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L-CYSTATHIONINE

CAS No.
56-88-2
Chemical Name:
L-CYSTATHIONINE
Synonyms
L-CYSTATHIONINE;L(+)CYSTATHIONINE;CYSTATHIONINE, L-;L-Cystathionine (P);L-Cystathionine Standard;L-Cystathionine;L-CYSTATHIONINE, >= 98% (TLC);CYSTATHIONINE, L-(DS)(REQUEST QUOTE);(2R,7S)-2,7-Diamino-4-thiaoctanedioic acid;[R]-S-[2-AMINO-2-CARBOXYETHYL]-L-HOMOCYSTEINE
CBNumber:
CB6446239
Molecular Formula:
C7H14N2O4S
Molecular Weight:
222.26
MDL Number:
MFCD00036685
MOL File:
56-88-2.mol
MSDS File:
SDS
Last updated:2025-12-29 14:06:09
Product description Number Pack Size Price
L-Cystathionine ≥98% (TLC) C7505 10mg $116
L-Cystathionine ≥98% (TLC) C7505 50mg $407
L-(+)-Cystathionine ≥98% 16061 5mg $46
L-(+)-Cystathionine ≥98% 16061 10mg $74
L-Cystathionine ≥98% (TLC) C7505 250mg $1620
More product size

L-CYSTATHIONINE Properties

Melting point 312
alpha D20 +23.7° (1N HCl)
Density 1.430±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. -20°C
solubility Aqueous Acid (Slightly)
form Solid
Boiling point 481.0±45.0 °C(Predicted)
pka 2.08±0.10(Predicted)
color White to Off-White
optical activity +26.425 (1 mol dm-3 HCl)
Merck 13,2807
BRN 2505200
FDA UNII 375YFJ481O
UNSPSC Code 12352209
NACRES NA.26

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P271-P280
WGK Germany  3
10-21
HS Code  29309090
NFPA 704
0
2 0

L-CYSTATHIONINE price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C7505 L-Cystathionine ≥98% (TLC) 56-88-2 10mg $116 2025-07-31 Buy
Sigma-Aldrich C7505 L-Cystathionine ≥98% (TLC) 56-88-2 50mg $407 2025-07-31 Buy
Cayman Chemical 16061 L-(+)-Cystathionine ≥98% 56-88-2 5mg $46 2024-03-01 Buy
Cayman Chemical 16061 L-(+)-Cystathionine ≥98% 56-88-2 10mg $74 2024-03-01 Buy
Sigma-Aldrich C7505 L-Cystathionine ≥98% (TLC) 56-88-2 250mg $1620 2025-07-31 Buy
Product number Packaging Price Buy
C7505 10mg $116 Buy
C7505 50mg $407 Buy
16061 5mg $46 Buy
16061 10mg $74 Buy
C7505 250mg $1620 Buy

L-CYSTATHIONINE Chemical Properties,Uses,Production

Description

L-(+)-Cystathionine is a dipeptide formed by serine and homocysteine. Transsulfuration of methionine yields homocysteine, which combines with serine to form this precursor of cysteine. L-(+)-Cystathionine is largely expressed in the mammalian brain and deficiency can indicate the presence of metabolic disorders such as cystathioninuria.

Chemical Properties

White Crystalline Solid

Uses

Intermediate in transsulfuration whereby the mammal transfers the sulfur of methionine via homocysteine to cysteine

Uses

L-Cystathionine has been used in ultra-performance liquid chromatography for the validation of cystathionine and the correlation of its abundance with vertebrate metamorphosis. It has also been used as an inhibitor of sinusoidal GSH (glutathione) carrier to signify that thiol redox state imbalance is associated with the modulation of autophagy in carcinoma cells.

Definition

ChEBI: L-cystathionine is a modified amino acid generated by enzymic means from L-homocysteine and L-serine. It has a role as a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a tautomer of a L-cystathionine dizwitterion.

Biochem/physiol Actions

L-Cystathionine is an intermediate in the biosynthesis of L-cysteine and methionine. It is used as a substrate to differentiate and analyze cystathionine γ-lyase(s). L-Cystathionine is an important non-protein amino acid and is associated with metabolic disorders. In recent studies, L-cystathionine is believed to be the precursor of cyclic imino acid cyclothionine. Cystathioninuria is characterized with imino acid cyclothionine excretion in the urine.

Purification Methods

S,S-Cystathionine is purified by converting it to the HCl salt in 20% HCl and carefully basifying with aqueous NH3 until separation is complete. Filter it off and dry it in a vacuum. It forms prisms from H2O. The dibenzoyl derivative has m 229o (from EtOH). [IR: Greenstein & Winitz Chemistry of the Amino Acids (J Wiley) Vol 3 p2690 1961 and Tallan et al. J Biol Chem 230 707 1958, Synthesis: du Vigneaud et al. J Biol Chem 143 59 1942, Anslow et al. J Biol Chem 166 39 1946.] [Prepn: Weiss & Stekol J Am Chem Soc 73 2497 1951; see also du Vigneaud et al. J Biol Chem 143 60 1942, Biological synthesis: Greenberg Methods Enzymol 5 943 1962, Beilstein 4 IV 3197.]

References

[1] FINKELSTEIN J D. The metabolism of homocysteine: pathways and regulation.[J]. European Journal of Pediatrics, 1998, 157 Suppl 2: S40-4. DOI: 10.1007/pl00014300
[2] TAKUYA NISHI. Accumulation of L-cystathionine by an Escherichia coli mutant deficient in cystathionine beta-lyase.[J]. Journal of bioscience and bioengineering, 2002, 94 2: 178-181. DOI: 10.1263/jbb.94.178

L-CYSTATHIONINE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 139)Suppliers
Supplier Tel Email Country ProdList Advantage
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29843 58
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32436 58
Dayang Chem (Hangzhou) Co.,Ltd.
+86-0571-88938639 +8617705817739 info@dycnchem.com China 52846 58
Nextpeptide Inc
+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19908 58
Alfa Chemistry
+1-5166625404; Info@alfa-chemistry.com United States 20405 58
TargetMol Chemicals Inc.
+1-781-999-5354; support@targetmol.com United States 39035 58
GIHI CHEMICALS CO.,LIMITED
+86-571-86217390; +8618058761490 info@gihichemicals.com China 49944 58
HANGZHOU LEAP CHEM CO., LTD.
+86-571-87711850 market18@leapchem.com China 43339 58
Aladdin Scientific
tp@aladdinsci.com United States 57505 58
XIAMEN AMITY INDUSTRY AND TRADE CO., LTD.
+8618950047208 ellena@amitychem.com China 43416 58

View Lastest Price from L-CYSTATHIONINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
L-Cystathionine pictures 2025-12-29 L-Cystathionine
56-88-2
US $98.00-142.00 / mg 98.00% 10g TargetMol Chemicals Inc.
L-Cystathionine pictures 2025-12-29 L-Cystathionine
56-88-2
US $98.00-142.00 / mg 98.00% 10g TargetMol Chemicals Inc.
L-Cystathionine pictures 2019-07-06 L-Cystathionine
56-88-2
US $1.00 / kg 1kg 95%-99% 1000kg Career Henan Chemical Co
CYSTATHIONINE, L- L(+)CYSTATHIONINE L-CYSTATHIONINE L-CYSTATHIONINE, >= 98% (TLC) [R]-S-[2-AMINO-2-CARBOXYETHYL]-L-HOMOCYSTEINE (2S)-2-amino-4-[(2R)-2-amino-3-hydroxy-3-oxopropyl]sulfanylbutanoic acid L-Cystathionine,(R)-S-(2-Amino-2-carboxyethyl)-L-homocysteine (2S)-2-Amino-4-{[(2R)-2-amino-2-carboxyethyl]thio}butanoic acid [R-(R*,S*)]-2-AMino-4-[(2-aMino-2-carboxyethyl)thio]butanoic Acid S-[(2R)-2-AMino-2-carboxyethyl]-L-hoMocysteine CYSTATHIONINE, L-(DS)(REQUEST QUOTE) (2R,7S)-2,7-Diamino-4-thiaoctanedioic acid S-[(R)-2-Amino-2-carboxyethyl]-L-homocysteine L-Homocysteine, S-[(2R)-2-amino-2-carboxyethyl]- L-Cystathionine Standard L-Cystathionine (P) L-Cystathionine 56-88-2 Amino Acid Library BioChemical Metabolic Libraries Metabolomics Cysteine Derivatives Peptide Synthesis Specialty Synthesis Unnatural Amino Acid Derivatives Amino Acids 13C, 2H, 15N Amino Acids & Derivatives Intermediates Sulfur & Selenium Compounds