ChemicalBook >> CAS DataBase List >>6,8-Difluoro-7-hydroxy-4-methylcoumarin

6,8-Difluoro-7-hydroxy-4-methylcoumarin

CAS No.
215868-23-8
Chemical Name:
6,8-Difluoro-7-hydroxy-4-methylcoumarin
Synonyms
6,8-Difluoro-7-hydroxy-4-methyl-2h-chromen-2-one;DiFMU;Hymecromone Impurity 5;6,8-Difluoro-7-hydroxy-4-methylcoumarin;6,8-Difluoro-7-hydroxy-4-methylcoumarin (DIFMU);6,8-Difluoro-7-hydroxy-4-methyl-2H-1-benzopyran-2-one;2H-1-Benzopyran-2-one, 6,8-difluoro-7-hydroxy-4-methyl-
CBNumber:
CB6465713
Molecular Formula:
C10H6F2O3
Molecular Weight:
212.15
MDL Number:
MFCD01073675
MOL File:
Mol file
MSDS File:
SDS
Last updated:2026-09-12 18:54:16

6,8-Difluoro-7-hydroxy-4-methylcoumarin Properties

Melting point 213-215°C
Boiling point 332.3±42.0 °C(Predicted)
Density 1.494±0.06 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Insoluble in water; soluble in chloroform, N,N-dimethylformamide, dimethyl sulfoxide
pka 4.7, (at 22℃) (calcd.) 5.50 ± 0.20, most acidic, temperature: 25 °C
form Off-White to Pale Yellow Soild
color Colorless needles; white solid
λmax 358 nm (Buffers pH 10.0, pH 9.0)
Stability Hygroscopic
Major Application Detecting/quantifying/measuring metals (beryllium, chromium, lead)
Biological Applications Amplifying/detectingnucleic acid sequences; analyzing peptides, sugarchains; detecting bacteria; detecting/quantifyingnucleic acids; a substrate for measuring acylprotein thioesterase (APT) activity,, α-amylaseactivity, aryl sulfatases activity, β-galactosidasesactivity,,, guanidinobenzoatase activity, β-lactamaseactivity, lipase activity, phosphatases activity,,phospholipase LYPLAL activity, protein kinasesactivity, xylanase activity; diagnosing/treatingtraumatic brain injury; treating amyloidogenic disease;as temperature sensor,
InChIKey LLENVBUPWUQAGL-UHFFFAOYSA-N
SMILES FC1=C2C(C(C)=CC(O2)=O)=CC(F)=C1O
UNSPSC Code 12352200
NACRES NA.21

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)
GHS06
Signal word  Danger
Hazard statements  H301-H317
Precautionary statements  P261-P264-P272-P280-P301+P310-P302+P352
WGK Germany  WGK 3
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Acute Tox. 3 Oral
Skin Sens. 1

6,8-Difluoro-7-hydroxy-4-methylcoumarin price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 36017 6,8-Difluoro-7-hydroxy-4-methylcoumarin ≥98% 215868-23-8 1mg $32 2026-04-30 Buy
Cayman Chemical 36017 6,8-Difluoro-7-hydroxy-4-methylcoumarin ≥98% 215868-23-8 5mg $102 2026-04-30 Buy
Cayman Chemical 36017 6,8-Difluoro-7-hydroxy-4-methylcoumarin ≥98% 215868-23-8 10mg $172 2026-04-30 Buy
Cayman Chemical 36017 6,8-Difluoro-7-hydroxy-4-methylcoumarin ≥98% 215868-23-8 25mg $349 2026-04-30 Buy
Usbiological 272967 6,8-Difluoro-7-hydroxy-4-methylcoumarin 215868-23-8 1mg $325 2026-06-03 Buy
Product number Packaging Price Buy
36017 1mg $32 Buy
36017 5mg $102 Buy
36017 10mg $172 Buy
36017 25mg $349 Buy
272967 1mg $325 Buy

6,8-Difluoro-7-hydroxy-4-methylcoumarin Chemical Properties, Uses, Production

Uses

6,8-Difluoro-7-hydroxy-4-methylcoumarin (DIFMU) was used for the diagnostic detection of natural killer cell-activity.

Definition

ChEBI: 6,8-difluoro-7-hydroxy-4-methylcoumarin is a hydroxycoumarin. It has a role as a fluorochrome.

Biological Activity

Fluorescent product of hydrolysis of fluorogenic phosphatase substrate DiFMUP.



DiFMU is a fluorescent product of hydrolysis of fluorogenic phosphatase substrate DiFMUP. DiFMU excitation wavelength is 358nm and emission can be detected at 455 nm.

6,8-Difluoro-7-hydroxy-4-methylcoumarin Preparation Products And Raw materials

Raw materials

Preparation Products

6,8-Difluoro-7-hydroxy-4-methylcoumarin Suppliers

Global Suppliers ( 18)
Supplier Tel Email Country ProdList Advantage
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656 greensnown@163.com China 9883 50
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 9787 55
Shenzhen GeneSeqTools Bioscience & Technology Co. Ltd. 0755-23251735 13302967066 sales@geneseqtools.com China 1466 58
VladaChem GmbH +49-7246-3082843 +86-18411632868 info@vladachem.de Germany 1854 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
Bejing Famous Pharmaceutical Technology Co., Ltd. 15811073878 2559355526@qq.com China 10680 58
Shanghai Haohong Scientific Co., Ltd. 400-8210725 4008210725 malulu@leyan.com China 39718 58
Shanghai Beiwanta Biotechnology Co., Ltd. 021-67187366 19901745723 info@bwtlab.com China 9880 58
TargetMol 400-821-0310 15002144251 xuexiang.shao@tsbiochem.com China 29128 58
6,8-Difluoro-7-hydroxy-4-methyl-2H-1-benzopyran-2-one 2H-1-Benzopyran-2-one, 6,8-difluoro-7-hydroxy-4-methyl- 6,8-Difluoro-7-hydroxy-4-methylcoumarin (DIFMU) Hymecromone Impurity 5 DiFMU 6,8-Difluoro-7-hydroxy-4-methyl-2h-chromen-2-one 6,8-Difluoro-7-hydroxy-4-methylcoumarin 215868-23-8