2-Aminobenzyl cyanide
- CAS No.
- 2973-50-4
- Chemical Name:
- 2-Aminobenzyl cyanide
- Synonyms
- o-Aminobenzyl cyanide;2-AMINOBENZYL CYANIDE;2-(Cyanomethyl)aniline;2-AMinobenzyl cyanide 97%;O-AMINOPHENYLACETONITRILE;2-AMINOPHENYLACETONITRILE;2-aminophenylethylnitrile;2-Aminobenzeneacetonitrile;Benzeneacetonitrile, 2-amino-;2-(2-azanylphenyl)ethanenitrile
- CBNumber:
- CB6206936
- Molecular Formula:
- C8H8N2
- Molecular Weight:
- 132.16
- MDL Number:
- MFCD00091082
- MOL File:
- 2973-50-4.mol
- MSDS File:
- SDS
| Melting point | 69-72 °C (lit.) |
|---|---|
| Boiling point | 321°C |
| Density | 1.120±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO, Methanol |
| pka | 3.24±0.10(Predicted) |
| form | Powder |
| color | Off-white |
| Exposure limits | NIOSH: IDLH 25 mg/m3 |
| InChI | 1S/C8H8N2/c9-6-5-7-3-1-2-4-8(7)10/h1-4H,5,10H2 |
| InChIKey | LMDPYYUISNUGGT-UHFFFAOYSA-N |
| SMILES | Nc1ccccc1CC#N |
| CAS DataBase Reference | 2973-50-4(CAS DataBase Reference) |
| FDA UNII | PE7ZN32FVB |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H312-H315-H319-H332-H335-H302+H312+H332 | |||||||||
| Precautionary statements | P304+P340-P305+P351+P338-P405-P501a-P261-P280-P301+P312+P330 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 23/24/25-36/37/38 | |||||||||
| Safety Statements | 26-36/37/39-45 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | 6.1 | |||||||||
| HS Code | 2926907090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Dermal Acute Tox. 4 Inhalation Acute Tox. 4 Oral |
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| NFPA 704 |
|
2-Aminobenzyl cyanide price More Price(54)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 349992 | 2-Aminobenzyl cyanide 97% | 2973-50-4 | 250mg | $40.8 | 2023-01-07 | Buy |
| Sigma-Aldrich | 349992 | 2-Aminobenzyl cyanide 97% | 2973-50-4 | 1g | $58.6 | 2023-01-07 | Buy |
| TCI Chemical | A2997 | 2-Aminobenzyl Cyanide >98.0%(GC)(T) | 2973-50-4 | 200mg | $52 | 2026-04-30 | Buy |
| TCI Chemical | A2997 | 2-Aminobenzyl Cyanide >98.0%(GC)(T) | 2973-50-4 | 1g | $171 | 2026-04-30 | Buy |
| TRC | TRC-A596920-250MG | 2-Aminobenzylcyanide | 2973-50-4 | 250mg | $65 | 2026-06-03 | Buy |
2-Aminobenzyl cyanide Chemical Properties, Uses, Production
Chemical Properties
Brown Solid
Uses
2-Aminobenzyl cyanide may be used in the preparation of oxindole.
Synthesis
610-66-2
2973-50-4
General procedure for the synthesis of o-aminophenylacetonitrile from 2-nitrophenylacetonitrile: 2-nitrophenylacetonitrile (30 g, 185 mmol) and 10% palladium/carbon catalyst (2 g) were suspended in acetic acid (450 mL). The suspension was transferred to a Parr hydrogenation unit and the hydrogenation reaction was carried out at 30 psi hydrogen pressure and room temperature for 2 hours. Upon completion of the reaction, the reaction mixture was filtered through a Celite pad to remove the catalyst. The filtrate was concentrated to dryness under reduced pressure. The resulting residue was dissolved in ethyl acetate (250 mL) and washed sequentially with water (2 x 100 mL) and saturated sodium chloride solution (50 mL). The organic phase was dried over anhydrous sodium sulfate, filtered and concentrated. The crude product was purified by column chromatography (100-200 mesh silica gel) using petroleum ether solution of 8% ethyl acetate as eluent to give o-aminophenylacetonitrile (13.5 g, 55% yield) as a white solid.1H NMR (CDCl3) δ ppm: 7.3-7.1 (m, 2H), 6.9-6.7 (m, 2H), 3.7 (br, 2H), 3.5 (s, 2H).
References
[1] Chemical and Pharmaceutical Bulletin, 1983, vol. 31, # 10, p. 3424 - 3445
[2] Patent: US2011/111046, 2011, A1. Location in patent: Page/Page column 17
[3] Patent: WO2011/58473, 2011, A1. Location in patent: Page/Page column 34; 35
[4] Tetrahedron Letters, 2006, vol. 47, # 2, p. 159 - 162
[5] Journal of the American Chemical Society, 1950, vol. 72, p. 3047,3049
2-Aminobenzyl cyanide Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| China Langchem Inc. | 0086-21-58956006 | China | 7798 | 57 | |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| Wuhan Haizheng Industry & Trade Development Co. Ltd | 027-8866 0053/88660577/88660578 | China | 1070 | 55 | |
| Shanghai civi chemical technology co.,Ltd | 86-21-34053660 | sale@labgogo.com | China | 9853 | 52 |
View Latest Price from 2-Aminobenzyl cyanide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-04 | 2-Aminobenzyl cyanide
2973-50-4
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | ||
 |
2019-12-31 | 2-Aminobenzyl cyanide
2973-50-4
|
$1.00 | 1KG | 99% | 200kg | Career Henan Chemical Co |
-
- 2-Aminobenzyl cyanide
2973-50-4
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 2-Aminobenzyl cyanide
2973-50-4
- $1.00
- 99%
- Career Henan Chemical Co
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