Mal-PEG8-t-butyl ester
- CAS No.
- 2055048-43-4
- Chemical Name:
- Mal-PEG8-t-butyl ester
- Synonyms
- Mal-PEG8-Boc;Mal-PEG8-COOtBu;Mal-PEG8-CH2CH2COOtBu;Mal-PEG8-t-butyl ester;tert-butyl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate;4,7,10,13,16,19,22,25-Octaoxaheptacosanoic acid, 27-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 1,1-dimethylethyl ester;Mal-PEG8-CH2CH2COOtBu/4,7,10,13,16,19,22,25-Octaoxaheptacosanoic acid, 27-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 1,1-dimethylethyl ester
- CBNumber:
- CB63162992
- Molecular Formula:
- C27H47NO12
- Molecular Weight:
- 577.66
- MDL Number:
- MFCD30458029
- MOL File:
- 2055048-43-4.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501 |
Mal-PEG8-t-butyl ester price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0113363 | Mal-PEG8-Boc ≥95% | 2055048-43-4 | 100mg | $43 | 2026-06-04 | Buy |
| ChemScene | CS-0113363 | Mal-PEG8-Boc ≥95% | 2055048-43-4 | 250mg | $85 | 2026-06-04 | Buy |
| ChemScene | CS-0113363 | Mal-PEG8-Boc ≥95% | 2055048-43-4 | 500mg | $161 | 2026-06-04 | Buy |
| ChemScene | CS-0113363 | Mal-PEG8-Boc ≥95% | 2055048-43-4 | 1g | $256 | 2026-06-04 | Buy |
| BroadPharm | bp-23335 | Mal-PEG8-t-butyl ester 98% | 2055048-43-4 | 100MG | $260 | 2026-05-24 | Buy |
Mal-PEG8-t-butyl ester Chemical Properties, Uses, Production
Description
Mal-PEG8-t-butyl ester is a PEG linker containing a maleimide group and a t-butyl ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
Uses
Mal-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Mal-PEG8-t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Amatek Scientific Co. Ltd. | 0512-56316828 400-867-5858;400-867-5858 | info@amateksci.com | China | 28760 | 58 |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4229 | 58 |
| Alpha Biopharmaceuticals Co., Ltd | 0411-39042497 | sales@alphabiopharm.com | China | 1951 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19904 | 58 |
| Shaanxi Xinyan Bomei Biotechnology Co., Ltd. | 13892832556 | 2440688701@qq.com | China | 1981 | 58 |
| Xiamen Sinopeg Biotech Co., Ltd. | 400-9189898 17359873007 | sales@sinopeg.com | China | 1003 | 58 |
| Taizhou Nanfeng Pharmaceutical Research Institute | nanfengpharma@126.co 18616377689 | nanfengpharma@126.com | China | 20008 | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 54996 | 58 |
| Block Chemical Technology (Shanghai) Co., Ltd. | 021-20432219 13918097649 | li_jinfei@acblock-lab.com | China | 10000 | 58 |
View Latest Price from Mal-PEG8-t-butyl ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-06-07 | Mal-PEG8-COOtBu
2055048-43-4
|
1g | >98.00% | 1g | Xian confluore Biological Technology Co., Ltd. |
-
- Mal-PEG8-COOtBu
2055048-43-4
- $0.00
- >98.00%
- Xian confluore Biological Technology Co., Ltd.
