4-Fluoro-2-(trifluoromethyl)benzoic acid
- CAS No.
- 141179-72-8
- Chemical Name:
- 4-Fluoro-2-(trifluoromethyl)benzoic acid
- Synonyms
- TIMTEC-BB SBB006651;RARECHEM AL BO 0635;à,à,à,4-tetrafluoro-o-toluic acid;α,α.α,4-Tetrafluoro-o-toluic Acid;2-trifluoromethyl-4-fluoro-benzoic acid;4-Fluoro-2-(trifluoromethyl)benzoic acid;Benzoicacid, 4-fluoro-2-(trifluoromethyl)-;4-Fluoro-2-(trifluoromethyl)benzoicacid98%;4-Fluoro-2-(trifluoromethyl)benzoicAcid>4-Fluoro-2-(trifluoromethyl)benzoic acid 98%
- CBNumber:
- CB0177221
- Molecular Formula:
- C8H4F4O2
- Molecular Weight:
- 208.11
- MDL Number:
- MFCD00040982
- MOL File:
- 141179-72-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 121-124 °C (lit.) |
|---|---|
| Boiling point | 239.0±40.0 °C(Predicted) |
| Density | 1.4412 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| pka | 3.17±0.36(Predicted) |
| form | Needle-Like Crystalline Powder |
| color | Slightly yellow |
| InChI | InChI=1S/C8H4F4O2/c9-4-1-2-5(7(13)14)6(3-4)8(10,11)12/h1-3H,(H,13,14) |
| InChIKey | JUHPDXOIGLHXTC-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C1=CC=C(F)C=C1C(F)(F)F |
| CAS DataBase Reference | 141179-72-8(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29163990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
4-Fluoro-2-(trifluoromethyl)benzoic acid price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 436135 | 4-Fluoro-2-(trifluoromethyl)benzoic acid 98% | 141179-72-8 | 5g | $39.1 | 2022-05-15 | Buy |
| TCI Chemical | F0577 | 4-Fluoro-2-(trifluoromethyl)benzoic Acid >97.0%(GC)(T) | 141179-72-8 | 1g | $40 | 2026-04-30 | Buy |
| TCI Chemical | F0577 | 4-Fluoro-2-(trifluoromethyl)benzoic Acid >97.0%(GC)(T) | 141179-72-8 | 5g | $137 | 2026-04-30 | Buy |
| Biosynth | FF64212 | 4-Fluoro-2-(trifluoromethyl)benzoic acid | 141179-72-8 | 0.05kg | $150 | 2026-06-04 | Buy |
| Apolloscientific | PC4373D | 4-Fluoro-2-(trifluoromethyl)benzoic acid 98% | 141179-72-8 | 5g | $21 | 2026-06-04 | Buy |
4-Fluoro-2-(trifluoromethyl)benzoic acid Chemical Properties,Uses,Production
Chemical Properties
slightly yellow needle-like crystalline powder
Uses
4-Fluoro-2-(trifluoromethyl)benzoic acid is a substituted benzoic acid derivative. Molecular orbital and empirical methods have been utilized to determine its computed steric and electronic properties.
General Description
4-Fluoro-2-(trifluoromethyl)benzoic acid is a substituted benzoic acid derivative. Molecular orbital and empirical methods have been utilized to determine its computed steric and electronic properties.
Synthesis
Magnesium powder and a small pellet of iodine were added to the reaction flask, which was dried at high temperature, and the reaction system was then nitrogen-protected (air in the reaction system was replaced with nitrogen) through a double-row tube. Anhydrous tetrahydrofuran and 2-bromo-5-fluorobenzotrifluoride were then added to the reaction system under nitrogen atmosphere and the resulting mixture system was heated to reflux in an oil bath and the reaction was stirred at reflux for 2 hours to prepare the corresponding format reagents. The reaction system was cooled to room temperature and then the nitrogen in the reaction system was replaced with the corresponding carbon dioxide and the resulting reaction mixture was stirred and reacted at room temperature overnight. After the reaction, hydrochloric acid was added to the reaction system to acidify the reaction system, the reaction mixture was extracted with ethyl acetate and water, the organic layer was separated and dried, the organic layer was concentrated and the residue was purified by silica gel column chromatography to obtain the target molecule 4-fluoro-2-(trifluoromethyl)benzoic acid.
4-Fluoro-2-(trifluoromethyl)benzoic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Harvest Chemical Industrial Co., Ltd. | 15721252604 17321035817 | sales@harvest-chem.com | China | 2829 | 64 |
| Shijiazhuang Smao Chemical Technology Co., Ltd | 18503219339; 18503219339 | sales@smochem.com | China | 299 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Ark Pharm, Inc. | 847-367-3680 | sales@arkpharminc.com | United States | 1669 | 56 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 |
View Lastest Price from 4-Fluoro-2-(trifluoromethyl)benzoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-11 | 4-fluoro-2-(trifluoromethyl)benzoic acid
141179-72-8
|
$250.00 | 1KG | 98%+ | 300 Tons/ year | Speranza Chemical Co., Ltd. | |
 |
2026-06-30 | 4-Fluoro-2-trifluoroMethylbenzoic acid
141179-72-8
|
1kg | 98% | 1000kg | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2026-03-20 | 4-FLUORO-2-(TRIFLUOROMETHYL)BENZOIC ACID
141179-72-8
|
$10.00 | 1KG | 99% | 100 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-
- 4-fluoro-2-(trifluoromethyl)benzoic acid
141179-72-8
- $250.00
- 98%+
- Speranza Chemical Co., Ltd.
-
- 4-Fluoro-2-trifluoroMethylbenzoic acid
141179-72-8
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- 4-FLUORO-2-(TRIFLUOROMETHYL)BENZOIC ACID
141179-72-8
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
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