ChemicalBook >> CAS DataBase List >>7-Benzyl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyrimidin-4-one hydrochloride

7-Benzyl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyrimidin-4-one hydrochloride

7-Benzyl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyrimidin-4-one hydrochloride structure

CAS No.: 62458-96-2

Chemical Name:: 7-Benzyl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyrimidin-4-one hydrochloride

Synonyms: 7-benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyriMidin-4-ol;7-benzyl-5;4-d]pyriMidin-4(4aH)-one;7-benzyl-3H,4H,5H,6H,7H,8H-pyrido[3,4-d]pyriMidin-4-one;7-Benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4(3H);7-benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4(3H)-one;5,6,7,8-Tetrahydro-7-(phenylmethyl)pyrido[3,4-d]pyrimidin-4(;7-benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4(4aH)-one;7-Benzyl-5,6,7,8-tetrahydro-4aH-pyrido[3,4-d]pyrimidin-4-one;7-BENZYL-5,6,7,8-TETRAHYDROPYRIDO[3,4-D]PYRIMIDIN-4(3H)-ONE HCL

CBNumber:: CB6355377

Molecular Formula:: C14H15N3O

Molecular Weight:: 241.29

MDL Number:: MFCD09030048

MOL File:: 62458-96-2.mol

MSDS File:: SDS

Last updated:2026-09-12 18:54:13

Request For Quotation

7-Benzyl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyrimidin-4-one hydrochloride Properties

Melting point	198 °C
Boiling point	406.5±55.0 °C(Predicted)
Density	1.27
storage temp.	Sealed in dry,Room Temperature
pka	7.77±0.20(Predicted)
Appearance	Light brown to brown Solid
InChI	InChI=1S/C14H15N3O/c18-14-12-6-7-17(9-13(12)15-10-16-14)8-11-4-2-1-3-5-11/h1-5,10H,6-9H2,(H,15,16,18)
InChIKey	NBOPLUXBZUJFHI-UHFFFAOYSA-N
SMILES	C1NC(=O)C2CCN(CC3=CC=CC=C3)CC=2N=1

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H332-H335
Precautionary statements	P261-P280-P305+P351+P338

7-Benzyl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyrimidin-4-one hydrochloride price More Price(40)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Matrix Scientific	069988	7-Benzyl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyrimidin-4-one	62458-96-2	1.00g	$215	2026-05-18	Buy
Matrix Scientific	069988	7-Benzyl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyrimidin-4-one	62458-96-2	5.00g	$665	2026-05-18	Buy
Synthonix	B4275	7-Benzyl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyrimidin-4-one 95%+	62458-96-2	500mg	$30	2026-05-06	Buy
Synthonix	B4275	7-Benzyl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyrimidin-4-one 95%+	62458-96-2	1g	$45	2026-05-06	Buy
Synthonix	B4275	7-Benzyl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyrimidin-4-one 95%+	62458-96-2	5g	$180	2026-05-06	Buy

Product number	Packaging	Price	Buy
069988	1.00g	$215	Buy
069988	5.00g	$665	Buy
B4275	500mg	$30	Buy
B4275	1g	$45	Buy
B4275	5g	$180	Buy

7-Benzyl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyrimidin-4-one hydrochloride Chemical Properties, Uses, Production

Synthesis

3473-63-0

Ethyl N-benzyl-3-oxo-4-piperidine-carboxylate hydrochloride

52763-21-0

7-BENZYL-5,6,7,8-TETRAHYDRO-3H-PYRIDO[3,4-D]PYRIMIDIN-4-ONE HYDROCHLORIDE

62458-96-2

To a mixed solution of sodium methanolate (25 wt% methanol solution, 67.6 mL, 296 mmol) and methanol (70 mL) was sequentially added formamidine acetate (11.00 g, 106 mmol) and ethyl 1-benzyl-3-oxopiperidine-4-carboxylate hydrochloride (25.16 g, 84 mmol) at 25 °C. The reaction mixture was stirred continuously at 25°C for 20 hours. Upon completion of the reaction, the mixture was cooled to 0 °C, water (90 mL) was added followed by slow dropwise addition of acetic acid (6.05 mL, 106 mmol) and stirring was continued at 25 °C for 3 hours. Most of the methanol was removed by distillation under reduced pressure and the reaction mixture was concentrated. The resulting suspension was filtered and the solid product was collected, washed with water and dried under vacuum to afford 7-benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4(3H)-one (16.10 g, 79% yield) as a white solid.LC/MS analysis showed: m/z 242.06 ([M+H]+), retention time 0.598 min (Method 12). .1H-NMR (500 MHz, CDCl3) δ 12.61 (broad single peak, 1H), 7.99 (single peak, 1H), 7.38-7.26 (multiple peaks, 5H), 3.73 (multiple peaks, 2H), 3.50 (multiple peaks, 2H), 2.74 (multiple peaks, 2H), 2.66 (multiple peaks, 2H).

References

[1] Bioorganic and Medicinal Chemistry Letters, 2016, vol. 26, # 1, p. 160 - 167
[2] Patent: WO2009/158396, 2009, A1. Location in patent: Page/Page column 67
[3] Bioorganic and Medicinal Chemistry Letters, 2007, vol. 17, # 18, p. 5019 - 5024
[4] Patent: US2008/275052, 2008, A1. Location in patent: Page/Page column 45

7-Benzyl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyrimidin-4-one hydrochloride Preparation Products And Raw materials

Raw materials

Formamidine acetate Ethyl 1-benzyl-3-oxopiperidine-4-carboxylate Ethyl N-benzyl-3-oxo-4-piperidine-carboxylate hydrochloride Ethyl 1-benzyl-4-oxo-3-piperidinecarboxylate hydrochloride Methanol

Sodium Methoxide

1of2

Preparation Products

7-Benzyl-5,6,7,8-tetrahydro4-chloro-pyrido[3,4-d]pyrimidine hydrochloride

7-Benzyl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyrimidin-4-one hydrochloride Suppliers

Global Suppliers ( 133)

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Boyle Chemical Co., Ltd.		sales@boylechem.com	China	2915	55
Carbott PharmTech Inc.	0535-6385396	info@carbottpharm.com	China	996	56
Capot Chemical Co., Ltd	+86 (0) 571 85 58 67 18		China	18187	66
JinYan Chemicals(ShangHai) Co.,Ltd.	13817811078	sales@jingyan-chemical.com	China	9963	60
Shangchem Co., Ltd.	+86-21-68182121		China	881	52
Pure Chemistry Scientific Inc.	001-857-928-2050 or 1-888-588-9418	sales@chemreagents.com	United States	10174	62
China Langchem Inc.	0086-21-58956006		China	7798	57
Shanghai Topbiochem Technology Co., Ltd	+86-21-60341587	sales@topbiochem.com	China	6166	58
SuZhou ShiYa Biopharmaceuticals, Inc.	86(512)5235 8471 17715136450	sales@shiyabiopharm.com	China	4167	58
Shanghai Aladdin Bio-Chem Technology Co.,LTD	400-6206333 13167063860	anhua.mao@aladdin-e.com	China	29977	65

Supplier	Advantage
Shanghai Boyle Chemical Co., Ltd.	55
Carbott PharmTech Inc.	56
Capot Chemical Co., Ltd	66
JinYan Chemicals(ShangHai) Co.,Ltd.	60
Shangchem Co., Ltd.	52
Pure Chemistry Scientific Inc.	62
China Langchem Inc.	57
Shanghai Topbiochem Technology Co., Ltd	58
SuZhou ShiYa Biopharmaceuticals, Inc.	58
Shanghai Aladdin Bio-Chem Technology Co.,LTD	65

View Latest Price from 7-Benzyl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyrimidin-4-one hydrochloride manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-06-25	7-BENZYL-5,6,7,8-TETRAHYDRO-3H-PYRIDO[3,4-D]PYRIMIDIN-4-ONE HYDROCHLORIDE 62458-96-2	$1.10	1g	99.0% min	100 tons min	Shaanxi Dideu Medichem Co. Ltd
	2019-09-02	7-BENZYL-5,6,7,8-TETRAHYDRO-3H-PYRIDO[3,4-D]PYRIMIDIN-4-ONE HYDROCHLORIDE 62458-96-2	$1.00	1KG	≥98%	200KG	Career Henan Chemical Co

7-BENZYL-5,6,7,8-TETRAHYDRO-3H-PYRIDO[3,4-D]PYRIMIDIN-4-ONE HYDROCHLORIDE
62458-96-2
$1.10
99.0% min
Shaanxi Dideu Medichem Co. Ltd

7-BENZYL-5,6,7,8-TETRAHYDRO-3H-PYRIDO[3,4-D]PYRIMIDIN-4-ONE HYDROCHLORIDE
62458-96-2
$1.00
≥98%
Career Henan Chemical Co

7-Benzyl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyrimidin-4-one hydrochloride Spectrum

7-BENZYL-5,6,7,8-TETRAHYDRO-3H-PYRIDO[3,4-D]PYRIMIDIN-4-ONE HYDROCHLORIDE(62458-96-2)¹HNMR

62458-96-2 (7-Benzyl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyrimidin-4-one hydrochloride) Related Search:

Tetryzoline 7-Benzyl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyrimidin-4-one hydrochloride 1-Benzyl-4-methyl-1,2,3,6-tetrahydro-pyridine tert-butyl 4-oxo-3,4,5,6-tetrahydropyrido[3,4-d]pyriMidine-7(8H)-carboxylate 7-Benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione

Pyrido[3,4-d]pyriMidin-4(1H)-one, 5,6,7,8-tetrahydro-7-(phenylMethyl)-, Monohydrochloride

1of2

7-benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4(3H)-one 7-benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4(4aH)-one 5,6,7,8-Tetrahydro-7-(phenylmethyl)pyrido[3,4-d]pyrimidin-4(4aH)-one 4-d]pyriMidin-4(4aH)-one 7-benzyl-5 7-benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyriMidin-4-ol 7-benzyl-3H,4H,5H,6H,7H,8H-pyrido[3,4-d]pyriMidin-4-one 7-benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyriMidin-4(3H)-one hydrochloride 7-Benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4(3H) 5,6,7,8-Tetrahydro-7-(phenylmethyl)pyrido[3,4-d]pyrimidin-4( Pyrido[3,4-d]pyrimidin-4(4aH)-one, 5,6,7,8-tetrahydro-7-(phenylmethyl)- 7-BENZYL-5,6,7,8-TETRAHYDROPYRIDO[3,4-D]PYRIMIDIN-4(3H)-ONE HCL Pyrido[3,4-d]pyrimidin-4(3H)-one,5,6,7,8-tetrahydro-7-(phenylmethyl)- 7-Benzyl-5,6,7,8-tetrahydro-4aH-pyrido[3,4-d]pyrimidin-4-one 7-BENZYL-5,6,7,8-TETRAHYDRO-3H-PYRIDO[3,4-D]PYRIMIDIN-4-ONE HYDROCHLORIDE ISO 9001：2015 REACH -BENZYL-5,6,7,8-TETRAHYDRO-3H-PYRIDO[3,4-D]PYRIMIDIN-4-ONE HYDROCHLORIDE 7-benzyl-5,6,7,8-Ttetrahydropyridinebenzo[3,4-d]pyrimidine-4(3H)-one 7-Benzyl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyrimidin-4-one hydrochloride 62458-96-2 MFCD08458225 oldold CHIRAL CHEMICALS