(+)-Piresil-4-O-beta-D-glucopyraside
- CAS No.
- 69251-96-3
- Chemical Name:
- (+)-Piresil-4-O-beta-D-glucopyraside
- Synonyms
- (+)-pinor;Pinoresinol 4-glucoside;Pinoresinol 4-O-glucoside;Pinoresinol 4-glucoside-RM;(+)-pinoresinol-β-D-glucoside;Terpineol-4-o- β- D-glucoside;(+)-pinoresinol-b-D-glucoside;PINORESINOL 4-O-GLUCOSIDE 98%;(+)-pinoresinol-β-D-glucoside;(+)-Piresil-4-O-β-D-glucopyraside
- CBNumber:
- CB62519179
- Molecular Formula:
- C26H32O11
- Molecular Weight:
- 520.53
- MDL Number:
- MFCD17214935
- MOL File:
- 69251-96-3.mol
- MSDS File:
- SDS
Melting point | 102-104 °C(Solv: methanol (67-56-1)) |
---|---|
Boiling point | 752.5±60.0 °C(Predicted) |
Density | 1.418±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C |
pka | 9.84±0.35(Predicted) |
form | Solid |
color | White to light yellow |
InChIKey | QLJNETOQFQXTLI-DUAOPOKGNA-N |
SMILES | O(C1=C(C=CC([C@H]2OC[C@]3([H])[C@@H](C4C=CC(O)=C(OC)C=4)OC[C@]23[H])=C1)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)C |&1:6,9,11,23,27,28,29,31,33,r| |
UNSPSC Code | 41116107 |
NACRES | NA.24 |
(+)-Piresil-4-O-beta-D-glucopyraside price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | PHL84251 | Pinoresinol 4-glucoside phyproof® Reference Substance | 69251-96-3 | 10 mg | $408 | 2025-07-31 | Buy |
Usbiological | 300794 | Pinoresinol 4-O-glucoside | 69251-96-3 | 20mg | $722 | 2021-12-16 | Buy |
ApexBio Technology | N2022 | (+)-Piresil-4-O-beta-D-glucopyraside | 69251-96-3 | 20mg | $500 | 2021-12-16 | Buy |
Arctom | AS111007 | (+)-pinoresinol-β-D-glucoside 97% | 69251-96-3 | 5mg | $101 | 2021-12-16 | Buy |
AvaChem | 2972 | Pinoresinol-beta-D-glucoside | 69251-96-3 | 5mg | $145 | 2021-12-16 | Buy |
(+)-Piresil-4-O-beta-D-glucopyraside Chemical Properties,Uses,Production
Chemical Properties
Soluble in methanol, ethanol, DMSO and other organic solvents, derived from Forsythia.
Uses
(+)-Piresil-4-O-beta-D-glucopyraside is used for content determination/identification/pharmacological experiments, etc.
Definition
ChEBI: (+)-Pinoresinol 4-O-glucoside is a lignan and a glycoside.
Biological Activity
Pinoresinol 4-O-β-D-glucopyranoside ((+)-Pinoresinol 4-O-β-D-glucopyranoside) is the main active furofuranoside lignan in Forsythia. It has antioxidant, hypotensive and cyclic adenosine monophosphate (cAMP) phosphodiesterase inhibitory effects.
in vivo
Pinoresinol 4-O-β-D-glucopyranoside (50 mg/kg; p.o.; 20 days for hepatoprotective activity test, 10 days for antihyperglycaemic activity test) exhibits hepatoprotective activity by lowering AST and ALT levels in CCl4 (HY-Y0298)-induced hepatotoxicity mice, and shows antihyperglycaemic activity by causing a prominent decline in serum glucose level and a promising elevation in insulin level in Streptozotocin (HY-13753)-treated mice[4].
Pinoresinol 4-O-β-D-glucopyranoside (25-50 mg/kg; p.o.; twice with the second dose 1 h before pilocarpine injection) ameliorates the seizures in a dose-dependent manner in lithium/Pilocarpine (HY-B0726A)-induced epileptic seizures rats, manifested by retarding seizure onset, reducing the number of rats developing seizures, and enhancing the survival of animals after seizure exposure[7].
Animal Model: | Male Swiss albino mice (weight: 27-30 g), CCl4-induced hepatotoxicity model and Streptozotocin-induced hyperglycaemia model[4] |
Dosage: | 50 mg/kg b.w. |
Administration: | Oral gavage (p.o.), 20 days in the hepatotoxicity experiment; 10 days in the hyperglycaemia experiment |
Result: | Led to a 33.94% decline in AST, a 3.01% decline in ALT, and a 49.96% decline in LPO levels (in the CCl4-induced hepatotoxicity model). Significantly enhanced CAT, SOD, and TAS levels by 130%, 90.45%, and 61.39% respectively compared to the CCl4-treated group (in the CCl4-induced hepatotoxicity model). Caused a 37.83% reduction in serum glucose level and a 25.37% increase in insulin level (in the Streptozotocin-induced hyperglycaemia model). Reduced lipid peroxide levels by 51.77% and increased serum levels of CAT, SOD, and TAS by 93.02%, 70.79%, and 101.90%, respectively (in the Streptozotocin-induced hyperglycaemia model). |
(+)-Piresil-4-O-beta-D-glucopyraside Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 997 | 58 |
Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 3751 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29800 | 58 |
Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10242 | 58 |
Aktin Chemicals, Inc. | 028-85159085 | info@aktinchem.com | CHINA | 1025 | 58 |
View Lastest Price from (+)-Piresil-4-O-beta-D-glucopyraside manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2024-04-12 | (+)-Piresil-4-O-beta-D-glucopyraside
69251-96-3
|
US $0.00 / kg | 1kg | 99% | 2000ton | Shaanxi Haibo Biotechnology Co., Ltd | |
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2023-02-24 | Pinoresinol 4-O-beta-D-glucopyranoside
69251-96-3
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
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2020-03-10 | (+)-Piresil-4-O-beta-D-glucopyraside
69251-96-3
|
US $6.00 / KG | 1KG | 98% | 1kg, 5kg ,50kg | Career Henan Chemical Co |
-
- (+)-Piresil-4-O-beta-D-glucopyraside
69251-96-3
- US $0.00 / kg
- 99%
- Shaanxi Haibo Biotechnology Co., Ltd
-
- Pinoresinol 4-O-beta-D-glucopyranoside
69251-96-3
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
-
- (+)-Piresil-4-O-beta-D-glucopyraside
69251-96-3
- US $6.00 / KG
- 98%
- Career Henan Chemical Co