2-(BroMoMethyl)-1-Methyl-3-nitrobenzene
- CAS No.
- 77378-54-2
- Chemical Name:
- 2-(BroMoMethyl)-1-Methyl-3-nitrobenzene
- Synonyms
- 2-methyl-6-nitrobenzyl bromide;2-(BroMoMethyl)-1-Methyl-3-nitrobenzene;Benzene, 2-(bromomethyl)-1-methyl-3-nitro-;2-(Bromomethyl)-1-methyl-3-nitrobenzene - [B48932]
- CBNumber:
- CB62735807
- Molecular Formula:
- C8H8BrNO2
- Molecular Weight:
- 230.06
- MDL Number:
- MFCD12025269
- MOL File:
- 77378-54-2.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P280-P305+P351+P338-P310 |
2-(BroMoMethyl)-1-Methyl-3-nitrobenzene price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | CDA37854 | 2-(bromomethyl)-1-methyl-3-nitrobenzene | 77378-54-2 | 2.5g | $472 | 2026-06-04 | Buy |
| Activate Scientific | AS46567 | 2-(Bromomethyl)-1-methyl-3-nitrobenzene 97% | 77378-54-2 | 1g | $144 | 2026-06-04 | Buy |
| Activate Scientific | AS46567 | 2-(Bromomethyl)-1-methyl-3-nitrobenzene 97% | 77378-54-2 | 5g | $538 | 2026-06-04 | Buy |
| Matrix Scientific | 295917 | 2-(Bromomethyl)-1-methyl-3-nitrobenzene | 77378-54-2 | 250.00mg | $56 | 2026-05-19 | Buy |
| Matrix Scientific | 295917 | 2-(Bromomethyl)-1-methyl-3-nitrobenzene | 77378-54-2 | 1.00g | $106 | 2026-05-19 | Buy |
2-(BroMoMethyl)-1-Methyl-3-nitrobenzene Chemical Properties, Uses, Production
Synthesis
54915-41-2
77378-54-2
The general procedure for the synthesis of 2-(bromomethyl)-1-methyl-3-nitrobenzene from (2-methyl-6-nitrophenyl)methanol was as follows: benzyl alcohol (2.52 g, 15.07 mmol) was dissolved in CH2Cl2 (0.12 M) under argon protection, and cooled to -78°C. A 1.0 M CH2Cl2 solution of BBr3 was added slowly and dropwise (23 mL 22.6 mmol). The reaction mixture was stirred overnight at room temperature and then diluted with H2O (150 mL). The organic layer was separated, washed with brine, dried over MgSO4 and concentrated to give 2.97 g (86% yield) of 2-methyl-6-nitrobenzyl bromide as a brown solid.1H NMR (400 MHz, CDCl3) δ 2.53 (s, 3H), 4.72 (s, 2H), 7.36 (t, J = 7.8 Hz, 1H), 7.46 (d, J = 7.6 Hz, 1H), 7.75 (d, J = 8.1 Hz, 1H).
References
[1] Journal of Chemical Research, Miniprint, 2001, # 10, p. 1023 - 1055
[2] Patent: WO2006/128142, 2006, A2. Location in patent: Page/Page column 30
[3] Journal of Organic Chemistry, 2011, vol. 76, # 9, p. 3484 - 3497
[4] Bioorganic and Medicinal Chemistry, 2007, vol. 15, # 20, p. 6574 - 6595
[5] Patent: WO2013/162072, 2013, A1. Location in patent: Page/Page column 950; 951
2-(BroMoMethyl)-1-Methyl-3-nitrobenzene Preparation Products And Raw materials
Raw materials
Preparation Products
2-(BroMoMethyl)-1-Methyl-3-nitrobenzene Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ZHIWE CHEMTECH CO LTD | 021-20221225 13917446399 | zwchem@163.com | China | 522 | 61 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Beijing Eternalchem Co,. Ltd. | 010-59484199 18611897322;18611897322; | sales@eternalchem.com | China | 1993 | 60 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Cool Pharm, Ltd | 021-60455363 18019463053 | sales@coolpharm.com | China | 8455 | 58 |
| Zhengzhou Guancheng Laboratory equipment Sales | 0371-88888888 qq272369594;2159423853qq | 2723695949@qq.com | China | 4990 | 50 |
| SuZhou ShiYa Biopharmaceuticals, Inc. | 0512-0512-52358471 17715136450 | sales@shiyabiopharm.com | China | 9814 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Aikon International Limited | 025-66113011 19370895928 | qzhang@aikonchem.com | China | 15390 | 58 |
| Shanghai Jizhi Biochemical Technology Co. Ltd. | 021-4009004166/18616739031 18616739031 | 3007523370@qq.com | China | 40000 | 58 |
