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4,7-Dichloroquinoline

4,7-Dichloroquinoline Structure
4,7-Dichloroquinoline structure
CAS No.
86-98-6
Chemical Name:
4,7-Dichloroquinoline
Synonyms
COPPER SEBACATE;Sulfate Impurity;4,7-dichloro-quinolin;Chloroquine Related CoMpound A;tl1473;TL 1473;4, 7-dichloroquine;7-Dichloroquinoline;Chloroquine USP RC A;Amodiaquine Impurity
CBNumber:
CB6490818
Molecular Formula:
C9H5Cl2N
Molecular Weight:
198.05
MDL Number:
MFCD00006774
MOL File:
86-98-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 05:20:07
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4,7-Dichloroquinoline Properties

Melting point 81-83 °C (lit.)
Boiling point 298.4 °F (148°C)
Density 1.4178 (rough estimate)
vapor pressure 0.103Pa at 25℃
refractive index 1.6300 (estimate)
Flash point 164 °C
storage temp. 2-30°C
solubility chloroform: soluble50mg/mL, clear, colorless to greenish-yellow
pka 1.99±0.27(Predicted)
form Powder
color White to pale brown
PH 3.86 (24.9°C)
biological source synthetic
Water Solubility insoluble
BRN 125359
Henry's Law Constant 2.6×101 mol/(m3Pa) at 25℃, Zhang et al. (2010)
InChI 1S/C9H5Cl2N/c10-6-1-2-7-8(11)3-4-12-9(7)5-6/h1-5H
InChIKey HXEWMTXDBOQQKO-UHFFFAOYSA-N
SMILES Clc1ccc2c(Cl)ccnc2c1
LogP 3.193 at 25℃
CAS DataBase Reference 86-98-6(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII Z61O2HEQ2J
NIST Chemistry Reference Quinoline, 4,7-dichloro-(86-98-6)
EPA Substance Registry System 4,7-Dichloroquinoline (86-98-6)
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Environment (GHS09)
GHS07,GHS09
Signal word  Warning
Hazard statements  H315-H317-H319-H411
Precautionary statements  P261-P264-P273-P280-P302+P352-P305+P351+P338
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-22
WGK Germany  3
RTECS  VB4200000
Hazard Note  Irritant
TSCA  TSCA listed
HS Code  29334910
Storage Class 13 - Non Combustible Solids
Hazard Classifications Aquatic Chronic 2
Eye Irrit. 2
Skin Irrit. 2
Skin Sens. 1
REACH Registrations Active
NFPA 704
1
2 0

4,7-Dichloroquinoline price More Price(86)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR2438 Chloroquine Related Compound A Pharmaceutical Secondary Standard; Certified Reference Material 86-98-6 50MG $742 2026-04-30 Buy
Sigma-Aldrich 141437 4,7-Dichloroquinoline ≥99% 86-98-6 25g $129 2026-04-30 Buy
Sigma-Aldrich 1118328 Chloroquine Related Compound A United States Pharmacopeia (USP) Reference Standard 86-98-6 15MG $1290 2026-04-30 Buy
Sigma-Aldrich 1118328 Chloroquine Related Compound A United States Pharmacopeia (USP) Reference Standard 86-98-6 25mg $1220 2022-05-15 Buy
TCI Chemical D1100 4,7-Dichloroquinoline >98.0%(GC) 86-98-6 25g $44 2026-04-30 Buy
Product number Packaging Price Buy
PHR2438 50MG $742 Buy
141437 25g $129 Buy
1118328 15MG $1290 Buy
1118328 25mg $1220 Buy
D1100 25g $44 Buy

4,7-Dichloroquinoline Chemical Properties, Uses, Production

Chemical Properties

white to light yellow crystal powder

Uses

4,7-Dichloroquinoline is used in the synthesis of hybrid aminoquinoline-triazine derivatives that show anti-microbial activity. In addition, it is used in the synthesis of novel oxazolidinones as anti -microbial agents showing efficacy against common bacterial strains. Chloroquinoline impurity.

Uses

4,7-Dichloroquinoline is used as a drug chloroquine phosphate intermediate. It was used in the synthesis of piperaquine. and as starting reagent in the synthesis of {3-amino-5-[(7-chloro-4-quinolyl)amino]phenyl}methanol.

General Description

Chloroquine Related Compound A is an impurity of chloroquine, which is a 9-aminoquinoline drug that effectively inhibits viral infections in humans.

Flammability and Explosibility

Not classified

Synthesis

4,7-Dichloroquinoline is obtained by chlorination of 7-chloro-4-hydroxyquinoline.

Purification Methods

Crystallise the dichloroquinoline from MeOH or 95% EtOH. [Beilstein 20/7 V 316.]

4,7-Dichloroquinoline synthesis

86-99-7
86-98-6
Synthesis of 4,7-Dichloroquinoline from 7-Chloroquinolin-4-ol

4,7-Dichloroquinoline Preparation Products And Raw materials

Raw materials

7-Chloroquinolin-4-ol

Preparation Products

7-Chloro-4-piperazinoquinoline 4-Bromo-7-chloroquinoline Hydroxychloroquine Chloroquine 7-chloroquinoline-4-carboxylic acid
4-Methoxyquinoline Desethyl hydroxy chloroquine N-(7-Chloro-4-quinolinyl)-N'-[2-[(7-chloro-4-quinolinyl)aMino]ethyl]-1,2-ethanediaMine Quinoline, 3,4,7-trichloro- 4-Chloro-5,6,7,8-tetrahydroquinoline
4,7,8-Trichloroquinoline Amodiaquine

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4,7-Dichloroquinoline Suppliers

Global Suppliers ( 562)
Supplier Tel Email Country ProdList Advantage
Jinan Wald Chemical Co., Ltd. 0531-88773586 13210588999 304264064@qq.com China 192 58
Changzhou Xinda Biotechnology Co., Ltd 0519-85519868 18915088878 xiaoweng106108@163.com China 99 58
Zhengzhou Hong Sheng Pharmaceutical Technology Co. Ltd. 0371-55695890 15637198702 1677336983@qq.com China 13178 58
Zhengzhou HongSheng Pharmaceutical Co., Ltd. 0371-0371-13526885213 15637198702 hsyykjchem@163.com China 1854 58
Shanghai jing Hao pharmaceutical technology co., LTD 021-68900963 15618693615 sales@jinghaopharma.com China 300 58
Suzhou Highfine Biotech Co., Ltd 0512-69209928 18796809688 zhouyingxiang@highfine.com China 1846 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TAIYUAN RHF CO.,LTD. +86 351 7031519 sales@RHFChem.com China 2334 56
Supplier Advantage
Jinan Wald Chemical Co., Ltd. 58
Changzhou Xinda Biotechnology Co., Ltd 58
Zhengzhou Hong Sheng Pharmaceutical Technology Co. Ltd. 58
Zhengzhou HongSheng Pharmaceutical Co., Ltd. 58
Shanghai jing Hao pharmaceutical technology co., LTD 58
Suzhou Highfine Biotech Co., Ltd 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Alfa Aesar 84
TAIYUAN RHF CO.,LTD. 56

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View Latest Price from 4,7-Dichloroquinoline manufacturers

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4,7-Dichloroquinoline pictures 2026-09-15 4,7-Dichloroquinoline
86-98-6
 0.99 RongNa Biotechnology Co.,Ltd
4,7-Dichloroquinoline pictures 2026-09-15 4,7-Dichloroquinoline
86-98-6
 1kg 99% GC 500kgs WUHAN FORTUNA CHEMICAL CO., LTD
4,7-Dichloroquinoline pictures 2026-09-15 4,7-Dichloroquinoline
86-98-6
 1g 99% 20mt Jinan Finer Chemical Co., Ltd

4,7-Dichloroquinoline Spectrum

4,7-Dichloroquinoline(86-98-6)MS4,7-Dichloroquinoline(86-98-6)1HNMR4,7-Dichloroquinoline(86-98-6)13CNMR4,7-Dichloroquinoline(86-98-6)IR14,7-Dichloroquinoline(86-98-6)IR24,7-Dichloroquinoline(86-98-6)Raman

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Hydroxychloroquine Sulfate Impurity 7（Hydroxychloroquine Sulfate EP Impurity G） Hydroxychloroquine Sulfate EP Impurity G Sulfate Impurity 4,7-DICHLOROQUINOLINE 4,7-dichloro-quinolin TL 1473 tl1473 Amobiquine Impurity 1 4,7-Dichloroquinoline,97% 4,7-DICHLOLROQUINOLINE 4,7-DICHLOROQUINOLINE CHLOROQUINE PHOSPHATE 7-Dichloroquinoline Chloroquine Related Compound A (25 mg) (4,7-dichloroquinoline) 4,7-Dichloroquinoline,98% 4,7-Dichloroquinoline,95%,tech. Quinoline, 4,7-dichloro- 4,7-Dichloro-1-azanaphthalene 4,7-DICHLOROQUINOLINE, 99+% 4,7-Dichloroquinoline(For Quinoline) Hydroxychloroquine sulfate Impurity 4 Amodiaquine Impurity 1 (Hydroxychloroquine Sulfate EP Impurity G) 4,7-Dichloroquinoline> Chloroquine USP RC A N4-(7-chloroquinolin-4-yl)-N1-ethylpentane-1,4-diamine sulfate Amodiaquine Dichloro Impurity (Hydroxychloroquine EP Impurity G/ Chloroquine?Related Compound A) 4,7-DICHLOROQUINOLINE 86-98-6 Chloroquine?Related Compound A (Amodiaquine Dichloro Impurity/ Hydroxychloroquine EP Impurity G) Hydroxychloroquine EP Impurity G (Amodiaquine Dichloro Impurity) High quailty 4,7-Dichloroquinoline 86-98-6 4,7- DichloroquinolineQ: What is 4,7- Dichloroquinoline Q: What is the CAS Number of 4,7- Dichloroquinoline Q: What is the storage condition of 4,7- Dichloroquinoline Chloroquine Related Compound A (4,7-dichloroquinoline) (1118328) 4, 7-dichloroquine Hydroxychloroquine Sulfate Impurity G Chloroquine USP Related Compound A 4,7-dichloroquinoline (4,7-DCQ) 4,7-Dichloroquinolone 2,2'-((4-((7-chloroquinolin-4-yl)amino)pentyl)azanediyl)diethanol Hydroxychloroquine EP Impurity G 4,7-Dichlrorquinoline Amodiaquine Impurity Hydroxychloroquine Sulfate EP Impurity G (Chloroquine USP Related Compound A) 4-((7-chloroquinolin-4-yl)amino)-2-((diethylamino)methyl)-6-nitropheno Chloroquine phosphate impurity C CRS Chloroquine Related CoMpound A COPPER SEBACATE 86-98-6 7640-85-7 C9H5Cl2N Halogenated Heterocycles Heterocyclic Building Blocks Haloquinolines Quinolines Building Blocks Building Blocks C8 to C10 Chemical Synthesis Halogenated Heterocycles Heterocyclic Building Blocks Haloquinolines