Ethyl 4-fluoro-3-nitrobenzoate
- CAS No.
- 367-80-6
- Chemical Name:
- Ethyl 4-fluoro-3-nitrobenzoate
- Synonyms
- RARECHEM AL BI 0858;4-fluoro-3-nitro-benzoate;Ethyl 3-Nitro-4-Fluorobenzoate;ETHYL 4-FLUORO-3-NITROBENZOATE;Ethyl 4-fluoro-3-nitrobenzoate-2;5-(Ethoxycarbonyl)-2-fluoronitrobenzene;4-FLUORO-3-NITROBENZOIC ACID ETHYL ESTER;Benzoic acid, 4-fluoro-3-nitro-, ethyl ester
- CBNumber:
- CB6229357
- Molecular Formula:
- C9H8FNO4
- Molecular Weight:
- 213.16
- MDL Number:
- MFCD03428515
- MOL File:
- 367-80-6.mol
- MSDS File:
- SDS
| Melting point | 45.3 °C |
|---|---|
| Boiling point | 312.3±22.0 °C(Predicted) |
| Density | 1.333±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| form | crystalline powder |
| color | Pale creamy lemon |
| CAS DataBase Reference | 367-80-6(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2918300090 |
Ethyl 4-fluoro-3-nitrobenzoate price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FF70406 | Ethyl 4-Fluoro-3-nitrobenzoate | 367-80-6 | 50g | $150 | 2026-06-04 | Buy |
| Biosynth | FF70406 | Ethyl 4-Fluoro-3-nitrobenzoate | 367-80-6 | 25g | $150 | 2026-06-04 | Buy |
| Biosynth | FF70406 | Ethyl 4-Fluoro-3-nitrobenzoate | 367-80-6 | 100g | $156 | 2026-06-04 | Buy |
| Biosynth | FF70406 | Ethyl 4-Fluoro-3-nitrobenzoate | 367-80-6 | 250g | $357.5 | 2026-06-04 | Buy |
| Apolloscientific | PC1485 | Ethyl 4-fluoro-3-nitrobenzoate ≥95% | 367-80-6 | 5g | $21 | 2026-06-04 | Buy |
Ethyl 4-fluoro-3-nitrobenzoate Chemical Properties, Uses, Production
Synthesis
64-17-5
453-71-4
367-80-6
Step 1: 5.00 g (27.0 mmol) of 4-fluoro-3-nitrobenzoic acid was dissolved in 50 mL of saturated ethanolic hydrochloric acid solution (1.25 M) and the reaction was refluxed for 15 hours. After completion of the reaction, the reaction mixture was evaporated using a rotary evaporator. Purification by fast column chromatography [silica gel, eluent petroleum ether/ethyl acetate (4:1)] afforded 5.48 g (25.7 mmol, 95%) of ethyl 4-fluoro-3-nitrobenzoate as a colorless solid. Thin layer chromatography (TLC) Rf = 0.48 [silica gel, petroleum ether/ethyl acetate (4:1)]. Mass Spectrometry (ESI) m/z: [M + H]+ calculated value of 214.
References
[1] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 7, p. 1859 - 1863
[2] Patent: US2007/112033, 2007, A1. Location in patent: Page/Page column 17-18
[3] Patent: US2013/79306, 2013, A1. Location in patent: Paragraph 0226; 0227; 0228; 0229
[4] Journal of Medicinal Chemistry, 2012, vol. 55, # 16, p. 7262 - 7272
[5] Journal of Medicinal Chemistry, 2018, vol. 61, # 4, p. 1646 - 1663
Ethyl 4-fluoro-3-nitrobenzoate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| TAIYUAN RHF CO.,LTD. | +86 351 7031519 | sales@RHFChem.com | China | 2334 | 56 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shijiazhuang Sdyano Fine Chemical Co., Ltd. | 0311-89250318 13582355795 | master@sjzsdyn.com | China | 2776 | 65 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shanghai Ennopharm Co., Ltd. | +86 (21) 6435-5022 | China | 4263 | 65 |
View Latest Price from Ethyl 4-fluoro-3-nitrobenzoate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-25 | Ethyl 4-fluoro-3-nitrobenzoate
367-80-6
|
$3.00-9.00 | 99% | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |||
 |
2020-01-03 | Ethyl 4-fluoro-3-nitrobenzoate
367-80-6
|
$1.00 | 1KG | 99% | 10000KGS | Career Henan Chemical Co |
-
- Ethyl 4-fluoro-3-nitrobenzoate
367-80-6
- $3.00-9.00
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- Ethyl 4-fluoro-3-nitrobenzoate
367-80-6
- $1.00
- 99%
- Career Henan Chemical Co
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