ChemicalBook >> CAS DataBase List >>Aconitase Assay Kit

Aconitase Assay Kit

CAS No.
Chemical Name:
Aconitase Assay Kit
Synonyms
Aconitase Assay Kit
CBNumber:
CB62590150
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file
Last updated:2026-05-28 04:13:10

Aconitase Assay Kit Properties

storage temp. -20°C
UNSPSC Code 12161503
NACRES NA.84

SAFETY

Risk and Safety Statements

Symbol(GHS)  Health Hazard (GHS08)
GHS08
Signal word  Danger
Hazard statements  H334
Precautionary statements  P261-P284-P501
Storage Class 10 - Combustible liquids
Hazard Classifications Resp. Sens. 1

Aconitase Assay Kit price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich MAK337 Aconitase Assay Kit sufficient for 100 colorimetric tests 1 kit $453 2026-04-30 Buy
Cayman Chemical 705502 Aconitase Assay Kit 96Well $352 2026-04-30 Buy
Product number Packaging Price Buy
MAK337 1 kit $453 Buy
705502 96Well $352 Buy

Aconitase Assay Kit Chemical Properties, Uses, Production

Description

Aconitase is an iron-sulfur protein containing a [Fe4S4]2+ cluster that catalyzes the stereospecific isomerization of citrate to isocitrate via cis-aconitate. Whereas exposure of aconitase to oxidants renders the enzyme inactive, loss of aconitase activity in cells or in biological samples treated with pro-oxidants has been interpreted as a measure of oxidative damage. Cayman’s Aconitase Assay Kit provides a simple, reproducible, and sensitive tool for assaying aconitase from tissue homogenates or cell lysates. In this assay, citrate is isomerized by aconitase into isocitrate, which is then converted to α-ketoglutarate in a reaction catalyzed by isocitric dehydrogenase. These reactions are monitored by measuring the increase in absorbance at 340 nm associated with the formation of NADPH. The rate of NADPH production is proportional to aconitase activity.

References

[1] CHIRANJEEVI SANDI. Generation and characterisation of Friedreich ataxia YG8R mouse fibroblast and neural stem cell models.[J]. PLoS ONE, 2014: e89488. DOI: 10.1371/journal.pone.0089488
[2] MD Y S C, PHD , PHD  Rong T M, et al. Preservation of myocardial fatty acid oxidation prevents diastolic dysfunction in mice subjected to angiotensin II infusion[J]. Journal of molecular and cellular cardiology, 2016, 100: Pages 64-71. DOI: 10.1016/j.yjmcc.2016.09.001
[3] JAYASRI NANDURI. Xanthine oxidase mediates hypoxia-inducible factor-2α degradation by intermittent hypoxia.[J]. PLoS ONE, 2013: e75838. DOI: 10.1371/journal.pone.0075838

Aconitase Assay Kit Preparation Products And Raw materials

Raw materials

Preparation Products

Aconitase Assay Kit