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4-(alpha-Methylbenzyl)resorcinol

CAS No.
85-27-8
Chemical Name:
4-(alpha-Methylbenzyl)resorcinol
Synonyms
Phenylethyl Resorcinol;Symwhite;Phenethyl resorcinol;4-(1-Phenylethyl)benzene-1,3-diol;LGB-PR;C14H14O2;Phenythyl resorcinol;Symwhite 377;BioActive PRL;NanoActive 377
CBNumber:
CB62604206
Molecular Formula:
C14H14O2
Molecular Weight:
214.26
MDL Number:
MFCD21648466
MOL File:
85-27-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-08-26 13:41:44

4-(alpha-Methylbenzyl)resorcinol Properties

Melting point 78-79℃
Boiling point 244°C/12mmHg(lit.)
Density 1.171
vapor pressure 0Pa at 20℃
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform (Slightly), Ethyl Acetate (Slightly)
form Solid
pka 9.77±0.40(Predicted)
color Light Beige to Pale Brown
Water Solubility 3.85g/L at 20℃
Cosmetics Ingredients Functions ANTIOXIDANT
InChI InChI=1S/C14H14O2/c1-10(11-5-3-2-4-6-11)13-8-7-12(15)9-14(13)16/h2-10,15-16H,1H3
InChIKey PQSXNIMHIHYFEE-UHFFFAOYSA-N
SMILES C1(O)=CC=C(C(C2=CC=CC=C2)C)C(O)=C1
LogP 2.11 at 22℃
EWG's Food Scores 1
FDA UNII G37UFG162O

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
HS Code  2907290090
REACH Registrations Active

4-(alpha-Methylbenzyl)resorcinol price More Price(32)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical M2754 4-(α-Methylbenzyl)resorcinol >98.0%(GC) 85-27-8 1g $55 2026-04-30 Buy
TCI Chemical M2754 4-(α-Methylbenzyl)resorcinol >98.0%(GC) 85-27-8 5g $188 2026-04-30 Buy
ChemScene CS-0099447 4-(1-Phenylethyl)resorcinol ≥98% 85-27-8 1g $9 2026-06-04 Buy
ChemScene CS-0099447 4-(1-Phenylethyl)resorcinol ≥98% 85-27-8 10g $28 2026-06-04 Buy
ChemScene CS-0099447 4-(1-Phenylethyl)resorcinol ≥98% 85-27-8 25g $35 2026-06-04 Buy
Product number Packaging Price Buy
M2754 1g $55 Buy
M2754 5g $188 Buy
CS-0099447 1g $9 Buy
CS-0099447 10g $28 Buy
CS-0099447 25g $35 Buy

4-(alpha-Methylbenzyl)resorcinol Chemical Properties, Uses, Production

Uses

4-(1-Phenylethyl)-1,3-benzenediol is an novel active ingredient of highly efficient skin lightening agents.

Flammability and Explosibility

Non flammable

Synthesis

1,2-Ethanediyl, 1-phenyl- (9CI)

292638-84-7

Resorcinol

108-46-3

4-(alpha-Methylbenzyl)resorcinol

85-27-8

1) Under nitrogen protection, 231 g (2.1 mol) of resorcinol, 4.62 g of the solid acid H2SO4-SiO2, and 220 mL of toluene were added to a reactor, heated to 95 °C, and maintained at that temperature. Subsequently, 104 g (1 mol) of styrene was slowly added dropwise to the reactor at a controlled rate for 1 hour. After completion of the dropwise addition, the reaction was continued at 95 °C for 1 h to obtain the reaction mixture. 2) After completion of the reaction, the reaction mixture was filtered to remove the solid acid H2SO4-SiO2. 150 mL of 0.5% aqueous sodium bicarbonate was added to the filtrate for extraction to separate the organic phase. The organic phase was washed twice more (150 mL each) with deionized water. The organic phase was collected and toluene was removed by rotary evaporator. Subsequently, 250 mL of a mixed solution of hexane and toluene (1:5, v/v) was added for recrystallization, and 177.6 g of white crystal product was obtained in 83% yield.

References

[1] Patent: CN105237359, 2016, A. Location in patent: Paragraph 0038; 0039; 0040; 0041; 0042; 0043; 0044
[2] DRP/DRBP Org.Chem.,
[3] Journal of Organic Chemistry, 1952, vol. 17, p. 243,247
[4] Bulletin of the Chemical Society of Japan, 1995, vol. 68, # 10, p. 2955 - 2960

292638-84-7
108-46-3
85-27-8
Synthesis of 4-(alpha-Methylbenzyl)resorcinol from 1,2-Ethanediyl, 1-phenyl- (9CI) and Resorcinol

4-(alpha-Methylbenzyl)resorcinol Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 398)
Supplier Tel Email Country ProdList Advantage
Beri Pharma Co., Ltd. 0756-8699456 13427714006 sales@zhberi.com China 199 58
Shanxi jiaernuo Biotechnology Co.,LTD. 19992526222 13992350171 540492555@qq.com China 23 58
Changzhou josenchem Pharmaceutical Chemical Material Co.,Ltd. 519-519-85286950 13338194135 info@josenchem.com China 73 58
Powerful Chemical (Shanghai) Co., Ltd. 021-62211590 18917958225; pwfchem@163.com China 75 58
Xi'an Bright Herb Biotech Co., Ltd. 18165366593 18729593924 1273976566@qq.com China 161 58
Jinan Dexinjia Bio&Tech Co., Ltd 0531-82375880 15098789112 3845379039@qq.com China 1457 58
Guangzhou Hichvan Chemical Co., Ltd. 19128722614 hichvan@163.com China 103 58
Shangqiu Huakang Zhongbang Biotechnology Co., Ltd 13011705167 3838015797@qq.com China 76 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81

View Latest Price from 4-(alpha-Methylbenzyl)resorcinol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-(alpha-Methylbenzyl)resorcinol pictures 2026-09-17 4-(alpha-Methylbenzyl)resorcinol
85-27-8
1kg/Bag ≥98% 50 T/Month Hebei Qujie Technology Co., Ltd.
4-(alpha-Methylbenzyl)resorcinol pictures 2026-09-17 4-(alpha-Methylbenzyl)resorcinol
85-27-8
$300.00-500.00 1kg 99% 5000 HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Symwhite 377 pictures 2026-09-17 Symwhite 377
85-27-8
$1.00 300g 99.8% 20 TONS .GZ HONESTCHEM CO.,LTD
NanoLiposomal 377, NanoLiposomal Phenethyl Resorcinol Nanoactive Phenylethyl Resorcinol LGB-PR 4-(alpha-Methylbenzyl)resorcinol 4-(1-Phenylethyl)resorcin 4-(1-Phenylethyl)resorcinol 1,3-Benzenediol, 4-(1-phenylethyl)- 4-(1-phenylethy)-1,3-benzenediol 4-(1-phenylethyl)-1,3-Benzenediol -Methylbenzyl)resorcinol 4-(α-Methylbenzyl)resorcinol BioActive Phenylethyl Resorcinol Fat-Soluble 377 Water-Soluble 377 BioActive PRL NanoAcive Phenylethyl Resorcinol NanoActive 377 4-(alpha-Methylbenzyl)resorcinol> 4-(1-Phenylethyl)benzene-1,3-diol,98%,GC Nanoactive Phenylethyl Resorcinol Symwhite 377 Powder Nanoactive Phenylethyl Resorcinol (377) Cosmetic Grade Phenylethyl Resorcino Powder CAS 85-27-8 Nanoliposomal Phenethyl Phenylethyl Resorcinol/Symwhite 377 NanoLiposomal Phenethyl Resorcinol 4-(1-Phenylethyl)benzene-1,3-diol|||Phenylethyl resorcinol 4-(aipha-methylbenzyl)resorcinol 4-(1-Phenylethyl)-3-hydroxy-phenol 4-(1-Phenylethyl)benzene-1,3-diol C14H14O2 Phenethyl resorcinol Phenythyl resorcinol Phenylethyl Resorcinol Symwhite Symwhite 377 (Phenyl Ethyl Resorcinol) Symwhite 377 85-27-8 82-27-8 OLED materials,pharm chemical,electronic PP 85-27-8