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4-(DIMETHYLAMINO)SALICYLALDEHYDE

CAS No.
41602-56-6
Chemical Name:
4-(DIMETHYLAMINO)SALICYLALDEHYDE
Synonyms
4-(DIMETHYLAMINO)SALICYLALDEHYDE;p-(Dimethylamino)salicylaldehyde;4-N,N-Dimethylaminosalicylaldehyde;4-Dimethylamino-2-hydroxybenzaldehyde;Benzaldehyde,4-(diMethylaMino)-2-hydroxy-;4-Dimethylamino-2-hydroxybenzaldehyde 98%;4-(N,N-Dimethylamino)-2-hydroxybenzaldehyde;4-(DiMethylaMino)-2-Hydroxybenzaldehyde Hydrochloride;4-(Dimethylamino)salicylaldehyde, 5-(Dimethylamino)-2-formylphenol
CBNumber:
CB6184816
Molecular Formula:
C9H11NO2
Molecular Weight:
165.19
MDL Number:
MFCD00027419
MOL File:
41602-56-6.mol
Last updated:2025-07-24 18:13:51
Product description Number Pack Size Price
4-(Dimethylamino)-2-hydroxybenzaldehyde min. 98.0 % D6362 1G $126
4-(Dimethylamino)-2-hydroxybenzaldehyde min. 98.0 % D6362 5G $378
4-(Dimethylamino)-2-hydroxybenzaldehyde D460163 50mg $45
4-(Dimethylamino)-2-hydroxybenzaldehyde FD142727 500mg $65
4-(Dimethylamino)-2-hydroxybenzaldehyde FD142727 2g $197
More product size

4-(DIMETHYLAMINO)SALICYLALDEHYDE Properties

Melting point 78-78°C
Boiling point 301.1±27.0 °C(Predicted)
Density 1.201±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 8.27±0.10(Predicted)
Appearance Off-white to yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
HS Code  2922390090

4-(DIMETHYLAMINO)SALICYLALDEHYDE price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical D6362 4-(Dimethylamino)-2-hydroxybenzaldehyde min. 98.0 % 41602-56-6 1G $126 2025-07-31 Buy
TCI Chemical D6362 4-(Dimethylamino)-2-hydroxybenzaldehyde min. 98.0 % 41602-56-6 5G $378 2025-07-31 Buy
TRC D460163 4-(Dimethylamino)-2-hydroxybenzaldehyde 41602-56-6 50mg $45 2021-12-16 Buy
Biosynth Carbosynth FD142727 4-(Dimethylamino)-2-hydroxybenzaldehyde 41602-56-6 500mg $65 2021-12-16 Buy
Biosynth Carbosynth FD142727 4-(Dimethylamino)-2-hydroxybenzaldehyde 41602-56-6 2g $197 2021-12-16 Buy
Product number Packaging Price Buy
D6362 1G $126 Buy
D6362 5G $378 Buy
D460163 50mg $45 Buy
FD142727 500mg $65 Buy
FD142727 2g $197 Buy

4-(DIMETHYLAMINO)SALICYLALDEHYDE Chemical Properties,Uses,Production

Synthesis

N,N-Dimethylformamide

68-12-2

3-Dimethylaminophenol

99-07-0

4-(DIMETHYLAMINO)SALICYLALDEHYDE

41602-56-6

General procedure for the synthesis of 4-(dimethylamino)o-hydroxybenzaldehyde from N,N-dimethylformamide and 3-hydroxy-N,N-dimethylaniline: 13.8 g (0.1 mol) of a mixture of 3-hydroxy-N,N-dimethylaniline and 16.0 g (0.22 mol) of N,N-dimethylformamide was slowly added dropwise at 20-40 °C, followed by the addition of methylsulfonyl chloride (0.125 mol), and the rate of titration was controlled to keep the reaction temperature from exceeding 40 °C. After the titration was completed, the reaction was stopped and the reaction temperature was reduced. After the dropwise addition, the reaction mixture was stirred at 50 to 100 °C for 1.0 hour. After completion of the reaction, the reaction solution was cooled to 30 °C and hydrolyzed by adding an appropriate amount of water. After filtration and washing with a small amount of water, 15.0 g of 4-N,N-dimethyl-2-hydroxybenzaldehyde was obtained with a yield of 90.9% and a purity of 95.5%.

References

[1] Chemistry - An Asian Journal, 2010, vol. 5, # 9, p. 2053 - 2061
[2] Patent: CN104262253, 2017, B. Location in patent: Paragraph 0049; 0050; 0051; 0052
[3] Molecules, 2009, vol. 14, # 12, p. 4838 - 4848
[4] Journal of Molecular Structure, 2018, vol. 1154, p. 373 - 381
[5] Chemical Papers, 2010, vol. 64, # 6, p. 806 - 811

99-07-0
41602-56-6
Synthesis of 4-(DIMETHYLAMINO)SALICYLALDEHYDE from 3-Dimethylaminophenol

4-(DIMETHYLAMINO)SALICYLALDEHYDE Preparation Products And Raw materials

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4-(DIMETHYLAMINO)SALICYLALDEHYDE 4-Dimethylamino-2-hydroxybenzaldehyde 4-(Dimethylamino)salicylaldehyde, 5-(Dimethylamino)-2-formylphenol 4-(DiMethylaMino)-2-Hydroxybenzaldehyde Hydrochloride 4-N,N-Dimethylaminosalicylaldehyde p-(Dimethylamino)salicylaldehyde Benzaldehyde,4-(diMethylaMino)-2-hydroxy- 4-(N,N-Dimethylamino)-2-hydroxybenzaldehyde 4-Dimethylamino-2-hydroxybenzaldehyde 98% 41602-56-6 41602-51-6