2,2-diMethyl-5-ethoxycarbonyl-1,3-dioxane
- CAS No.
- 82962-54-7
- Chemical Name:
- 2,2-diMethyl-5-ethoxycarbonyl-1,3-dioxane
- Synonyms
- ethyl 2,2-diMethyl-1,3-dioxane-5-carboxylate;2,2-diMethyl-5-ethoxycarbonyl-1,3-dioxane;Methyl 2,2-diMethyl-1,3-dioxane-5-carboxylate;2,2-Dimethyl-[1,3]dioxane-5-carboxylic acid ethyl ester;1,3-Dioxane-5-carboxylic acid, 2,2-dimethyl-, ethyl ester
- CBNumber:
- CB62645346
- Molecular Formula:
- C9H16O4
- Molecular Weight:
- 188.22
- MDL Number:
- MFCD11975772
- MOL File:
- 82962-54-7.mol
- MSDS File:
- SDS
| Boiling point | 75℃ (0.4 Torr) |
|---|---|
| Density | 1.039±0.06 g/cm3 (20 ºC 760 Torr) |
| Flash point | 85.0±23.2℃ |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| Appearance | Colorless to light yellow Liquid |
| InChI | InChI=1S/C9H16O4/c1-4-11-8(10)7-5-12-9(2,3)13-6-7/h7H,4-6H2,1-3H3 |
| InChIKey | MYGMWHATZAFUIU-UHFFFAOYSA-N |
| SMILES | O1CC(C(OCC)=O)COC1(C)C |
2,2-diMethyl-5-ethoxycarbonyl-1,3-dioxane price More Price(45)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FE154173 | Ethyl 2,2-dimethyl-1,3-dioxane-5-carboxylate | 82962-54-7 | 5g | $194.7 | 2026-06-04 | Buy |
| Biosynth | FE154173 | Ethyl 2,2-dimethyl-1,3-dioxane-5-carboxylate | 82962-54-7 | 10g | $324.5 | 2026-06-04 | Buy |
| Biosynth | FE154173 | Ethyl 2,2-dimethyl-1,3-dioxane-5-carboxylate | 82962-54-7 | 25g | $714 | 2026-06-04 | Buy |
| Synthonix | E25552 | ethyl 2,2-dimethyl-1,3-dioxane-5-carboxylate 97.0% | 82962-54-7 | 250mg | $17 | 2026-05-06 | Buy |
| Synthonix | E25552 | ethyl 2,2-dimethyl-1,3-dioxane-5-carboxylate 97.0% | 82962-54-7 | 1g | $23 | 2026-05-06 | Buy |
2,2-diMethyl-5-ethoxycarbonyl-1,3-dioxane Chemical Properties, Uses, Production
Synthesis
51335-75-2
82962-54-7
General procedure for the synthesis of 2,2-dimethyl-5-ethoxycarbonyl-1,3-dioxane-5,5-dicarboxylic acid from diethyl 2,2-dimethyl-1,3-dioxane-5,5-dicarboxylate: a mixture of diethyl 2,2-dimethyl-1,3-dioxane-5,5-dicarboxylate (385 g, 1.5 mol), sodium chloride (105 g, 1.8 mol), water (58 g , 3.2 mol) and dimethyl sulfoxide (1500 mL) were refluxed for 20 hours. After completion of the reaction, the solution was cooled to room temperature, saturated sodium chloride solution (750 mL) was added, and the product was extracted with ether (4 x 600 mL). The combined organic extracts were washed with brine (2 x 150 mL) and dried with anhydrous sodium sulfate. After removal of the solvent by evaporation, the residual oil was purified by distillation to afford 2,2-dimethyl-5-ethoxycarbonyl-1,3-dioxane (220 g, 78% yield) as a colorless liquid.1H NMR (700 MHz, CDCl3, 300K): δ= 4.16 (q, J = 7.3 Hz, 2H), 4.01-4.08 (m, 4H), 2.77- 2.81 (m, 1H), 1.43 (s, 3H), 1.40 (s, 3H), 1.26 (t, J = 7.3Hz, 3H).
References
[1] Synlett, 2017, vol. 28, # 5, p. 583 - 588
[2] Chemical and Pharmaceutical Bulletin, 1993, vol. 41, # 2, p. 339 - 345
[3] Journal of the American Chemical Society, 1987, vol. 109, # 26, p. 8071 - 8081
[4] Journal of Organic Chemistry, 1986, vol. 51, # 14, p. 2637 - 2641
[5] Patent: WO2012/103279, 2012, A2. Location in patent: Page/Page column 16-17
2,2-diMethyl-5-ethoxycarbonyl-1,3-dioxane Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9509 | 58 |
| Shanghai Jian Chao Chemical Technology Co., Ltd. | 150-2103-5486 18017383231 | 983544897@qq.com | China | 9335 | 55 |
| Shanghai Raise Chemical Technology Co.,Ltd | +86-021-50935922 | China | 7854 | 55 | |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Hunan HuaTeng Pharmaceutical Co., Ltd., | 400-8592883 15367835770 | sales@huatengsci.com | China | 5869 | 58 |
| Mashilabs (Shanghai) Co.,Ltd. | 19916721580 | mafarm@126.com | China | 4534 | 58 |
| Hangzhou J&H Chemical Co., Ltd. | 0571-87396432 | sales@jhechem.com | China | 14905 | 59 |
| Nanjing Chalf-Pharm Technology Co., Ltd. | 025-57018978 18251899859 | sales@chalf-pharm.com | China | 5855 | 50 |
| DebyeTec.com Inc. | 18086626237 18086626237 | 2693528373@qq.com | China | 2935 | 56 |
| Nanjing Endesa Bio-tech Co., Ltd. | 025-58862853 18915922038 | sales@endesachem.com | China | 590 | 58 |
