ChemicalBook >> CAS DataBase List >>EX-527 (R-enantioMer)
EX-527 (R-enantioMer)
- CAS No.
- 848193-69-1
- Chemical Name:
- EX-527 (R-enantioMer)
- Synonyms
- EX-527(R‰;(R)-Selisistat;EX-527 (R-enantioMer);Selisistat R-enantiomer, 10 mM in DMSO;(R)-SELISISTAT; EX-527(R); EX 527(R); EX527(R);;(R)-6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide;1H-Carbazole-1-carboxamide, 6-chloro-2,3,4,9-tetrahydro-, (1R)-;Sirtuin,Selisistat R enantiomer,inhibit,Selisistat Renantiomer,Inhibitor,(R)-Selisistat
- CBNumber:
- CB62735519
- Molecular Formula:
- C13H13ClN2O
- Molecular Weight:
- 248.71
- MDL Number:
- MFCD28291828
- MOL File:
- 848193-69-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-07-14 16:49:18
| Product description | Number | Pack Size | Price |
| EX-527 R | 474097 | 100mg | $1423 |
| EX 527(R) | FE137671 | 10mg | $262.3 |
| EX 527(R) | FE137671 | 50mg | $918 |
| (R)-Selisistat 98.03% | CS-3575 | 5mg | $357 |
| (R)-Selisistat 98.03% | CS-3575 | 10mg | $531 |
| Boiling point | 531.7±38.0 °C(Predicted) |
|---|---|
| Density | 1.388±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| form | Powder |
| pka | 16.12±0.40(Predicted) |
| color | Light yellow to yellow |
| FDA UNII | N4L745VB64 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H317 |
| Precautionary statements | P280-P305+P351+P338 |
EX-527 (R-enantioMer) price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 474097 | EX-527 R | 848193-69-1 | 100mg | $1423 | 2026-06-03 | Buy |
| Biosynth | FE137671 | EX 527(R) | 848193-69-1 | 10mg | $262.3 | 2026-06-04 | Buy |
| Biosynth | FE137671 | EX 527(R) | 848193-69-1 | 50mg | $918 | 2026-06-04 | Buy |
| ChemScene | CS-3575 | (R)-Selisistat 98.03% | 848193-69-1 | 5mg | $357 | 2026-06-04 | Buy |
| ChemScene | CS-3575 | (R)-Selisistat 98.03% | 848193-69-1 | 10mg | $531 | 2026-06-04 | Buy |
EX-527 (R-enantioMer) Chemical Properties,Uses,Production
Uses
(R)-Selisistat ((R)-EX-527) is a R-enantiomer of Selisistat. Selisistat (EX-527) is a potent and selective SIRT1 inhibitor with IC50 of 98 nM.
Definition
ChEBI: (R)-selisistat is a 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide that has R configuration. It is the inactive enantiomer. It is an enantiomer of a (S)-selisistat.
References
[1] Napper AD, et al. Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1. J Med Chem. 2005 Dec 15;48(25):8045-54. DOI:10.1021/jm050522v
EX-527 (R-enantioMer) Preparation Products And Raw materials
Raw materials
Preparation Products
EX-527 (R-enantioMer) Suppliers
Global( 39)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. | 17702719238 | sales@sun-shinechem.com | China | 1197 | 64 |
| Haoyuan Chemexpress Co., Ltd. | 021-58950125 | info@chemexpress.com | China | 7545 | 61 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4853 | 58 |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 18149758185 | sales-cpd@caerulumpharma.com | China | 3492 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 13636370518 | shyysw007@163.com | China | 89667 | 60 |
| Musechem | +1-800-259-7612 | info@musechem.com | United States | 4648 | 60 |
| Wuhan Sun-shine Bio-technology Corporation Limited | +86-027-6552-2453 | sales@sun-shinechem.com | China | 725 | 58 |
| Nanjing Meihao Pharmaceutical Technology Co., Ltd. | meitaochem@126.com | meitaochem@126.com | China | 19087 | 58 |
View Lastest Price from EX-527 (R-enantioMer) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-14 | Selisistat R-enantiomer
848193-69-1
|
$108.00-272.00 | 99.80% | 10g | TargetMol Chemicals Inc. |
-
- Selisistat R-enantiomer
848193-69-1
- $108.00-272.00
- 99.80%
- TargetMol Chemicals Inc.
848193-69-1(EX-527 (R-enantioMer))Related Search:
EX-527 (R-enantioMer)
(R)-6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide
EX-527(R‰
(R)-Selisistat
(R)-SELISISTAT; EX-527(R); EX 527(R); EX527(R);
Sirtuin,Selisistat R enantiomer,inhibit,Selisistat Renantiomer,Inhibitor,(R)-Selisistat
1H-Carbazole-1-carboxamide, 6-chloro-2,3,4,9-tetrahydro-, (1R)-
Selisistat R-enantiomer, 10 mM in DMSO
848193-69-1
