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5'-Guanylic acid

5'-Guanylic acid structure

CAS No.: 85-32-5

Chemical Name:: 5'-Guanylic acid

Synonyms: GMP;5’-gmp;guanylate;GUANYLIC ACID;Guanidylic acid;[(2R,3S,4R,5R)-5-(2-Amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate;G-5′-P;GMP·H2;Guo-5'-P;GMP FREE

CBNumber:: CB6271952

Molecular Formula:: C10H14N5O8P

Molecular Weight:: 363.22

MDL Number:: MFCD00057066

MOL File:: 85-32-5.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 05:41:57

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5'-Guanylic acid Properties

Melting point	220 - 223°C
storage temp.	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility	DMSO (Very Slightly, Heated, Sonicated), Water (Slightly, Sonicated)
form	Solid
Boiling point	64 °C(Press: 0.05 Torr)
Density	2.47±0.1 g/cm3(Predicted)
pka	1.86±0.10(Predicted)
color	White to Off-White
Odor	at 100.00%. odorless
Cosmetics Ingredients Functions	HUMECTANT SKIN CONDITIONING SKIN CONDITIONING - EMOLLIENT
InChI	1S/C10H14N5O8P/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(23-9)1-22-24(19,20)21/h2-3,5-6,9,16-17H,1H2,(H2,19,20,21)(H3,11,13,14,18)
InChIKey	RQFCJASXJCIDSX-UHFFFAOYSA-N
SMILES	O=C(NC(N)=N1)C2=C1N(C=N2)C3C(O)C(C(COP(O)(O)=O)O3)O
LogP	-2.000
CAS DataBase Reference	85-32-5(CAS DataBase Reference)
FDA UNII	16597955EP
EPA Substance Registry System	5'-Guanylic acid (85-32-5)
UNSPSC Code	12352204
NACRES	NA.21

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P280-P305+P351+P338
WGK Germany	WGK 3
TSCA	TSCA listed
Storage Class	11 - Combustible Solids
Hazard Classifications	Acute Tox. 4 Oral
Toxicity	LDLo intraperitoneal in mouse: 1500mg/kg

5'-Guanylic acid price More Price(33)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	TMT00136	(5-(2-Amino-6-oxo-1H-purin-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate	85-32-5	1g	$529	2026-04-30	Buy
Usbiological	296166	Guanosine 5'-monophosphate Asreported	85-32-5	5g	$319	2026-06-03	Buy
Usbiological	296166	Guanosine 5'-monophosphate Asreported	85-32-5	10g	$432	2026-06-03	Buy
Usbiological	296166	Guanosine 5'-monophosphate Asreported	85-32-5	25g	$566	2026-06-03	Buy
Usbiological	296166	Guanosine 5'-monophosphate Asreported	85-32-5	50g	$758	2026-06-03	Buy

Product number	Packaging	Price	Buy
TMT00136	1g	$529	Buy
296166	5g	$319	Buy
296166	10g	$432	Buy
296166	25g	$566	Buy
296166	50g	$758	Buy

5'-Guanylic acid Chemical Properties, Uses, Production

Uses

Biochemical research, flavor potentiator (disodium salt).5-Guanylic Acid is a useful reagent for the chemo- and site-specific reductive amination of N2-guanine oligonucleotides.

Definition

The monophosphoric ester of guanine, i.e., the nucleotide containing guanine, d-ribose, and phosphoric acid. The phosphate may be esterified to either the 2, 3, or 5 carbon of ribose, yielding guanosine-2′-phosphate, guanosine-3′-phosphate, and guanosine-

Synthesis

Under low-temperature conditions, guanosine reacts with a phosphorylating agent (e.g., phosphorus oxychloride POCl3) in an organic solvent (e.g., trimethyl phosphate) to generate the intermediate dichlorophosphate. Subsequently, this intermediate is hydrolyzed in the presence of water or ice to convert into a monophosphate, thereby yielding the target product, 5'-Guanylic acid.

Purification Methods

Crystallise it from water and dry it at 110o. [Beilstein 26 III/IV 3910.]

5'-Guanylic acid Preparation Products And Raw materials

Raw materials

D(+)-Glucose Guanosine Ribonucleic acid guanosine 3'-(dihydrogen phosphate) 2'-guanylic acid

D-Ribose Guanine

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Preparation Products

Ribavirin Disodium 5'-Inosinate CALCIUM5'-GUANYLATE 5'-Guanylic acid, dipotassium salt Guanosine 5'-monophosphate disodium salt

Acyclovir [[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate GDP guanosine 5'-phosphoimidazolide

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5'-Guanylic acid Suppliers

Global Suppliers ( 250)

Supplier	Tel	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Hongene Biotech Corporation	021-64757213	info@hongene.com	China	672	61
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15350	60
Dalian Meilun Biotech Co., Ltd.	0411-62910999 13889544652	sales@meilune.com	China	4765	58
ShangHai YuanYe Biotechnology Co., Ltd.	15026964105	shyysw007@163.com	China	4998	60
Hangzhou Sage Chemical Co., Ltd.	+86057186818502 13588463833	info@sagechem.com	China	10265	58
Beijing HuaMeiHuLiBiological Chemical	010-56205725	waley188@sohu.com	China	12323	58
TCI Europe	320-37350700	sales@tcieurope.eu	Europe	23654	75
Shanghai Tauto Biotech Co., Ltd.	021-51320588	tauto@tautobiotech.com	China	3984	66

Supplier	Advantage
J & K SCIENTIFIC LTD.	76
Hongene Biotech Corporation	61
Shanghai Hanhong Scientific Co.,Ltd.	64
Chemsky (shanghai) International Co.,Ltd	60
Dalian Meilun Biotech Co., Ltd.	58
ShangHai YuanYe Biotechnology Co., Ltd.	60
Hangzhou Sage Chemical Co., Ltd.	58
Beijing HuaMeiHuLiBiological Chemical	58
TCI Europe	75
Shanghai Tauto Biotech Co., Ltd.	66

View Latest Price from 5'-Guanylic acid manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-03-20	5'-Guanylic acid 85-32-5	$10.00	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd
2025-05-23	5'-Guanylic acid 85-32-5	$45.00	1kg	99%	20 tons	Hebei Zhuanglai Chemical Trading Co Ltd
2024-04-27	5'-Guanylic acid 85-32-5	$10.00	1kg	99.7%	200000kg	Ouhuang Engineering Materials (Hubei) Co., Ltd

5'-Guanylic acid
85-32-5
$10.00
99%
Hebei Chuanghai Biotechnology Co., Ltd

5'-Guanylic acid
85-32-5
$45.00
99%
Hebei Zhuanglai Chemical Trading Co Ltd

5'-Guanylic acid
85-32-5
$10.00
99.7%
Ouhuang Engineering Materials (Hubei) Co., Ltd

5'-Guanylic acid Spectrum

5'-Guanylic acid(85-32-5)¹HNMR 5'-Guanylic acid(85-32-5)¹³CNMR

85-32-5 (5'-Guanylic acid) Related Search:

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Creatine phosphate 6-Thioguanine Calcium phosphate 8-AZAGUANINE Trisodium phosphate

FERRIC PHOSPHATE Zinc phosphate Guanosine 5'-monophosphate disodium salt 2-Amino-6-chloropurine Riboside Glycine

Aminoethoxyvinyl glycine hydrochloride L-Dihydroorotic acid Nucleoside phosphorylase bacterial

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GUALOSINE 5'-PHOSPHATE (FEED ACID) GUANOSINE-5'-MONOPHOSPHATE (GMP) FREE ACID 98-100% GUANOSINE-5'-MONOPHOSPHORIC ACID, 97.0% [5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxyphosphonic acid GUANILICACID GUANILLICACID Guanylic Aicd Guanosine-5''-monophosphoric acid (and/or unspecified salts) GUANOSINE 5''-MONOPHOSPHATE ACID Guanidylic acid Guanosine 2μ- & 3μ-monophosphate Mixed Isomers sodium salt Guo-5'-P guanosine-phosphate Guanosine 5'-monophosphate free acid Guanosine 5'-phosphate (GMP) G-5′-P Guanosine 5′-monophosphate from Saccharomyces cerevisiae GMP·H2 [(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxy-2-oxolanyl]methyl phosphate Guanosine monophosphate, BR Guanine 5'-Monophosphate 5’-guanylicacid guanidinemonophosphate guanosine5’-phosphate guanosinemonophosphate 5'-GUANOSINE MONOPHOSPHATE guanosine 5-(dihydrogen phosphate) guanosine 5-monophosphate free acid*sigma grade GMP FREE GUANOSINE 5'-MONOPHOSPHORIC ACID GUANOSINE 5'-MONOPHOSPHATE FREE ACID N-HYDRATE Guanosine 3ˊ(2ˊ)-monophosphate Guanosine acid 5'-GMP·H2 5'-Guanylic acid Solution in Acetonitrile/Water, 100μg/mL ((2R,3S,4R,5R)-5-(2-Amino-6-oxo-1H-purin-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate ((2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate 5'-Guanylic acid USP/EP/BP TIANFUCHEM--85-32-5--5'-Guanylic acid Guanylic acid (5'-GMP) 5'-Guanylic acid Guanosine-5'-monophosphate guanosine-5'-triphosphate trisodium salt monohydrate C14057150 Guanosine-5`-monophosphate Apixaban Impurity 156 (5-(2-Amino-6-oxo-1H-purin-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate Guanosine-5＇-Monophosphate [(2R,3S,4R,5R)-5-(2-Amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate 5’-gmp GMP guanylate GUANYLIC ACID 85-32-5 1644619-42-1 C10H14N5O8P C10H14N5OPP Pharmaceutical Intermediates