L-CYSTATHIONINE
- CAS No.
- 56-88-2
- Chemical Name:
- L-CYSTATHIONINE
- Synonyms
- L-CYSTATHIONINE;L(+)CYSTATHIONINE;CYSTATHIONINE, L-;L-Cystathionine (P);L-Cystathionine Standard;
L -Cystathionine;L-CYSTATHIONINE, >= 98% (TLC);CYSTATHIONINE, L-(DS)(REQUEST QUOTE);(2R,7S)-2,7-Diamino-4-thiaoctanedioic acid;[R]-S-[2-AMINO-2-CARBOXYETHYL]-L-HOMOCYSTEINE
- CBNumber:
- CB6446239
- Molecular Formula:
- C7H14N2O4S
- Molecular Weight:
- 222.26
- MDL Number:
- MFCD00036685
- MOL File:
- 56-88-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 312 |
|---|---|
| alpha | D20 +23.7° (1N HCl) |
| Density | 1.430±0.06 g/cm3 (20 ºC 760 Torr) |
| storage temp. | -20°C |
| solubility | Aqueous Acid (Slightly) |
| form | Solid |
| Boiling point | 481.0±45.0 °C(Predicted) |
| pka | 2.08±0.10(Predicted) |
| color | White to Off-White |
| optical activity | +26.425 (1 mol dm-3 HCl) |
| Merck | 13,2807 |
| BRN | 2505200 |
| InChI | 1S/C7H14N2O4S/c8-4(6(10)11)1-2-14-3-5(9)7(12)13/h4-5H,1-3,8-9H2,(H,10,11)(H,12,13)/t4-,5-/m0/s1 |
| InChIKey | ILRYLPWNYFXEMH-WHFBIAKZSA-N |
| SMILES | N[C@@H](CCSC[C@H](N)C(O)=O)C(O)=O |
| FDA UNII | 375YFJ481O |
| UNSPSC Code | 12352209 |
| NACRES | NA.26 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P271-P280 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10-21 | |||||||||
| HS Code | 29309090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
L-CYSTATHIONINE price More Price(44)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C7505 | L-Cystathionine ≥98% (TLC) | 56-88-2 | 10mg | $123 | 2026-04-30 | Buy |
| Sigma-Aldrich | C7505 | L-Cystathionine ≥98% (TLC) | 56-88-2 | 50mg | $433 | 2026-04-30 | Buy |
| Cayman Chemical | 16061 | L-(+)-Cystathionine ≥98% | 56-88-2 | 5mg | $75 | 2026-04-30 | Buy |
| Cayman Chemical | 16061 | L-(+)-Cystathionine ≥98% | 56-88-2 | 10mg | $120 | 2026-04-30 | Buy |
| Cayman Chemical | 16061 | L-(+)-Cystathionine ≥98% | 56-88-2 | 25mg | $281 | 2026-04-30 | Buy |
L-CYSTATHIONINE Chemical Properties,Uses,Production
Description
L-
Chemical Properties
White Crystalline Solid
Uses
Intermediate in transsulfuration whereby the mammal transfers the sulfur of methionine via homocysteine to cysteine
Uses
L-Cystathionine has been used in ultra-performance liquid chromatography for the validation of cystathionine and the correlation of its abundance with vertebrate metamorphosis. It has also been used as an inhibitor of sinusoidal GSH (glutathione) carrier to signify that thiol redox state imbalance is associated with the modulation of autophagy in carcinoma cells.
Definition
ChEBI: L-cystathionine is a modified amino acid generated by enzymic means from L-homocysteine and L-serine. It has a role as a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a tautomer of a L-cystathionine dizwitterion.
Biochem/physiol Actions
L-Cystathionine is an intermediate in the biosynthesis of L-cysteine and methionine. It is used as a substrate to differentiate and analyze cystathionine γ-lyase(s). L-Cystathionine is an important non-protein amino acid and is associated with metabolic disorders. In recent studies, L-cystathionine is believed to be the precursor of cyclic imino acid cyclothionine. Cystathioninuria is characterized with imino acid cyclothionine excretion in the urine.
Purification Methods
S,S-Cystathionine is purified by converting it to the HCl salt in 20% HCl and carefully basifying with aqueous NH3 until separation is complete. Filter it off and dry it in a vacuum. It forms prisms from H2O. The dibenzoyl derivative has m 229o (from EtOH). [IR: Greenstein & Winitz Chemistry of the Amino Acids (J Wiley) Vol 3 p2690 1961 and Tallan et al. J Biol Chem 230 707 1958, Synthesis: du Vigneaud et al. J Biol Chem 143 59 1942, Anslow et al. J Biol Chem 166 39 1946.] [Prepn: Weiss & Stekol J Am Chem Soc 73 2497 1951; see also du Vigneaud et al. J Biol Chem 143 60 1942, Biological synthesis: Greenberg Methods Enzymol 5 943 1962, Beilstein 4 IV 3197.]
References
[1] FINKELSTEIN J D. The metabolism of homocysteine: pathways and regulation.[J]. European Journal of Pediatrics, 1998, 157 Suppl 2: S40-4. DOI: 10.1007/pl00014300
[2] TAKUYA NISHI. Accumulation of L-cystathionine by an Escherichia coli mutant deficient in cystathionine beta-lyase.[J]. Journal of bioscience and bioengineering, 2002, 94 2: 178-181. DOI: 10.1263/jbb.94.178
L-CYSTATHIONINE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| China DongFan Chemical Co.,LTD | 86-0571-85151182 | China | 5681 | 66 | |
| Wuhan Taiyicheng Biopharmaceutical Co., Ltd. | 027-88320699 | tycshyy@126.com | China | 297 | 66 |
| The future of Shanghai Industrial Co., Ltd. | 021-61552785 | sales@shshiji.com | China | 9531 | 55 |
| Shanghai TaoSu Biochemical Technology Co., Ltd. | 021-33632979 | info@tsbiochem.com | China | 8039 | 58 |
| Shanghai BeiZhuo Biotech Co., Ltd. | 021-61119791,13386096464 | bzswkf@foxmail.com | China | 3916 | 50 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7717 | 56 |
| Wuxi Zhongkun Biochemical Technology Co., Ltd. | 0510-85629785 18013409632; | sales@reading-chemicals.com | China | 15165 | 58 |
View Lastest Price from L-CYSTATHIONINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-15 | L-Cystathionine
56-88-2
|
$39.00-142.00 | 96.43% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-07-15 | L-Cystathionine
56-88-2
|
$39.00-142.00 | 96.43% | 10g | TargetMol Chemicals Inc. | ||
 |
2019-07-06 | L-Cystathionine
56-88-2
|
$1.00 | 1kg | 95%-99% | 1000kg | Career Henan Chemical Co |
-
- L-Cystathionine
56-88-2
- $39.00-142.00
- 96.43%
- TargetMol Chemicals Inc.
-
- L-Cystathionine
56-88-2
- $39.00-142.00
- 96.43%
- TargetMol Chemicals Inc.
-
- L-Cystathionine
56-88-2
- $1.00
- 95%-99%
- Career Henan Chemical Co
56-88-2(L-CYSTATHIONINE)Related Search:
1of4
