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PYRAZINE-2-CARBOXAMIDINE HYDROCHLORIDE

CAS No.
138588-41-7
Chemical Name:
PYRAZINE-2-CARBOXAMIDINE HYDROCHLORIDE
Synonyms
PYRAZINE-2-CARBOXIMIDAMIDE HYDROCHLORIDE;AIDS070607;AIDS-070607;BUTTPARK 32\03-57;pyrazine-2-carboximidamide;pyrazinamidine hydrochloride;PYRAZINE-2-CARBOXAMIDINE HCL;2-pyrazinecarboxamidine hydrochloride;PYRAZINE-2-CARBOXAMIDINE HYDROCHLORIDE;Pyrazine-2-carboximidamide monohydrochloride
CBNumber:
CB6457613
Molecular Formula:
C5H7ClN4
Molecular Weight:
158.59
MDL Number:
MFCD05663360
MOL File:
138588-41-7.mol
MSDS File:
SDS
Last updated:2026-05-28 02:17:54
Product description Number Pack Size Price
Pyrazine-2-carboximidamide hydrochloride 97% AS30820 1g $21
Pyrazine-2-carboximidamide hydrochloride 97% AS30820 5g $45
Pyrazine-2-carboxamidine hydrochloride 98% OR3402 1g $21
Pyrazine-2-carboximidamide hydrochloride 97% AS30820 25g $78
Pyrazine-2-carboxamidine hydrochloride 98% OR3402 5g $33
More product size

PYRAZINE-2-CARBOXAMIDINE HYDROCHLORIDE Properties

storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form solid
color White
CAS DataBase Reference 138588-41-7(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H302-H319-H335
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501
Hazard Codes  Xi,Xn
Risk Statements  22
HazardClass  IRRITANT
HS Code  2933998090

PYRAZINE-2-CARBOXAMIDINE HYDROCHLORIDE price More Price(56)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS30820 Pyrazine-2-carboximidamide hydrochloride 97% 138588-41-7 1g $21 2026-06-04 Buy
Activate Scientific AS30820 Pyrazine-2-carboximidamide hydrochloride 97% 138588-41-7 5g $45 2026-06-04 Buy
Apolloscientific OR3402 Pyrazine-2-carboxamidine hydrochloride 98% 138588-41-7 1g $21 2026-06-04 Buy
Activate Scientific AS30820 Pyrazine-2-carboximidamide hydrochloride 97% 138588-41-7 25g $78 2026-06-04 Buy
Apolloscientific OR3402 Pyrazine-2-carboxamidine hydrochloride 98% 138588-41-7 5g $33 2026-06-04 Buy
Product number Packaging Price Buy
AS30820 1g $21 Buy
AS30820 5g $45 Buy
OR3402 1g $21 Buy
AS30820 25g $78 Buy
OR3402 5g $33 Buy

PYRAZINE-2-CARBOXAMIDINE HYDROCHLORIDE Chemical Properties,Uses,Production

Synthesis

Pyrazinecarbonitrile

19847-12-2

PYRAZINE-2-CARBOXAMIDINE HYDROCHLORIDE

138588-41-7

The general procedure for the synthesis of 2-pyrazinamidine hydrochloride from 2-cyanopyrazine was as follows: 2-cyanopyrazine (1.00 kg, 9.53 mol) was slowly added to a solution of sodium methanol (NaOCH3, 51.4 g, 0.952 mol) in methanol (3800 mL) at room temperature. The reaction mixture was heated to 30 °C and stirred for 6 hours. Upon completion of the reaction, the mixture was cooled to 25 °C, followed by the addition of ammonium chloride (NH4Cl, 572 g, 10.5 mol). Stirring of the reaction mixture was continued for 22 hours. At the end of the reaction, methyl tert-butyl ether (4000 mL) was added and stirred for 15 minutes to promote solid formation. The solid product was collected by filtration and washed with methyl tert-butyl ether (2 x 1000 mL). Finally, the product was dried at 40 °C, 0-10 mmHg for 17 h to give the white solid product 2-pyrazinamidine hydrochloride (1435 g) in 95% yield and 95% purity by HPLC.1H NMR (DMSO-D6) data were as follows: δ 9.7 (broad single peak, 3H), 9.49 (double peak, 1H, J=1.5Hz), 9.04 (multiple peaks, 1H), 8.93 (multiple peaks, 1H), 9.04 (multiple peaks, 1H), 8.93 (multiple peaks 1H), 8.93 (triple peak, 1H, J=1.5Hz).

References

[1] Patent: US2006/281760, 2006, A1. Location in patent: Page/Page column 5; 8
[2] Bioorganic and Medicinal Chemistry, 2009, vol. 17, # 1, p. 111 - 118
[3] Patent: US2005/75357, 2005, A1. Location in patent: Page/Page column 35
[4] Patent: WO2005/79798, 2005, A1. Location in patent: Page/Page column 150
[5] Bioorganic and Medicinal Chemistry Letters, 2010, vol. 20, # 1, p. 299 - 301

19847-12-2
138588-41-7
Synthesis of PYRAZINE-2-CARBOXAMIDINE HYDROCHLORIDE from Pyrazinecarbonitrile

PYRAZINE-2-CARBOXAMIDINE HYDROCHLORIDE Preparation Products And Raw materials

Global( 97)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29640 60
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49979 58
career henan chemical co
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Win-Win chemical CO., Limited
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Dayang Chem (Hangzhou) Co.,Ltd.
+86-0571-88938639 +8617705817739 info@dycnchem.com China 52704 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418684 +8618949823763 sales@tnjchem.com China 25356 58
PT CHEM GROUP LIMITED
+86-85511178; peter68@ptchemgroup.com China 35425 58
GIHI CHEMICALS CO.,LIMITED
+86-571-86217390; +8618058761490 info@gihichemicals.com China 49892 58

View Lastest Price from PYRAZINE-2-CARBOXAMIDINE HYDROCHLORIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
PYRAZINE-2-CARBOXAMIDINE HYDROCHLORIDE pictures 2020-03-16 PYRAZINE-2-CARBOXAMIDINE HYDROCHLORIDE
138588-41-7
$3.00 1KG 98% 100KG Career Henan Chemical Co

PYRAZINE-2-CARBOXAMIDINE HYDROCHLORIDE Spectrum

PYRAZINE-2-CARBOXAMIDINE HCL PYRAZINE-2-CARBOXAMIDINE HYDROCHLORIDE BUTTPARK 32\03-57 pyrazine-2-carboximidamide Pyrazine-2-carboximidamide monohydrochloride pyrazinamidine hydrochloride Pyrazine-2-carboximidamide hydrochloride, 2-Carbamimidoyl-1,4-diazine hydrochloride (amino-pyrazin-2-yl-methylene)ammonium chloride (amino-pyrazin-2-ylmethylidene)azanium chloride (amino-pyrazin-2-yl-methylidene)azanium chloride [amino-(2-pyrazinyl)methylene]ammonium chloride 2-pyrazinecarboxamidine hydrochloride AIDS070607 AIDS-070607 2-Pyrazinecarboximidamide, hydrochloride (1:1) PYRAZINE-2-CARBOXIMIDAMIDE HYDROCHLORIDE 138588-41-7 Pyrazines, Pyrimidines & Pyridazines pharmacetical Pyrazines, Pyrimidines & Pyridazines Pyrazine