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6-Chloro-benzofuran-3-one

6-Chloro-benzofuran-3-one Structure
6-Chloro-benzofuran-3-one structure
CAS No.
3260-78-4
Chemical Name:
6-Chloro-benzofuran-3-one
Synonyms
6-Chlorobenzofuran-3(2H)-one;6-BROMOBENZOFURAN-3(2H)-ONE;6-Bromo-3-Benzofuranone;6-Chloro-benzofuran-3-one;6-chloro-1-benzofuran-3-one;6-Chloro-3(2H)-benzofuranone;3(2H)-BENZOFURANONE, 5-BROMO-;6-CHLORO-2H-1-BENZOFURAN-3-ONE;3(2H)-Benzofuranone, 6-chloro-;6-chloro-2,3-dihydro-1-benzofuran-3-one
CBNumber:
CB6495510
Molecular Formula:
C8H5ClO2
Molecular Weight:
168.58
MDL Number:
MFCD06738725
MOL File:
3260-78-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:54:17
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6-Chloro-benzofuran-3-one Properties

Melting point 123-123.5 °C
Boiling point 304.3±42.0 °C(Predicted)
Density 1.428±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
Appearance Yellow to brown Solid
InChI InChI=1S/C8H5ClO2/c9-5-1-2-6-7(10)4-11-8(6)3-5/h1-3H,4H2
InChIKey QSYZLDHZMYWEKL-UHFFFAOYSA-N
SMILES O1C2=CC(Cl)=CC=C2C(=O)C1

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H312-H332
Precautionary statements  P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P330-P363-P501
HS Code  2932990090

6-Chloro-benzofuran-3-one price More Price(51)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 265771 5-Bromo-Benzofuran-3-One Asreported 3260-78-4 250mg $368 2026-06-03 Buy
Usbiological 265771 5-Bromo-Benzofuran-3-One Asreported 3260-78-4 500mg $509 2026-06-03 Buy
Usbiological 265771 5-Bromo-Benzofuran-3-One Asreported 3260-78-4 1g $781 2026-06-03 Buy
Usbiological 265771 5-Bromo-Benzofuran-3-One Asreported 3260-78-4 2g $1087 2026-06-03 Buy
Usbiological 265771 5-Bromo-Benzofuran-3-One Asreported 3260-78-4 5g $1534 2026-06-03 Buy
Product number Packaging Price Buy
265771 250mg $368 Buy
265771 500mg $509 Buy
265771 1g $781 Buy
265771 2g $1087 Buy
265771 5g $1534 Buy

6-Chloro-benzofuran-3-one Chemical Properties, Uses, Production

Chemical Properties

Orange Solid

Uses

6-Bromobenzofuran-3(2H)-one is a useful reactant for the preparation of tricyclic sulfones as RORγ modulators.

Synthesis

Benzoicacid,2-(carboxymethoxy)-4-chloro-

401622-26-2

6-CHLORO-BENZOFURAN-3-ONE

3260-78-4

Step 3: 2-(carboxymethoxy)-4-chlorobenzoic acid (11.5 g, 50 mmol) obtained from step 2 was dissolved in acetic anhydride (100 ml) and anhydrous sodium acetate (10.0 g, excess) was added. The reaction mixture was heated to 150 °C and maintained for 4 hours. During the reaction, the color of the mixture changed to deep red. Upon completion of the reaction, the mixture was cooled to room temperature and quenched carefully with ice-cold water. The resulting red solid was collected by filtration and washed well with water. The washed red solid was suspended in 1N HCl and refluxed for 2 hours. After the reaction, 6-chlorobenzofuran-3(2H)-one precipitated from the mixture as a deep red solid. The product was isolated by filtration, washed well with water and dried at 40 °C and used in subsequent steps without further purification. Yield: 5.8 g (69%); MS data: (M + H): 169.

References

[1] Patent: US2009/54454, 2009, A1. Location in patent: Page/Page column 22
[2] Patent: WO2004/99191, 2004, A2. Location in patent: Page 49
[3] Patent: US2005/4162, 2005, A1. Location in patent: Page/Page column 12

6-Chloro-benzofuran-3-one Preparation Products And Raw materials

Raw materials

Benzoicacid,2-(carboxymethoxy)-4-chloro- 3-Benzofuranol, 6-chloro-, acetate

Preparation Products

2-(6-Chlorobenzofuran-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

6-Chloro-benzofuran-3-one Suppliers

Global Suppliers ( 124)
Supplier Tel Email Country ProdList Advantage
Tianjing Geneston Bio-tech Co.,Ltd. 022-60131465 18920720807 zishan_1986@163.com China 744 58
Chembest Research Laboratories Limited 021-20908456 sales@BioChemBest.com China 5996 61
ForeChem (Nantong) Technology Co.,Ltd. 513-85982855 18921614129 sales@xianxingpharm.com China 2712 61
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078 sales@jingyan-chemical.com China 9963 60
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
XiaoGan ShenYuan ChemPharm co,ltd 15527621225; 15527621225 1791901229@qq.com China 6741 52
Wuhan TCASChem Technology Co., Ltd. 027-86697669 13986148687 sales@tcaschem.com China 4000 55
Shanghai Topbiochem Technology Co., Ltd +86-21-60341587 sales@topbiochem.com China 6166 58
Supplier Advantage
Tianjing Geneston Bio-tech Co.,Ltd. 58
Chembest Research Laboratories Limited 61
ForeChem (Nantong) Technology Co.,Ltd. 61
Capot Chemical Co., Ltd 66
JinYan Chemicals(ShangHai) Co.,Ltd. 60
Accela ChemBio Co.,Ltd. 64
Chemsky（shanghai）International Co.,Ltd. 50
XiaoGan ShenYuan ChemPharm co,ltd 52
Wuhan TCASChem Technology Co., Ltd. 55
Shanghai Topbiochem Technology Co., Ltd 58

View Latest Price from 6-Chloro-benzofuran-3-one manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
6-CHLORO-BENZOFURAN-3-ONE pictures 2024-07-11 6-CHLORO-BENZOFURAN-3-ONE
3260-78-4
 $1.00 1KG 98% 20T Shaanxi Dideu Medichem Co. Ltd
5-Bromobenzofuran-3-one pictures 2022-01-04 5-Bromobenzofuran-3-one
3260-78-4
 1g 98%minHPLC 50kgs/month Shanghai Rlavie Technology Co ltd

6-Chloro-benzofuran-3-one Spectrum

6-CHLORO-BENZOFURAN-3-ONE(3260-78-4)1HNMR

3260-78-4 (6-Chloro-benzofuran-3-one) Related Search:

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5-Bromo-3(2H)-benzofuranone

1of3

3(2H)-BENZOFURANONE, 5-BROMO- 6-Chloro-3(2H)-benzofuranone 6-Bromo-3-Benzofuranone 3(2H)-Benzofuranone, 6-chloro- 6-chloro-2,3-dihydro-1-benzofuran-3-one 6-chloro-1-benzofuran-3-one 6-CHLORO-2H-1-BENZOFURAN-3-ONE 6-chloro-2,3-dihydro-1-benzofuran-3-one - [C86492] 6-BROMOBENZOFURAN-3(2H)-ONE 6-Chlorobenzofuran-3(2H)-one 6-Chloro-benzofuran-3-one 3260-78-4 3620-78-4