ChemicalBook >> CAS DataBase List >>4-[3-[4-Cyano-3-(trifluoroMethyl)phenyl]-5,5-diMethyl-4-oxo-2-thioxo-1-iMidazolidinyl]-2-fluoro-N-(Methyl-d3)benzaMide

4-[3-[4-Cyano-3-(trifluoroMethyl)phenyl]-5,5-diMethyl-4-oxo-2-thioxo-1-iMidazolidinyl]-2-fluoro-N-(Methyl-d3)benzaMide

CAS No.
1443331-82-5
Chemical Name:
4-[3-[4-Cyano-3-(trifluoroMethyl)phenyl]-5,5-diMethyl-4-oxo-2-thioxo-1-iMidazolidinyl]-2-fluoro-N-(Methyl-d3)benzaMide
Synonyms
MDV 3100-d3;[2H3]-MDV 3100;Deutenzalutamide;[2H3]-Enzalutamide;Deutenzalutamide-d3;Corticosterone Impurity 7;Deutenzalutamide (HC-1119);4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-(methyl-d3)benzamide;4-[3-[4-Cyano-3-(trifluoroMethyl)phenyl]-5,5-diMethyl-4-oxo-2-thioxo-1-iMidazolidinyl]-2-fluoro-N-(Methyl-d3)benzaMide
CBNumber:
CB62622783
Molecular Formula:
C21H13D3F4N4O2S
Molecular Weight:
467.454438134
MDL Number:
MFCD29045174
MOL File:
1443331-82-5.mol
Last updated:2025-07-16 20:18:59
Product description Number Pack Size Price
MDV3100-d3 M199802 1mg $150
MDV3100-d3 M199802 10mg $1190
MDV3100-d3 D52068 1mg $650

4-[3-[4-Cyano-3-(trifluoroMethyl)phenyl]-5,5-diMethyl-4-oxo-2-thioxo-1-iMidazolidinyl]-2-fluoro-N-(Methyl-d3)benzaMide Properties

Melting point 196-199°C
storage temp. Refrigerator
solubility Chloroform (Slightly), Ethyl Acetate (Slightly)
form Solid
color Off-White to Pale Yellow
InChI InChI=1S/C21H16F4N4O2S/c1-20(2)18(31)28(12-5-4-11(10-26)15(8-12)21(23,24)25)19(32)29(20)13-6-7-14(16(22)9-13)17(30)27-3/h4-9H,1-3H3,(H,27,30)/i3D3
InChIKey WXCXUHSOUPDCQV-HPRDVNIFSA-N
SMILES C(NC([2H])([2H])[2H])(=O)C1=CC=C(N2C(=S)N(C3=CC=C(C#N)C(C(F)(F)F)=C3)C(=O)C2(C)C)C=C1F
FDA UNII 3OKI556HC2

4-[3-[4-Cyano-3-(trifluoroMethyl)phenyl]-5,5-diMethyl-4-oxo-2-thioxo-1-iMidazolidinyl]-2-fluoro-N-(Methyl-d3)benzaMide price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC M199802 MDV3100-d3 1443331-82-5 1mg $150 2021-12-16 Buy
TRC M199802 MDV3100-d3 1443331-82-5 10mg $1190 2021-12-16 Buy
Medical Isotopes, Inc. D52068 MDV3100-d3 1443331-82-5 1mg $650 2021-12-16 Buy
Product number Packaging Price Buy
M199802 1mg $150 Buy
M199802 10mg $1190 Buy
D52068 1mg $650 Buy

4-[3-[4-Cyano-3-(trifluoroMethyl)phenyl]-5,5-diMethyl-4-oxo-2-thioxo-1-iMidazolidinyl]-2-fluoro-N-(Methyl-d3)benzaMide Chemical Properties,Uses,Production

Uses

Deutenzalutamide (Enzalutamide-d3) is a developed deuterium labeled Enzalutamide (MDV3100). Enzalutamide is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells[1].

References

[1] Tran C, et al. Development of a second-generation antiandrogen for treatment of advanced prostate cancer. Science. 2009 May 8;324(5928):787-90. DOI:10.1126/science.1168175

4-[3-[4-Cyano-3-(trifluoroMethyl)phenyl]-5,5-diMethyl-4-oxo-2-thioxo-1-iMidazolidinyl]-2-fluoro-N-(Methyl-d3)benzaMide Preparation Products And Raw materials

Raw materials

Preparation Products

4-[3-[4-Cyano-3-(trifluoroMethyl)phenyl]-5,5-diMethyl-4-oxo-2-thioxo-1-iMidazolidinyl]-2-fluoro-N-(Methyl-d3)benzaMide Suppliers

Global( 38)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32434 58
TargetMol Chemicals Inc.
+1-781-999-5354; support@targetmol.com United States 39031 58
Aladdin Scientific
tp@aladdinsci.com United States 52924 58
TLC Pharmaceutical Standards Ltd. 18012923235; 18012923235 chinasales04@tlcstandards.com.cn China 7970 58
J & K SCIENTIFIC LTD. 18210857532; 18210857532 jkinfo@jkchemical.com China 96815 76
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32321 50
Daicel Chiral Technologies (China)CO.,LTD 021-50460086-9 15921403865 han_yajun@dctc.daicel.com China 4395 65
Shanghai TaoSu Biochemical Technology Co., Ltd. 021-33632979 info@tsbiochem.com China 8065 58
Artis Biotech Co. Ltd. 19138486554 18582380095 sales@artisbio.com China 1910 58
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903 3008007409@qq.com China 71826 60

View Lastest Price from 4-[3-[4-Cyano-3-(trifluoroMethyl)phenyl]-5,5-diMethyl-4-oxo-2-thioxo-1-iMidazolidinyl]-2-fluoro-N-(Methyl-d3)benzaMide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Enzalutamide-d3 pictures 2025-07-16 Enzalutamide-d3
1443331-82-5
US $108.00 / mg 10g TargetMol Chemicals Inc.
4-[3-[4-Cyano-3-(trifluoroMethyl)phenyl]-5,5-diMethyl-4-oxo-2-thioxo-1-iMidazolidinyl]-2-fluoro-N-(Methyl-d3)benzaMide MDV 3100-d3 [2H3]-Enzalutamide [2H3]-MDV 3100 4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-(methyl-d3)benzamide Deutenzalutamide (HC-1119) Deutenzalutamide-d3 Corticosterone Impurity 7 Deutenzalutamide 1443331-82-5 Apoptosis, Aromatics, Heterocycles, Inhibitors, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds