15921403865 han_yajun@dctc.daicel.com China 7440 65
Tianjin Derchemist Science & Technology Co., Ltd. 22-58627059 13920586291 zdcomcon@126.com China 4015 50
Tianjin Chempharmatech Co.,Ltd. 022-66211079 13212288319 sales@chempharmatech.com China 924 55
Supplier Advantage
Alchem Pharmtech,Inc. 		58
Career Henan Chemica Co 		58
HANGZHOU LEAP CHEM CO., LTD. 		58
Suzhou ARTK Medchem Co., Ltd. 		58
DAYANG CHEM (HANGZHOU) CO.,LTD 		58
Amadis Chemical Company Limited 		58
J & K SCIENTIFIC LTD. 76
Daicel Chiral Technologies (China)CO.,LTD 65
Tianjin Derchemist Science & Technology Co., Ltd. 50
Tianjin Chempharmatech Co.,Ltd. 55

View Lastest Price from (R)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(R)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE pictures 2024-10-22 (R)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE
160695-26-1
 US $1.00 / g 1g 85.0-99.8% 20 tons Career Henan Chemica Co

160695-26-1((R)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE)Related Search:

(4R,5S)-4-METHYL-5-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE (S)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE,S-(-)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE (R)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE (R)-(-)-4-Phenyl-2-oxazolidinone 3-(3R,4-DIMETHYLPENTANOYL)-4R-PHENYLOXAZOLIDIN-2-ONE
(R)-3-ACETYL-4-PHENYL-2-OXAZOLIDINONE

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(R)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE R-(+)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE (4R)-4-phenyl-3-propanoyl-1,3-oxazolidin-2-one (R)-4-Phenyl-3-propionyl-2-oxazolidinone, ee: 97% (R)-4-Phenyl-3-propionyl-2-oxazolidinone,99%e.e. (4R)-4-Phenyl-3-Propionyl-1,3-Oxazolidin-2-One (R)-4-Phenyl-3-propionyloxazolidin-2-one 95+% 2-Oxazolidinone, 3-(1-oxopropyl)-4-phenyl-, (4R)- (4R)-4-phenyl-3-propanoyl-oxazolidin-2-one 160695-26-1 C12H13NO3