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Azadibenzocyclooctyne-Biotin conjugate

Azadibenzocyclooctyne-Biotin conjugate structure

CAS No.: 1418217-95-4

Chemical Name:: Azadibenzocyclooctyne-Biotin conjugate

Synonyms: DBCO-Biotin;DBCO-(CH2)2-NH2-BIOTIN;Azadibenzocyclooctyne-Biotin conjugate;DBCO-Biotin,Azadibenzocyclooctyne-Biotin conjugate;(3AS,4S,6aR)-N-[3-(11,12-Didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide;1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]hexahydro-2-oxo-, (3aS,4S,6aR)-

CBNumber:: CB63309380

Molecular Formula:: C28H30N4O3S

Molecular Weight:: 502.63

MDL Number:: MFCD22380751

MOL File:: 1418217-95-4.mol

MSDS File:: SDS

Last updated:2026-04-21 11:20:27

Product description	Number	Pack Size	Price
Biotin-DBCO	LS-4270	100mg	$810
Biotin-DBCO	LS-4270	250mg	$1620
DBCO-Biotin >98%	DC21887	250mg	$1700
DBCO-Biotin >98%	DC21887	1g	$3400
DBCO-Biotin min.95%	288702	100mg	$650

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Azadibenzocyclooctyne-Biotin conjugate Properties

Boiling point	905.9±65.0 °C(Predicted)
Density	1.35±0.1 g/cm3(Predicted)
storage temp.	-20°C, protect from light, stored under nitrogen
form	Solid
pka	13.90±0.40(Predicted)
color	White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P280-P301+P312-P302+P352-P305+P351+P338

Azadibenzocyclooctyne-Biotin conjugate price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Iris Biotech GmbH	LS-4270	Biotin-DBCO	1418217-95-4	100mg	$810	2021-12-16	Buy
Iris Biotech GmbH	LS-4270	Biotin-DBCO	1418217-95-4	250mg	$1620	2021-12-16	Buy
DC Chemicals	DC21887	DBCO-Biotin >98%	1418217-95-4	250mg	$1700	2021-12-16	Buy
DC Chemicals	DC21887	DBCO-Biotin >98%	1418217-95-4	1g	$3400	2021-12-16	Buy
purepeg	288702	DBCO-Biotin min.95%	1418217-95-4	100mg	$650	2021-12-16	Buy

Product number	Packaging	Price	Buy
LS-4270	100mg	$810	Buy
LS-4270	250mg	$1620	Buy
DC21887	250mg	$1700	Buy
DC21887	1g	$3400	Buy
288702	100mg	$650	Buy

Azadibenzocyclooctyne-Biotin conjugate Chemical Properties,Uses,Production

Uses

DBCO-Biotin is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

IC 50

Alkyl-Chain

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Azadibenzocyclooctyne-Biotin conjugate Preparation Products And Raw materials

Raw materials

Preparation Products

Azadibenzocyclooctyne-Biotin conjugate Suppliers

Global( 40)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32467	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6312	58
Alfa Chemistry	+1-5166625404;	Info@alfa-chemistry.com	United States	20405	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	39040	58
Xian confluore Biological Technology Co., Ltd.	+86-15680926068	1924344760@confluore.cn	China	2997	58
Shanghai Macklin Biochemical Co.,Ltd.	15221275939	shenlinxing@macklin.cn	China	15781	55
Shanghai Send Pharmaceutical Technology Co., Ltd.	50266790 18317173152	Hailey@shsendpharm.com	China	904	55
Xi'an Confluore Biological Technology Co., Ltd.	+86-156-80926068 +86-15680926068	1924344760@qq.com	China	4952	58
Binhai gill polypeptide co. LTD	021-61263389 13524856427	Joetang@glschina.com	China	9932	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
TargetMol Chemicals Inc.	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
Alfa Chemistry	58
TargetMol Chemicals Inc.	58
Xian confluore Biological Technology Co., Ltd.	58
Shanghai Macklin Biochemical Co.,Ltd.	55
Shanghai Send Pharmaceutical Technology Co., Ltd.	55
Xi'an Confluore Biological Technology Co., Ltd.	58
Binhai gill polypeptide co. LTD	58

View Lastest Price from Azadibenzocyclooctyne-Biotin conjugate manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-04-21	DBCO-Biotin 1418217-95-4	US $45.00-163.00 / mg		99.52%	10g	TargetMol Chemicals Inc.
	2025-06-07	DBCO-Biotin 1418217-95-4	US $0.00 / mg	25mg	>99.00%	100	Xian confluore Biological Technology Co., Ltd.

DBCO-Biotin
1418217-95-4
US $45.00-163.00 / mg
99.52%
TargetMol Chemicals Inc.

DBCO-Biotin
1418217-95-4
US $0.00 / mg
>99.00%
Xian confluore Biological Technology Co., Ltd.

1418217-95-4(Azadibenzocyclooctyne-Biotin conjugate)Related Search:

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DBCO-Biotin DBCO-Biotin,Azadibenzocyclooctyne-Biotin conjugate Azadibenzocyclooctyne-Biotin conjugate DBCO-(CH2)2-NH2-BIOTIN 1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]hexahydro-2-oxo-, (3aS,4S,6aR)- (3AS,4S,6aR)-N-[3-(11,12-Didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide 1418217-95-4