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ChemicalBook >> CAS DataBase List >>(R)-4-Phenyl-3-propionyl-2-oxazolidinone

(R)-4-Phenyl-3-propionyl-2-oxazolidinone

(R)-4-Phenyl-3-propionyl-2-oxazolidinone Structure
(R)-4-Phenyl-3-propionyl-2-oxazolidinone structure
CAS No.
160695-26-1
Chemical Name:
(R)-4-Phenyl-3-propionyl-2-oxazolidinone
Synonyms
(R)-4-Phenyl-3-propionyl-2-oxazolidinone;(4R)-4-phenyl-3-propanoyl-oxazolidin-2-one;R-(+)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE;(R)-4-Phenyl-3-propionyloxazolidin-2-one 95+%;(4R)-4-phenyl-3-propanoyl-1,3-oxazolidin-2-one;(4R)-4-Phenyl-3-Propionyl-1,3-Oxazolidin-2-One;(R)-4-Phenyl-3-propionyl-2-oxazolidinone,99%e.e.;2-Oxazolidinone, 3-(1-oxopropyl)-4-phenyl-, (4R)-;(R)-4-Phenyl-3-propionyl-2-oxazolidinone, ee: 97%
CBNumber:
CB6182605
Molecular Formula:
C12H13NO3
Molecular Weight:
219.24
MDL Number:
MFCD06658224
MOL File:
160695-26-1.mol
MSDS File:
SDS
Last updated:2026-09-12 18:54:00
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(R)-4-Phenyl-3-propionyl-2-oxazolidinone Properties

Melting point 83.5-84 °C(Solv: hexane (110-54-3); toluene (108-88-3))
Boiling point 393.1±31.0 °C(Predicted)
Density 1.223±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka -3.13±0.40(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi,Xn
Risk Statements  20/21/22-36/37/38
Safety Statements  26-36
HS Code  29349990

(R)-4-Phenyl-3-propionyl-2-oxazolidinone price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR14532 (R)-4-Phenyl-3-propionyloxazolidin-2-one >97% 160695-26-1 250mg $21 2026-06-04 Buy
Apolloscientific OR14532 (R)-4-Phenyl-3-propionyloxazolidin-2-one >97% 160695-26-1 1g $39 2026-06-04 Buy
Apolloscientific OR14532 (R)-4-Phenyl-3-propionyloxazolidin-2-one >97% 160695-26-1 5g $132 2026-06-04 Buy
Apolloscientific OR14532 (R)-4-Phenyl-3-propionyloxazolidin-2-one >97% 160695-26-1 25g $459 2026-06-04 Buy
Apolloscientific OR14532 (R)-4-Phenyl-3-propionyloxazolidin-2-one >97% 160695-26-1 100g $1734 2026-06-04 Buy
Product number Packaging Price Buy
OR14532 250mg $21 Buy
OR14532 1g $39 Buy
OR14532 5g $132 Buy
OR14532 25g $459 Buy
OR14532 100g $1734 Buy

(R)-4-Phenyl-3-propionyl-2-oxazolidinone Chemical Properties, Uses, Production

Synthesis

Propionyl chloride

79-03-8

(R)-(-)-4-Phenyl-2-oxazolidinone

90319-52-1

(R)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE

160695-26-1

1. (R)-4-phenyl-2-oxazolidinone (16.3 g, 1.0 eq.) was dissolved in 180 mL of dichloromethane and cooled to 0 °C in an ice bath. 2. Triethylamine (15.2 g, 1.5 eq.) and 4-dimethylaminopyridine (DMAP) (366 mg, 0.03 eq.) were added sequentially with stirring. 3. Propionyl chloride (9.2 g, 1.0 eq.) was added slowly and dropwise, keeping the reaction temperature at 0 °C and continuing to stir for 1 hour. 4. Upon completion of the reaction, the reaction mixture was diluted with methylene chloride and washed sequentially with water and saturated sodium bicarbonate solution. 5. Separate the organic phase and dry with anhydrous sodium sulfate. 6. The solvent was removed by depressurized evaporation to obtain the crude product. 7. The crude product was purified by column chromatography to afford the target compound R-4-phenyl-3-propionyl-2-oxazolidinone (III-a) (20.1 g, 92% yield).

References

[1] Organic Letters, 2011, vol. 13, # 21, p. 5762 - 5765
[2] Patent: CN105085322, 2017, B. Location in patent: Paragraph 0065; 0066; 0067; 0068
[3] Organic Process Research and Development, 2005, vol. 9, # 6, p. 827 - 829
[4] Advanced Synthesis and Catalysis, 2018, vol. 360, # 5, p. 965 - 971

(R)-4-Phenyl-3-propionyl-2-oxazolidinone Preparation Products And Raw materials

Raw materials

Propionyl chloride (R)-(-)-4-Phenyl-2-oxazolidinone Propionic-2,3-14C1 acid (8CI) 4-Dimethylaminopyridine Triethylamine
Dichloromethane

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Preparation Products

(R)-4-Phenyl-3-propionyl-2-oxazolidinone Suppliers

Global Suppliers ( 56)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Daicel Chiral Technologies (China)CO.,LTD 021-50460086-9 15921403865 han_yajun@dctc.daicel.com China 7909 65
Tianjin Derchemist Science & Technology Co., Ltd. 22-58627059 13920586291 zdcomcon@126.com China 4094 50
Tianjin Chempharmatech Co.,Ltd. 022-66211079 13212288319 sales@chempharmatech.com China 943 55
Shijiazhuang Lickon PharmaTech Co., Ltd. 031185291771 13832391721 yaofeng2005@163.com China 947 58
Shanghai Leto Pharmatech Co.,Ltd. 86-021-5821 5861; 18016401466 sales@letopharm.com China 235 58
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8000 62
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Greenherbs Science and Technology Development Co., Ltd. 010-61136123 pub02@greenherbs.com.cn China 4045 58
Wuhan FengyaoTonghui Chemical Products Co., Ltd. 027-87466105 15377573527 2678564200@qq.com China 17968 58
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Daicel Chiral Technologies (China)CO.,LTD 65
Tianjin Derchemist Science & Technology Co., Ltd. 50
Tianjin Chempharmatech Co.,Ltd. 55
Shijiazhuang Lickon PharmaTech Co., Ltd. 58
Shanghai Leto Pharmatech Co.,Ltd. 58
ShangHai Biochempartner Co.,Ltd 62
Amadis Chemical Company Limited 58
Greenherbs Science and Technology Development Co., Ltd. 58
Wuhan FengyaoTonghui Chemical Products Co., Ltd. 58

View Latest Price from (R)-4-Phenyl-3-propionyl-2-oxazolidinone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(R)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE pictures 2024-10-22 (R)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE
160695-26-1
 $1.00 1g 85.0-99.8% 20 tons Career Henan Chemica Co

160695-26-1 ((R)-4-Phenyl-3-propionyl-2-oxazolidinone) Related Search:

3-(3R,4-dimethylpentanoyl)-4r-phenyloxazolidin-2-one (R)-3-Acetyl-4-phenyl-2-oxazolidinone (R)-4-Phenyl-3-propionyl-2-oxazolidinone (S)-4-Phenyl-3-propionyl-2-oxazolidinone N-Propionyl-(4S,5R)-4-methyl- 5-phenyl-2-oxazolidinone
(R)-(-)-4-Phenyl-2-oxazolidinone

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R-(+)-4-PHENYL-3-PROPIONYL-2-OXAZOLIDINONE (4R)-4-phenyl-3-propanoyl-1,3-oxazolidin-2-one (R)-4-Phenyl-3-propionyl-2-oxazolidinone, ee: 97% (R)-4-Phenyl-3-propionyl-2-oxazolidinone,99%e.e. (4R)-4-Phenyl-3-Propionyl-1,3-Oxazolidin-2-One (R)-4-Phenyl-3-propionyloxazolidin-2-one 95+% 2-Oxazolidinone, 3-(1-oxopropyl)-4-phenyl-, (4R)- (4R)-4-phenyl-3-propanoyl-oxazolidin-2-one (R)-4-Phenyl-3-propionyl-2-oxazolidinone 160695-26-1 C12H13NO3