Danshensu Sodium Salt
- CAS No.
- 81075-52-7
- Chemical Name:
- Danshensu Sodium Salt
- Synonyms
- DS 182;Salianic acid A;Sodium Dahshensu;(R)-Sodium Danshensu;Danshensu Sodium Salt;13C6]-Danshensu sodium salt;(R)-(+)-3-(3,4-Dihydroxyphenyl)lactic acid;3-(3′,4′-Dihydroxyphenyl)-(2R)-lactic acid sodium salt;(R)-α,3,4-Trihydroxy-benzenepropanoic acid sodium salt
- CBNumber:
- CB6547396
- Molecular Formula:
- C9H11NaO5
- Molecular Weight:
- 222.17
- MDL Number:
- MFCD07781415
- MOL File:
- 81075-52-7.mol
- MSDS File:
- SDS
| Melting point | >230°C (dec.) |
|---|---|
| storage temp. | 2-8°C |
| solubility | H2O: soluble20mg/mL, clear |
| form | powder |
| color | white to beige |
| optical activity | [α]/D +30 to +40°, c = 1 in H2O |
| Water Solubility | H2O: 20mg/mL, clear |
| Stability | Hygroscopic |
| InChI | 1S/C9H10O5.Na/c10-6-2-1-5(3-7(6)11)4-8(12)9(13)14;/h1-3,8,10-12H,4H2,(H,13,14);/q;+1/p-1/t8-;/m1./s1 |
| InChIKey | ZMMKVDBZTXUHFO-DDWIOCJRSA-M |
| SMILES | OC1=C(O)C=CC(C[C@@H](O)C([O-])=O)=C1.[Na+] |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
Danshensu Sodium Salt price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML0679 | Danshensu sodium salt ≥98% (HPLC) | 81075-52-7 | 5mg | $98.5 | 2026-04-30 | Buy |
| Sigma-Aldrich | SML0679 | Danshensu sodium salt ≥98% (HPLC) | 81075-52-7 | 25mg | $397 | 2026-04-30 | Buy |
| TRC | TRC-S621905-5MG | (R)-Sodium Danshensu | 81075-52-7 | 5mg | $91 | 2026-06-03 | Buy |
| TRC | TRC-S621905-1MG | (R)-Sodium Danshensu | 81075-52-7 | 1mg | $59 | 2026-06-03 | Buy |
| TRC | TRC-S621905-10MG | (R)-Sodium Danshensu | 81075-52-7 | 10mg | $147 | 2026-06-03 | Buy |
Danshensu Sodium Salt Chemical Properties,Uses,Production
Uses
Sodium Danshensu is exhibits protective effects on the excitotoxicity of monosodium glutamate in the late stage of pregnancy on developing mouse fetal brain.
Biochem/physiol Actions
Danshensu is an active component of Salvia miltiorrhiza (Danshen) that suppresses the formation of reactive oxygen species, inhibits platelet adhesion and aggregation, and protects myocardium against ischemia. Danshensu is cardioprotective, which protects myocardium from the reperfusion injury and inhibits apoptosis of H9c2 cardiomyocytes via Akt and ERK1/2 phosphorylation.
in vivo
Danshensu (Dan shen suan A; 25, 50, 100mg/kg; oral administration daily for 7 continuous days or i.v. once) sodium before SARS-CoV-2 S infection dose-dependently alleviates the pathological alterations in mice infected with SARS-CoV-2 S[1].
| Animal Model: | Adult BALB/c mice (male, 6-8 weeks, 20±2g)[1] |
| Dosage: | 25, 50, 100mg/kg |
| Administration: | Oral administration (daily for 7 continuous days) or i.v. (once) |
| Result: | Could prevent SARS-CoV-2 S protein-induced acute lung inflammation. Ameliorated inflammatory cytokines in serum and lung tissue. |
Danshensu Sodium Salt Preparation Products And Raw materials
Raw materials
Preparation Products
Danshensu Sodium Salt Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Target molecule Corp. | 857-239-0968 | service1@targetmol.com | United States | 2548 | 60 |
| PCL - Business, Laboratory Pharmaceutical | 19150123681 | Hu.xinyue@purechemland.com | China | 3562 | 58 |
| Shanghai Beiwanta Biotechnology Co., Ltd. | 021-67187366 19901745723 | info@bwtlab.com | China | 9884 | 58 |
| SHAANXI?DIDEU?MEDICHEM CO.LTD | 17691182729 17392216275 | 1073@dideu.com | China | 9993 | 58 |
| TargetMol | 400-821-0310 15002144251 | xuexiang.shao@tsbiochem.com | China | 29128 | 58 |
| LGC Science (Shanghai) Ltd. | 17717235263 17717235263 | offer.de@lgcgroup.com | China | 38135 | 58 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |
| Target molecule Corp. | 60 |
| PCL - Business, Laboratory Pharmaceutical | 58 |
| Shanghai Beiwanta Biotechnology Co., Ltd. | 58 |
| SHAANXI?DIDEU?MEDICHEM CO.LTD | 58 |
| TargetMol | 58 |
| LGC Science (Shanghai) Ltd. | 58 |
