N-Boc-Azido-tris(ethylenoxy)-L-alanin
- CAS No.
- 2054345-68-3
- Chemical Name:
- N-Boc-Azido-tris(ethylenoxy)-L-alanin
- Synonyms
- Azido-PEG3-Ala-Boc;Boc-D-3-(N3-PEG3)-Ala-OH;O-(N3-PEG2-CH2CH2)-Boc-D-serine;N-Boc-Azido-tris(ethylenoxy)-L-alanin;5,8,11-Trioxa-2-azatridecanoic acid, 13-azido-3-carboxy-, 1-(1,1-dimethylethyl) ester, (3R)-
- CBNumber:
- CB63373723
- Molecular Formula:
- C14H26N4O7
- Molecular Weight:
- 362.38
- MDL Number:
- MFCD31692202
- MOL File:
- 2054345-68-3.mol
N-Boc-Azido-tris(ethylenoxy)-L-alanin price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| aablocks | AA019E6X | 5,8,11-Trioxa-2-azatridecanoic acid, 13-azido-3-carboxy-, 1-(1,1-dimethylethyl) ester, (3R)- ≥95% | 2054345-68-3 | 100mg | $445 | 2026-05-29 | Buy |
| aablocks | AA019E6X | 5,8,11-Trioxa-2-azatridecanoic acid, 13-azido-3-carboxy-, 1-(1,1-dimethylethyl) ester, (3R)- ≥95% | 2054345-68-3 | 250mg | $720 | 2026-05-29 | Buy |
| aablocks | AA019E6X | 5,8,11-Trioxa-2-azatridecanoic acid, 13-azido-3-carboxy-, 1-(1,1-dimethylethyl) ester, (3R)- ≥95% | 2054345-68-3 | 500mg | $1033 | 2026-05-29 | Buy |
| Acrotein | b-2124 | O-(N3-PEG2-CH2CH2)-Boc-D-serine 97% | 2054345-68-3 | 0.1g | $221.8 | 2026-05-25 | Buy |
| Acrotein | b-2124 | O-(N3-PEG2-CH2CH2)-Boc-D-serine 97% | 2054345-68-3 | 0.25g | $443.5 | 2026-05-25 | Buy |
N-Boc-Azido-tris(ethylenoxy)-L-alanin Chemical Properties, Uses, Production
Description
N-Boc-Azido-tris(ethylenoxy)-L-alanin has a Boc protected L-alanine residue and an azido group. The Boc protecting group can be removed under acidic conditions. The azide can react with alkynes, DBCO and BCN under copper-catalyzed Click Chemistry reactions.
Uses
Azido-PEG3-Ala-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG3-Ala-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
N-Boc-Azido-tris(ethylenoxy)-L-alanin Preparation Products And Raw materials
Raw materials
Preparation Products
N-Boc-Azido-tris(ethylenoxy)-L-alanin Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Zhengzhou Akem Chemical Co., Ltd | 13303867194 | 770406999@qq.com | China | 9949 | 58 |
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-80514535 19917294565 | et@chemextension.com | China | 5061 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | ET-market@chemextension.com | China | 38923 | 58 |
| Shandong Dayou Pharmaceutical Research and Development Co., Ltd. | hanfangpharma@126.com 15165037910 | hanfangpharma@126.com | China | 25800 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Amatek Scientific Co. Ltd. | 0512-56316828 4008675858 | sales1@amateksci.com | China | 8528 | 58 |
| Shanghai Yanfen Biochemical Technology Co.,LTD | 13611955358 15002190549 | yanfen2023@126.com | China | 2573 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 50068 | 58 | |
| Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | info@chemextension.com | China | 42052 | 58 |
