Pyrazine-2-carboxamidine hydrochloride
- CAS No.
- 138588-41-7
- Chemical Name:
- Pyrazine-2-carboxamidine hydrochloride
- Synonyms
- PYRAZINE-2-CARBOXIMIDAMIDE HYDROCHLORIDE;AIDS070607;AIDS-070607;BUTTPARK 32\03-57;pyrazine-2-carboximidamide;PYRAZINE-2-CARBOXAMIDINE HCL;pyrazinamidine hydrochloride;2-pyrazinecarboxamidine hydrochloride;Pyrazine-2-carboxamidine hydrochloride;Pyrazine-2-carboximidamide monohydrochloride
- CBNumber:
- CB6457613
- Molecular Formula:
- C5H7ClN4
- Molecular Weight:
- 158.59
- MDL Number:
- MFCD05663360
- MOL File:
- 138588-41-7.mol
- MSDS File:
- SDS
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
|---|---|
| form | solid |
| color | White |
| CAS DataBase Reference | 138588-41-7(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H302-H319-H335 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501 |
| Hazard Codes | Xi,Xn |
| Risk Statements | 22 |
| HazardClass | IRRITANT |
| HS Code | 2933998090 |
Pyrazine-2-carboxamidine hydrochloride price More Price(43)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS30820 | Pyrazine-2-carboximidamide hydrochloride 97% | 138588-41-7 | 1g | $21 | 2026-06-04 | Buy |
| Activate Scientific | AS30820 | Pyrazine-2-carboximidamide hydrochloride 97% | 138588-41-7 | 5g | $45 | 2026-06-04 | Buy |
| Apolloscientific | OR3402 | Pyrazine-2-carboxamidine hydrochloride 98% | 138588-41-7 | 1g | $21 | 2026-06-04 | Buy |
| Activate Scientific | AS30820 | Pyrazine-2-carboximidamide hydrochloride 97% | 138588-41-7 | 25g | $78 | 2026-06-04 | Buy |
| Apolloscientific | OR3402 | Pyrazine-2-carboxamidine hydrochloride 98% | 138588-41-7 | 5g | $33 | 2026-06-04 | Buy |
Pyrazine-2-carboxamidine hydrochloride Chemical Properties,Uses,Production
Synthesis
19847-12-2
138588-41-7
The general procedure for the synthesis of 2-pyrazinamidine hydrochloride from 2-cyanopyrazine was as follows: 2-cyanopyrazine (1.00 kg, 9.53 mol) was slowly added to a solution of sodium methanol (NaOCH3, 51.4 g, 0.952 mol) in methanol (3800 mL) at room temperature. The reaction mixture was heated to 30 °C and stirred for 6 hours. Upon completion of the reaction, the mixture was cooled to 25 °C, followed by the addition of ammonium chloride (NH4Cl, 572 g, 10.5 mol). Stirring of the reaction mixture was continued for 22 hours. At the end of the reaction, methyl tert-butyl ether (4000 mL) was added and stirred for 15 minutes to promote solid formation. The solid product was collected by filtration and washed with methyl tert-butyl ether (2 x 1000 mL). Finally, the product was dried at 40 °C, 0-10 mmHg for 17 h to give the white solid product 2-pyrazinamidine hydrochloride (1435 g) in 95% yield and 95% purity by HPLC.1H NMR (DMSO-D6) data were as follows: δ 9.7 (broad single peak, 3H), 9.49 (double peak, 1H, J=1.5Hz), 9.04 (multiple peaks, 1H), 8.93 (multiple peaks, 1H), 9.04 (multiple peaks, 1H), 8.93 (multiple peaks 1H), 8.93 (triple peak, 1H, J=1.5Hz).
References
[1] Patent: US2006/281760, 2006, A1. Location in patent: Page/Page column 5; 8
[2] Bioorganic and Medicinal Chemistry, 2009, vol. 17, # 1, p. 111 - 118
[3] Patent: US2005/75357, 2005, A1. Location in patent: Page/Page column 35
[4] Patent: WO2005/79798, 2005, A1. Location in patent: Page/Page column 150
[5] Bioorganic and Medicinal Chemistry Letters, 2010, vol. 20, # 1, p. 299 - 301
Pyrazine-2-carboxamidine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Shanghai Ennopharm Co., Ltd. | +86 (21) 6435-5022 | China | 4263 | 65 | |
| Shanghai yirong biology science and technology co., ltd | 18049974220 | 3060526242@qq.com | China | 999 | 60 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 18201 | 56 |
| Acesys Pharmatech | 18860950986 | tangmanman@zenjipharma.com | China | 1731 | 55 |
View Lastest Price from Pyrazine-2-carboxamidine hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-03-16 | PYRAZINE-2-CARBOXAMIDINE HYDROCHLORIDE
138588-41-7
|
$3.00 | 1KG | 98% | 100KG | Career Henan Chemical Co |
-
- PYRAZINE-2-CARBOXAMIDINE HYDROCHLORIDE
138588-41-7
- $3.00
- 98%
- Career Henan Chemical Co
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