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2-Propanethiol

CAS No.
75-33-2
Chemical Name:
2-Propanethiol
Synonyms
ISOPROPYL MERCAPTAN;propane-2-thiol;FEMA 3897;2-Mercaptopropane;Isopropanethiol;2-PROPYLMERCAPTAN;IPM(TM);iso-C3H7SH;PROPANTHIOL-2;Isopropylthiol
CBNumber:
CB6466705
Molecular Formula:
C3H8S
Molecular Weight:
76.16
MDL Number:
MFCD00004863
MOL File:
75-33-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-06-23 16:59:16

2-Propanethiol Properties

Melting point −131 °C(lit.)
Boiling point 57-60 °C(lit.)
Density 0.82 g/mL at 25 °C(lit.)
vapor density 2.6 (vs air)
vapor pressure 455 mm Hg ( 37.8 °C)
refractive index n20/D 1.426(lit.)
FEMA 3897 | 2-PROPANETHIOL
FLAVIS Number 12.197 | Propane-2-thiol
Flash point <−30 °F
storage temp. Store below +30°C.
form Liquid
pka pK1:10.86 (25°C,μ=0.1)
color Colorless
Odor Powerful skunk.
Odor Threshold 0.000006ppm
Odor Type alliaceous
biological source synthetic
Water Solubility Slightly soluble in water
Specific Heat Capacity Cp(liquid): 1.91 J/(g·K), at 25℃
Sensitive Air Sensitive
JECFA Number 510
BRN 605260
Henry's Law Constant 1.3×10-3 mol/(m3Pa) at 25℃, Brockbank (2013)
Stability Stable. Highly flammable - note low flashpoint. May form explosive mixtures with air.
InChI 1S/C3H8S/c1-3(2)4/h3-4H,1-2H3
InChIKey KJRCEJOSASVSRA-UHFFFAOYSA-N
SMILES CC(C)S
LogP 1.60
Substances Added to Food (formerly EAFUS) 2-PROPANETHIOL
CAS DataBase Reference 75-33-2(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII E52LR62ETC
NIST Chemistry Reference 2-Propanethiol(75-33-2)
EPA Substance Registry System Isopropyl mercaptan (75-33-2)
UNSPSC Code 12352105
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Exclamation Mark (GHS07)Environment (GHS09)
GHS02,GHS07,GHS09
Signal word  Danger
Hazard statements  H315+H320-H317-H336-H410-H225
Precautionary statements  P501-P261-P273-P272-P240-P210-P233-P243-P241-P242-P271-P264-P280-P370+P378-P391-P337+P313-P305+P351+P338-P362+P364-P303+P361+P353-P333+P313-P304+P340+P312-P403+P233-P403+P235-P405
PPE Eyeshields, Faceshields, Gloves
Hazard Codes  F,Xi
Risk Statements  11-36/37/38-36/38
Safety Statements  16-26-9-37/39-33
RIDADR  UN 2402 3/PG 2
WGK Germany  3
RTECS  TZ7302000
13
TSCA  TSCA listed
HS Code  2930 90 98
HazardClass  3
PackingGroup  II
Storage Class 3 - Flammable liquids
Hazard Classifications Aquatic Acute 1
Aquatic Chronic 1
Flam. Liq. 2
Skin Sens. 1
Hazardous Substances Data 75-33-2(Hazardous Substances Data)
Toxicity LD50 orally in Rabbit: > 2000 mg/kg
REACH Registrations Active
Limited Quantities 1.0 L (0.3 gallon) (liquid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)
NFPA 704
3
2 0

2-Propanethiol price More Price(43)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich W389755 2-Propanethiol natural (US), ≥98%, FG 75-33-2 1 each $191 2026-04-30 Buy
Sigma-Aldrich W389755 2-Propanethiol natural (US), ≥98%, FG 75-33-2 100G $552 2026-04-30 Buy
Sigma-Aldrich W389755 2-Propanethiol natural (US), ≥98%, FG 75-33-2 500G $1370 2026-04-30 Buy
Sigma-Aldrich W389706 2-Propanethiol ≥95% 75-33-2 1 each $55.9 2026-04-30 Buy
Sigma-Aldrich 8.07532 2-Propanethiol for synthesis 75-33-2 100mL $64.5 2026-04-30 Buy
Product number Packaging Price Buy
W389755 1 each $191 Buy
W389755 100G $552 Buy
W389755 500G $1370 Buy
W389706 1 each $55.9 Buy
8.07532 100mL $64.5 Buy

2-Propanethiol Chemical Properties,Uses,Production

Chemical Properties

liquid with an exceedingly unpleasant smell

Occurrence

2-Propanethiol is a volatile sulfur compound that is reported to occur in irradiated beef.

Uses

2-Propanethiol is used in preparation of polyol block copolymer. It is also used as standard for petroleum analysis; as intermediate; as natural gas odorant.

Definition

ChEBI: 2-Propanethiol is an alkanethiol that is propane substituted by a sulfanyl group at position 2.

Preparation

2-Propanethiol is synthesised by the reaction of sodium hydrosulfide and brominated isopropane.

General Description

Isopropyl mercaptan is a white liquid with a strong skunk-like odor. (USCG, 1999)

Air & Water Reactions

Highly flammable. Soluble in water.

Reactivity Profile

2-Propanethiol is incompatible with acids, diazo and azo compounds, halocarbons, isocyanates, aldehydes, alkali metals, nitrides, hydrides, and other strong reducing agents. Reactions with these materials generate heat and in many cases hydrogen gas. May liberate hydrogen sulfide when mixed with an acid.

Hazard

Highly flammable, dangerous fire hazard.

Health Hazard

Inhalation causes loss of sense of smell, muscular weakness, convulsions, respiratory paralysis. Ingestion causes nausea and vomiting. Contact with eyes or skin causes irritation.

Purification Methods

Purify it as for propane-1-thiol above. [Beilstein 1 IV 1498.]

187737-37-7
107-03-9
111-47-7
625-80-9
75-33-2
Synthesis of 2-Propanethiol from propene
Global( 265)Suppliers
Supplier Tel Email Country ProdList Advantage
Jinan Winsor Pharmaceutical Co., Ltd 152-64160071 15318402391 1615850970@qq.com China 449 58
Jinan Yuanze Biotechnology Co., LTD 15063396929; 15063396929 978101703@qq.com China 59 58
Hubei chengfeng chemical co. LTD 13125175253 1005221305@qq.com China 3093 58
Shandong Yinsheng Pharmaceutical Technology Co., Ltd 18865947357 liguiling16888@163.com China 32 58
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TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64

View Lastest Price from 2-Propanethiol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Propanethiol  pictures 2026-05-28 2-Propanethiol
75-33-2
$2.70 10kg 99% 10000kg Hebei Chuanghai Biotechnology Co,.LTD
2-Propanethiol pictures 2026-05-15 2-Propanethiol
75-33-2
$1.10 1g 99.0% Min 100 Tons Shaanxi Didu New Materials Co. Ltd
2-Propanethiol pictures 2026-03-20 2-Propanethiol
75-33-2
$10.00 100KG 99% 100 mt Hebei Chuanghai Biotechnology Co., Ltd
  • 2-Propanethiol pictures
  • 2-Propanethiol
    75-33-2
  • $1.10
  • 99.0% Min
  • Shaanxi Didu New Materials Co. Ltd
2-PROPANETHIOL 2-PROPYLMERCAPTAN iso-C3H7SH Isopropylthiol mercaptanisopropylique Propanethiol-(2) IPM(TM) Propan-2-thiol PROPANTHIOL-2 2-PROPANETHIOL 97+% Isopropyl thioalcohol Thioisopropyl alcohol 2-Propanethiol,98% Isopropy mercaptan 2-Propanethiol, 98% 500ML 2-Propanethiol, 98% 50ML 2-PROPANETHIOL FOR SYNTHESIS 45 KG 2-PROPANETHIOL FOR SYNTHESIS 100 ML 2-PROPANETHIOL FOR SYNTHESIS 500 ML 1-Methylethanethiol 2-propanemercaptan 2-Propanethiol >=97.0% (GC) 2-Propanethiol> 2-Propanethiol,96% 2-Propanethiol USP/EP/BP TIANFU-CHEM - 2-Propanethiol 2-Propanethiol, ≥ 96.0% 2-Propanethiol, Isopropanethiol Phloroglucinol Impurity 130 sopropyl mercaptan 2-Mercaptopropane FEMA 3897 ISOPROPYL MERCAPTAN Isopropanethiol propane-2-thiol 75-33-2 75-33-6 CH32CHSH 75332 Building Blocks Organic Building Blocks Sulfur Compounds Thiols/Mercaptans thiol Flavor