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Azadibenzocyclooctyne-Biotin conjugate

CAS No.
1418217-95-4
Chemical Name:
Azadibenzocyclooctyne-Biotin conjugate
Synonyms
DBCO-Biotin;DBCO-(CH2)2-NH2-BIOTIN;Azadibenzocyclooctyne-Biotin conjugate;DBCO-Biotin,Azadibenzocyclooctyne-Biotin conjugate;(3AS,4S,6aR)-N-[3-(11,12-Didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide;1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]hexahydro-2-oxo-, (3aS,4S,6aR)-
CBNumber:
CB63309380
Molecular Formula:
C28H30N4O3S
Molecular Weight:
502.63
MDL Number:
MFCD22380751
MOL File:
1418217-95-4.mol
MSDS File:
SDS
Last updated:2026-07-16 07:06:08
Product description Number Pack Size Price
DBCO-Biotin 290406-5G 5g $4500
DBCO-Biotin 290406-500MG 500mg $1200
DBCO-Biotin 290406-1G 1g $1800
DBCO-Biotin 290406-100MG 100mg $400
DBCO-Biotin ≥96% CS-0087463 50mg $352

Azadibenzocyclooctyne-Biotin conjugate Properties

Boiling point 905.9±65.0 °C(Predicted)
Density 1.35±0.1 g/cm3(Predicted)
storage temp. -20°C, protect from light, stored under nitrogen
form Solid
pka 13.90±0.40(Predicted)
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

Azadibenzocyclooctyne-Biotin conjugate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemPep 290406-5G DBCO-Biotin 1418217-95-4 5g $4500 2026-06-04 Buy
ChemPep 290406-500MG DBCO-Biotin 1418217-95-4 500mg $1200 2026-06-04 Buy
ChemPep 290406-1G DBCO-Biotin 1418217-95-4 1g $1800 2026-06-04 Buy
ChemPep 290406-100MG DBCO-Biotin 1418217-95-4 100mg $400 2026-06-04 Buy
ChemScene CS-0087463 DBCO-Biotin ≥96% 1418217-95-4 50mg $352 2026-06-04 Buy
Product number Packaging Price Buy
290406-5G 5g $4500 Buy
290406-500MG 500mg $1200 Buy
290406-1G 1g $1800 Buy
290406-100MG 100mg $400 Buy
CS-0087463 50mg $352 Buy

Azadibenzocyclooctyne-Biotin conjugate Chemical Properties,Uses,Production

Uses

DBCO-Biotin is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

IC 50

Alkyl-Chain

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Azadibenzocyclooctyne-Biotin conjugate Preparation Products And Raw materials

Raw materials

Preparation Products

Azadibenzocyclooctyne-Biotin conjugate Suppliers

Global( 37)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32998 60
TargetMol Chemicals Inc.
+1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6290 58
TargetMol Chemicals Inc.
+1-781-999-5354; support@targetmol.com United States 38999 58
Xian confluore Biological Technology Co., Ltd.
+86-15680926068 1924344760@confluore.cn China 2996 58
Shanghai Macklin Biochemical Co.,Ltd. 15221275939 15221275939 shenlinxing@macklin.cn China 15775 55
Shanghai Send Pharmaceutical Technology Co., Ltd. 58088081 18317173152 sale1@shsendpharm.com China 845 55
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4142 58
Binhai gill polypeptide co. LTD 021-61263389 13524856427 Joetang@glschina.com China 9927 58
Shaanxi Xinyan Bomei Biotechnology Co., Ltd. 13892832556 2440688701@qq.com China 1998 58

View Lastest Price from Azadibenzocyclooctyne-Biotin conjugate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
DBCO-Biotin pictures 2026-07-16 DBCO-Biotin
1418217-95-4
$45.00-163.00 99.52% 10g TargetMol Chemicals Inc.
DBCO-Biotin pictures 2025-06-07 DBCO-Biotin
1418217-95-4
25mg >99.00% 100 Xian confluore Biological Technology Co., Ltd.
  • DBCO-Biotin pictures
  • DBCO-Biotin
    1418217-95-4
  • $45.00-163.00
  • 99.52%
  • TargetMol Chemicals Inc.
  • DBCO-Biotin pictures
  • DBCO-Biotin
    1418217-95-4
  • $0.00
  • >99.00%
  • Xian confluore Biological Technology Co., Ltd.
DBCO-Biotin,Azadibenzocyclooctyne-Biotin conjugate Azadibenzocyclooctyne-Biotin conjugate DBCO-(CH2)2-NH2-BIOTIN 1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]hexahydro-2-oxo-, (3aS,4S,6aR)- (3AS,4S,6aR)-N-[3-(11,12-Didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide DBCO-Biotin 1418217-95-4