6,8-Difluoro-7-hydroxy-4-methylcoumarin
- CAS No.
- 215868-23-8
- Chemical Name:
- 6,8-Difluoro-7-hydroxy-4-methylcoumarin
- Synonyms
- 6,8-Difluoro-7-hydroxy-4-methyl-2h-chromen-2-one;DiFMU;Hymecromone Impurity 5;6,8-Difluoro-7-hydroxy-4-methylcoumarin;6,8-Difluoro-7-hydroxy-4-methylcoumarin (DIFMU);6,8-Difluoro-7-hydroxy-4-methyl-2H-1-benzopyran-2-one;2H-1-Benzopyran-2-one, 6,8-difluoro-7-hydroxy-4-methyl-
- CBNumber:
- CB6465713
- Molecular Formula:
- C10H6F2O3
- Molecular Weight:
- 212.15
- MDL Number:
- MFCD01073675
- MOL File:
- Mol file
- MSDS File:
- SDS
| Melting point | 213-215°C |
|---|---|
| Boiling point | 332.3±42.0 °C(Predicted) |
| Density | 1.494±0.06 g/cm3(Predicted) |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | Insoluble in water; soluble in chloroform, N,N-dimethylformamide, dimethyl sulfoxide |
| pka | 4.7, (at 22℃) (calcd.) 5.50 ± 0.20, most acidic, temperature: 25 °C |
| form | Off-White to Pale Yellow Soild |
| color | Colorless needles; white solid |
| λmax | 358 nm (Buffers pH 10.0, pH 9.0) |
| Stability | Hygroscopic |
| Major Application | Detecting/quantifying/measuring metals (beryllium, chromium, lead) |
| Biological Applications | Amplifying/detectingnucleic acid sequences; analyzing peptides, sugarchains; detecting bacteria; detecting/quantifyingnucleic acids; a substrate for measuring acylprotein thioesterase (APT) activity,, α-amylaseactivity, aryl sulfatases activity, β-galactosidasesactivity,,, guanidinobenzoatase activity, β-lactamaseactivity, lipase activity, phosphatases activity,,phospholipase LYPLAL activity, protein kinasesactivity, xylanase activity; diagnosing/treatingtraumatic brain injury; treating amyloidogenic disease;as temperature sensor, |
| InChIKey | LLENVBUPWUQAGL-UHFFFAOYSA-N |
| SMILES | FC1=C2C(C(C)=CC(O2)=O)=CC(F)=C1O |
| UNSPSC Code | 12352200 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301-H317 |
| Precautionary statements | P261-P264-P272-P280-P301+P310-P302+P352 |
| WGK Germany | WGK 3 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| Hazard Classifications | Acute Tox. 3 Oral Skin Sens. 1 |
6,8-Difluoro-7-hydroxy-4-methylcoumarin price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 36017 | 6,8-Difluoro-7-hydroxy-4-methylcoumarin ≥98% | 215868-23-8 | 1mg | $32 | 2026-04-30 | Buy |
| Cayman Chemical | 36017 | 6,8-Difluoro-7-hydroxy-4-methylcoumarin ≥98% | 215868-23-8 | 5mg | $102 | 2026-04-30 | Buy |
| Cayman Chemical | 36017 | 6,8-Difluoro-7-hydroxy-4-methylcoumarin ≥98% | 215868-23-8 | 10mg | $172 | 2026-04-30 | Buy |
| Cayman Chemical | 36017 | 6,8-Difluoro-7-hydroxy-4-methylcoumarin ≥98% | 215868-23-8 | 25mg | $349 | 2026-04-30 | Buy |
| Usbiological | 272967 | 6,8-Difluoro-7-hydroxy-4-methylcoumarin | 215868-23-8 | 1mg | $325 | 2026-06-03 | Buy |
6,8-Difluoro-7-hydroxy-4-methylcoumarin Chemical Properties, Uses, Production
Uses
6,8-Difluoro-7-hydroxy-4-methylcoumarin (DIFMU) was used for the diagnostic detection of natural killer cell-activity.
Definition
ChEBI: 6,8-difluoro-7-hydroxy-4-methylcoumarin is a hydroxycoumarin. It has a role as a fluorochrome.
Biological Activity
Fluorescent product of hydrolysis of fluorogenic phosphatase substrate DiFMUP.
DiFMU is a fluorescent product of hydrolysis of fluorogenic phosphatase substrate DiFMUP. DiFMU excitation wavelength is 358nm and emission can be detected at 455 nm.
6,8-Difluoro-7-hydroxy-4-methylcoumarin Preparation Products And Raw materials
Raw materials
Preparation Products
6,8-Difluoro-7-hydroxy-4-methylcoumarin Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Kewel Chemical Co., Ltd. | 021-64609169 18901607656 | greensnown@163.com | China | 9883 | 50 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 9787 | 55 |
| Shenzhen GeneSeqTools Bioscience & Technology Co. Ltd. | 0755-23251735 13302967066 | sales@geneseqtools.com | China | 1466 | 58 |
| VladaChem GmbH | +49-7246-3082843 +86-18411632868 | info@vladachem.de | Germany | 1854 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Bejing Famous Pharmaceutical Technology Co., Ltd. | 15811073878 | 2559355526@qq.com | China | 10680 | 58 |
| Shanghai Haohong Scientific Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 39718 | 58 |
| Shanghai Beiwanta Biotechnology Co., Ltd. | 021-67187366 19901745723 | info@bwtlab.com | China | 9880 | 58 |
| TargetMol | 400-821-0310 15002144251 | xuexiang.shao@tsbiochem.com | China | 29128 | 58 |





