AJMALICINE HYDROCHLORIDE
- CAS No.
- 4373-34-6
- Chemical Name:
- AJMALICINE HYDROCHLORIDE
- Synonyms
- D-YOHIMBINE;AJMALICIN HCL;AJMALICINE HCL;Einecs 224-471-9;RAUBASINE HYDROCHLORIDE;AJMALICINE HYDROCHLORIDE;gamma-yohimbinhydrochloride;gamma-yohimbinehydrochloride;ajmalicine,monohydrochloride;DELTA-YOHIMBINE HYDROCHLORIDE
- CBNumber:
- CB6309103
- Molecular Formula:
- C21H25ClN2O3
- Molecular Weight:
- 388.89
- MDL Number:
- MFCD00278831
- MOL File:
- 4373-34-6.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| AJMALICINE HYDROCHLORIDE 95.00% | HBL0000084 | 10MG | $713.1 |
| More product size | |||
| Melting point | 275-300 °C |
|---|---|
| FDA UNII | I0V9KZN41X |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H319-H315-H335 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| RTECS | AX7890000 |
| F | 10-23 |
AJMALICINE HYDROCHLORIDE price More Price(1)
AJMALICINE HYDROCHLORIDE Chemical Properties,Uses,Production
Uses
Ajmalicine (Raubasine) hydrochloride is a potent adrenolytic agent which preferentially blocks α1-adrenoceptor. Ajmalicine hydrochloride is an reversible but non-competitive nicotine receptor full inhibitor, with an IC50 of 72.3 μM. Ajmalicine hydrochloride also can be used as anti-hypertensive, and serpentine, with sedative activity[1][2].
in vivo
Ajmalicine hydrochloride blocking the pressor action of electrical stimulation and is active against sympathetic stimulation[1].
Ajmalicine hydrochloride (0.5-4 mg/kg) induces a marked dose-dependent inhibition against the pressor response to noradrenaline[1].
| Animal Model: | Male Wistar rats (300-350 g)[1] |
| Dosage: | 0.5, 1, 2, and 4 mg/kg |
| Administration: | IV, once |
| Result: | Induced a marked dose-dependent inhibition against the pressor response to noradrenaline. |
IC 50
α1-adrenergic receptor; α2-adrenergic receptor
Purification Methods
This hydrochloride crystallises from MeOH or EtOH. Its solubility is 0.315g/100g of H2O at 100o. [Beilstein 27 III/IV 7928.]
References
[1] Roquebert J, et al. Inhibition of the alpha 1 and alpha 2-adrenoceptor-mediated pressor response in pithed rats by raubasine, tetrahydroalstonine and akuammigine. Eur J Pharmacol. 1984 Oct 30;106(1):203-5. DOI:10.1016/0014-2999(84)90698-8
[2] Pereira DM, et al. Pharmacological effects of Catharanthus roseus root alkaloids in acetylcholinesterase inhibition and cholinergic neurotransmission. Phytomedicine. 2010 Jul;17(8-9):646-52. DOI:10.1016/j.phymed.2009.10.008
[3] Demichel P, et al. Effects of raubasine stereoisomers on pre- and postsynaptic alpha-adrenoceptors in the rat vas deferens. Br J Pharmacol. 1984 Oct;83(2):505-10 DOI:10.1111/j.1476-5381.1984.tb16514.x
AJMALICINE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| Dideu Industries Group Limited | +86-86-15536356810 +8617392712697 | 1022@dideu.com | China | 29107 | 58 |
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 19956 | 58 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40228 | 62 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 13636370518 | shyysw007@163.com | China | 89686 | 60 |
| Shanghai Jizhi Biochemical Technology Co. Ltd. | 021-4009004166/18616739031 18616739031 | 3007523370@qq.com | China | 52678 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 +86-13028896684; | sales@rrkchem.com | China | 57422 | 58 |
| cjbscvictory | 13348960310 13348960310 | 3003867561@qq.com | China | 10312 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24958 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 | rose.shi@synzest.com | China | 6210 | 58 |
View Lastest Price from AJMALICINE HYDROCHLORIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-22 | Ajmalicine hydrochloride
4373-34-6
|
$2120.00-3700.00 | 10g | TargetMol Chemicals Inc. | |||
 |
2025-11-18 | AJMALICINE HYDROCHLORIDE USP/EP/BP
4373-34-6
|
$1.10 | 1g | 99.9% | 100 Tons min | Dideu Industries Group Limited |
-
- Ajmalicine hydrochloride
4373-34-6
- $2120.00-3700.00
- TargetMol Chemicals Inc.
-
- AJMALICINE HYDROCHLORIDE USP/EP/BP
4373-34-6
- $1.10
- 99.9%
- Dideu Industries Group Limited
