trans-Dichlorodiamineplatinum(II)
- CAS No.
- 14913-33-8
- Chemical Name:
- trans-Dichlorodiamineplatinum(II)
- Synonyms
- transplatin;TRANS-DIAMMINEDICHLOROPLATINUM(II);PLATINOL;trans-dichlorodiammineplatinum;CPDC;CIS-DDP;PLATINEX;BRIPLATIN;CISPLATYL;CISMAPLAT
- CBNumber:
- CB6236182
- Molecular Formula:
- Cl2H6N2Pt
- Molecular Weight:
- 300.04
- MDL Number:
- MFCD00011623
- MOL File:
- 14913-33-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 340 °C (dec.)(lit.) |
|---|---|
| storage temp. | 2-8°C |
| solubility | DMSO (Sparingly) |
| form | crystalline |
| pka | 5.63 |
| color | yellow |
| Water Solubility | Soluble in dimethylsulfoxide and dimethylformamide. Slightly soluble in water. |
| Exposure limits |
ACGIH: TWA 0.002 mg/m3 NIOSH: IDLH 4 mg/m3; TWA 0.002 mg/m3 |
| Major Application | pharmaceutical (small molecule) |
| InChI | InChI=1S/2ClH.2H2N.Pt/h2*1H;2*1H2;/q;;2*-1;+4/p-2 |
| InChIKey | DQLATGHUWYMOKM-UHFFFAOYSA-L |
| SMILES | [Pt+2](N)(N)([Cl-])[Cl-] |
| NCI Dictionary of Cancer Terms | Platinol |
| FDA UNII | BW0OY6ZTD4 |
| EPA Substance Registry System | Platinum, diamminedichloro-, (SP-4-1)- (14913-33-8) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H317-H318-H334 | |||||||||
| Precautionary statements | P280-P302+P352-P305+P351+P338+P310 | |||||||||
| Hazard Codes | T,Xn | |||||||||
| Risk Statements | 45-25-41-68-42/43-40-23/24/25 | |||||||||
| Safety Statements | 53-26-39-45-36/37-24-23 | |||||||||
| RIDADR | UN 3288 6.1/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | TP2455000 | |||||||||
| F | 10-21 | |||||||||
| HazardClass | 6.1(a) | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 28439000 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Dam. 1 Resp. Sens. 1 Skin Sens. 1 |
|||||||||
| Hazardous Substances Data | 14913-33-8(Hazardous Substances Data) | |||||||||
| Toxicity | mouse,LD50,intraperitoneal,27mg/kg (27mg/kg),Chemico-Biological Interactions. Vol. 5, Pg. 415, 1972. | |||||||||
| NFPA 704 |
|
trans-Dichlorodiamineplatinum(II) price More Price(47)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0001018 | Cisplatin impurity A European Pharmacopoeia (EP) Reference Standard | 14913-33-8 | 15 mg | $241 | 2026-04-30 | Buy |
| Sigma-Aldrich | PHR3252 | Transplatin pharmaceutical secondary standard, certified reference material | 14913-33-8 | 50MG | $668 | 2026-04-30 | Buy |
| Sigma-Aldrich | P1525 | trans-Platinum(II)diammine dichloride | 14913-33-8 | 1g | $357 | 2026-04-30 | Buy |
| Sigma-Aldrich | BP544 | Transplatin British Pharmacopoeia (BP) Reference Standard | 14913-33-8 | 25MG | $292 | 2026-04-30 | Buy |
| Sigma-Aldrich | 1672803 | Transplatin United States Pharmacopeia (USP) Reference Standard | 14913-33-8 | 25mg | $1390 | 2026-04-30 | Buy |
trans-Dichlorodiamineplatinum(II) Chemical Properties,Uses,Production
Chemical Properties
Yellow Powder or Crystal
Uses
Transplatin is the trans stereoisomer impurity of trans-Dichlorodiamineplatinum(II), an antineoplastic used in the treatment of sarcomas, some carcinomas, lymphomas, and germ cell tumors. Transplatin binds to DNA but does not exhibit the same useful pharmacological effect as its cis stereoisomer.
Uses
Transplatin is the trans stereoisomer impurity of Cisplatin (C499500), an antineoplastic used in the treatment of sarcomas, some carcinomas, lymphomas, and germ cell tumors. Transplatin binds to DNA but does not exhibit the same useful pharmacological effect as its cis stereoisomer.
Definition
ChEBI: A diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a trans planar configuration around the central platinum ion. Unlike its cis-isomer, cisplatin, it does not exhibit any useful pharmacological effect and is toxic.
Safety Profile
Poison by intraperitoneal route. Questionable carcinogen with experimental tumorigenic data. Human mutation data reported. See also PLATINUM COMPOUNDS. When heated to decomposition it emits toxic fumes of NOx and Cl-.
trans-Dichlorodiamineplatinum(II) Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Baoji Funuokang Industrial Co., Ltd | 0917-3236817 13220096790 | 1754423088@qq.com | China | 2995 | 58 |
| Nanjing JiuSiNuo Biopharmaceutical Technology Co., Ltd | 18851976882 | chensheng870628@126.com | China | 59 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
View Lastest Price from trans-Dichlorodiamineplatinum(II) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-11 | trans-Dichlorodiamineplatinum(II)
14913-33-8
|
10G | 98%min | 30kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-08-25 | trans-Dichlorodiamineplatinum(II)
14913-33-8
|
$2.00-5.00 | 1kg | 99% | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
 |
2019-09-02 | trans-Dichlorodiamineplatinum(II)
14913-33-8
|
$7.00 | 1KG | 99% | 1000kg | Career Henan Chemical Co |
-
- trans-Dichlorodiamineplatinum(II)
14913-33-8
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- trans-Dichlorodiamineplatinum(II)
14913-33-8
- $2.00-5.00
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- trans-Dichlorodiamineplatinum(II)
14913-33-8
- $7.00
- 99%
- Career Henan Chemical Co
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