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3-Fluorobenzotrifluoride

3-Fluorobenzotrifluoride structure

CAS No.: 401-80-9

Chemical Name:: 3-Fluorobenzotrifluoride

Synonyms: 1-FLUORO-3-(TRIFLUOROMETHYL)BENZENE;CL052;NSC 10315;3-Fluorobenzotrifluo;3-tetrafluorotoluene;3-Fluorobezotrifluoride;-Fluorobenzotrifluoride;m-fluorotrifluorotoluene;3-Flourobenzo trifluride;M-FLUOROBENZOTRIFLUORIDE

CBNumber:: CB6489111

Molecular Formula:: C7H4F4

Molecular Weight:: 164.1

MDL Number:: MFCD00000382

MOL File:: 401-80-9.mol

MSDS File:: SDS

Last updated:2025-09-25 17:15:13

Product description	Number	Pack Size	Price
3-Fluorobenzotrifluoride 99%	219371	25g	$29.95
3-Fluorobenzotrifluoride >98.0%(GC)	F0390	25g	$54
3-Fluorobenzotrifluoride >98.0%(GC)	F0390	250g	$401
3-Fluorobenzotrifluoride	F588400	50g	$90
3-Fluorobenzotrifluoride	X8282	100g	$54
More product size

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3-Fluorobenzotrifluoride Properties

Melting point	-81.5°C
Boiling point	101-102 °C(lit.)
Density	1.302 g/mL at 25 °C(lit.)
refractive index	n20/D 1.4(lit.)
Flash point	45 °F
storage temp.	Sealed in dry,2-8°C
solubility	Chloroform
form	Oil
color	Clear Colourless
Specific Gravity	1.302
BRN	2045664
InChI	InChI=1S/C7H4F4/c8-6-3-1-2-5(4-6)7(9,10)11/h1-4H
InChIKey	GBOWGKOVMBDPJF-UHFFFAOYSA-N
SMILES	C1(F)=CC=CC(C(F)(F)F)=C1
CAS DataBase Reference	401-80-9(CAS DataBase Reference)
NIST Chemistry Reference	1-Fluoro-3-(trifluoro-methyl)benzene(401-80-9)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02,GHS07

Signal word

Danger

Hazard statements

H225-H315-H319-H335

Precautionary statements

P210-P302+P352-P305+P351+P338

Hazard Codes

F,Xi

Risk Statements

11-36/37/38

Safety Statements

16-26-36-24/25-33-7/9

RIDADR

UN 1993 3/PG 2

WGK Germany

Hazard Note

Flammable/Irritant

HazardClass

PackingGroup

HS Code

29039990

Limited Quantities

1.0 L (0.3 gallon) (liquid)

Excepted Quantities

Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)

NFPA 704

	3
2		0

3-Fluorobenzotrifluoride price More Price(31)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	219371	3-Fluorobenzotrifluoride 99%	401-80-9	25g	$29.95	2025-07-31	Buy
TCI Chemical	F0390	3-Fluorobenzotrifluoride >98.0%(GC)	401-80-9	25g	$54	2025-07-31	Buy
TCI Chemical	F0390	3-Fluorobenzotrifluoride >98.0%(GC)	401-80-9	250g	$401	2025-07-31	Buy
TRC	F588400	3-Fluorobenzotrifluoride	401-80-9	50g	$90	2021-12-16	Buy
AK Scientific	X8282	3-Fluorobenzotrifluoride	401-80-9	100g	$54	2021-12-16	Buy

Product number	Packaging	Price	Buy
219371	25g	$29.95	Buy
F0390	25g	$54	Buy
F0390	250g	$401	Buy
F588400	50g	$90	Buy
X8282	100g	$54	Buy

3-Fluorobenzotrifluoride Chemical Properties,Uses,Production

Chemical Properties

Clear colourless to light yellow liquid

Uses

3-Fluorobenzotrifluoride is a fluorniated toluene used in photochemical reactions with aliphatic amines as well as in photocycloaddition reactions.

Uses

3-Fluorobenzotrifluoride was used:

as fluorinated aromatic solvent to investigate electrogenerated chemiluminescence of 9,10-diphenylanthracene, rubrene and anthracene
used to preparae 2-nitro-5-fluorobenzotrifluoride via nitration reaction

Synthesis

98-16-8

401-80-9

The general procedure for the synthesis of 3-fluorobenzotrifluoride (3-FBT) from m-aminobenzotrifluoride is as follows: in a three-necked round-bottomed flask equipped with a reflux condenser, thermocouples, and a stirring system, m-aminobenzotrifluoride is dissolved in o-dichlorobenzene or benzylnitrile and the reaction temperature is maintained at a temperature lower than 0 °C. Subsequently, 1.4-1.5 molar equivalents of BF3.Et2O or BF3.2H2O were slowly added. tert-butyl nitrite dissolved in the same solvent was added to the reaction mixture at ambient temperature. Next, the reaction medium was heated according to the temperature and time specified in Table (I). The reaction results were recorded in Table (I).

References

[1] Tetrahedron, 1996, vol. 52, # 1, p. 23 - 36
[2] Tetrahedron Letters, 2006, vol. 47, # 32, p. 5705 - 5708
[3] Patent: US2007/276168, 2007, A1. Location in patent: Page/Page column 8
[4] Journal de Chimie Physique et de Physico-Chimie Biologique, 1923, vol. 20, p. 60
[5] Chem. Zentralbl., 1923, vol. 94, # III, p. 918

3-Fluorobenzotrifluoride synthesis

Synthesis of 3-Fluorobenzotrifluoride from 3-Aminobenzotrifluoride

3-Fluorobenzotrifluoride Preparation Products And Raw materials

Raw materials

m-Toluidine Sodium nitrite 1-(Trifluoromethoxy)-3-(trifluoromethyl)benzene TRIFLUOROMETHYLHYPOFLUORITE 4-FLUORO-2-(TRIFLUOROMETHYL)BENZOIC ACID

4-Bromo-3-fluorobenzotrifluoride Benzotrifluoride 3-(trifluoromethyl)diazobenzenetetrafluoroborate 3-(TRIFLUOROMETHYL)PHENYL TRIFLUOROMETHANESULFONATE 2-FLUORO-6-(TRIFLUOROMETHYL)BENZOIC ACID

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Preparation Products

5-Fluoro-2-nitrobenzotrifluoride 3-FLUOROBENZOTRICHLORIDE 4-Fluoroanisole PERFLUORO(METHYLCYCLOHEXANE) 2-FLUORO-4-TRIFLUOROMETHYLPHENYLBORONIC ACID, PINACOL ESTER

Benzoic acid, 4-(methoxymethoxy)-, ethyl ester

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3-Fluorobenzotrifluoride Suppliers

Global( 364)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8757	58
Hebei Yanxi Chemical Co., Ltd.	+8618531123677	faithe@yan-xi.com	China	5853	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5244	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615531151365	mina@chuanghaibio.com	China	18126	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13588	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21603	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Shanxi Naipu Import and Export Co.,Ltd	+86-13734021967 +8613734021967	kaia@neputrading.com	China	1001	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29840	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Yanxi Chemical Co., Ltd.	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
Shanxi Naipu Import and Export Co.,Ltd	58
career henan chemical co	58

View Lastest Price from 3-Fluorobenzotrifluoride manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-01-05	3-Fluorobenzotrifluoride 401-80-9	US $10.00 / KG	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd
2026-01-05	3-Fluorobenzotrifluoride 401-80-9	US $0.00-0.00 / KG	50mg	99%HPLC	2000tons	Shaanxi Dideu Medichem Co. Ltd
2025-12-01	3-Fluorobenzotrifluoride 401-80-9	US $0.00-0.00 / KG	1KG	99.0%	10000KGS	Shaanxi Dideu New Materials Co. Ltd

3-Fluorobenzotrifluoride
401-80-9
US $10.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

3-Fluorobenzotrifluoride
401-80-9
US $0.00-0.00 / KG
99%HPLC
Shaanxi Dideu Medichem Co. Ltd

3-Fluorobenzotrifluoride
401-80-9
US $0.00-0.00 / KG
99.0%
Shaanxi Dideu New Materials Co. Ltd

3-Fluorobenzotrifluoride Spectrum

3-Fluorobenzotrifluoride(401-80-9)MS 3-Fluorobenzotrifluoride(401-80-9)¹HNMR 3-Fluorobenzotrifluoride(401-80-9)¹³CNMR 3-Fluorobenzotrifluoride(401-80-9)IR1 3-Fluorobenzotrifluoride(401-80-9)Raman

401-80-9(3-Fluorobenzotrifluoride)Related Search:

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Tosufloxacin tosylate Benzotrifluoride 3,4-Dichlorobenzotrifluoride m-Xylene Thiophanate-methyl

Benzene Methyl 2-FLUOROBENZOTRIFLUORIDE,O-FLUOROBENZOTRIFLUORIDE 2,4,6-Trinitrotoluene 2-FLUORO-6-(TRIFLUOROMETHYL)BENZOIC ACID

2-FLUORO-4-(TRIFLUOROMETHYL)BENZOIC ACID 5-BROMO-2-FLUOROBENZOTRIFLUORIDE Methyl bromide

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3-Flourobenzo trifluride 3-(Trifluoromethyl)phenyl fluoride 3-Fluoro-1-(trifluoromethyl)benzene benzene,1-fluoro-3-(trifluoromethy 3-Fluorobenzotrifluo Between the fluorine Benzotrifluoride 3-Fluorobezotrifluoride Between three fluorine fluorine toluene m-fluorotrifluorotoluene M-(TrifluoroMethyl)fluorobenzene M-Fluoro(trifluoroMethyl)benzene NSC 10315 1-Fluoro-3-(trifluoromethyl)benzene alpha,alpha,alpha,3-Tetrafluorotoluene M-FLUOROBENZOTRIFLUORIDE 1-FLUORO-3-(TRIFLUOROMETHYL)BENZENE 1-(Trifluoromethyl)-3-fluorobenzene 3-tetrafluorotoluene Benzene, 1-fluoro-3-(trifluoromethyl)- benzene,1-fluoro-3-(trifluoromethyl)- m,alpha,alpha,alpha-Tetrafluorotoluene à,à,à,3-tetrafluorotoluene 3-Fluorobenzotrifluoride 99% 3-(trifluoromethyl)fluorobenzene,1-fluoro-3-(trifluoromethyl)benzene m,a,a,a-Tetrafluorotoluene m,α,α,α-tetrafluorotoluene Toluene, alpha,alpha,alpha-m-tetrafluoro- Toluene, m,alpha,alpha,alpha-tetrafluoro- toluene,m,α,α,α-tetrafluoro- Trifluoromethyl-3-fluorobenzene 3-Fluorotrifluoromethylbenzene 3-Fluorobenzotrifluoride,99% ALPHA,ALPHA,ALPHA,3-TETRAFLUOROTOLUENE 3-FLUOROBENZOTRIFLUORIDE CL052 M-Fluorotrifluoromethyl Benzol 1-(4-methoxyphenyl)-5-tetrazolamine -Fluorobenzotrifluoride 3-Fluorobenzotrifluoride> 3-(Trifluoromethyl)fluorobenzene -Fluorobenzotrifluoride 3- fluorobenzene trifluoro TIANFU-CHEM 3-Fluorobenzotrifluoride 3- fluorotrifluorotoluene 3-Fluorobenezotrifluoride α,α,α,3-tetrafluorotoluene 401-80-9 409-80-9 409-80-9 C7H4F4 FC6H4CF3 Building Blocks C7 Aryl Halogenated Hydrocarbons Organic Building Blocks Aromatic Hydrocarbons (substituted) & Derivatives bc0001