GPX4 antibody
- CAS No.
- Chemical Name:
- GPX4 antibody
- Synonyms
- GPX4 antibody;Rabbit Monoclonal GPX4 Antibody
- CBNumber:
- CB65632433
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
GPX4 antibody price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biorbyt Ltd | orb622480 | GPX4 Antibody | 50μl | $400 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb622480 | GPX4 Antibody | 100μl | $540 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb192419 | GPX4 Antibody | 50μl | $350 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb192419 | GPX4 Antibody | 100μl | $480 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb5346 | GPX4 antibody | 100μg | $421.6 | 2021-12-16 | Buy |
GPX4 antibody Chemical Properties,Uses,Production
Source
Rabbit
Reactivity
Human;Mouse;Monkey
Background
The selenoprotein glutathione peroxidase 4 is a master regulator of ferroptosis, a form of programmed cell death induced by iron-dependent lipid peroxidation. GPX4 converts lipid hydroperoxides to non-toxic lipid alcohols, therefore preventing ferroptosis. Research studies show that selenium enhances GPX4 expression and inhibits ferroptotic death to protect neurons. In addition, some therapy-resistant cancer cells depend on GPX4 to survive. Loss of GPX4 leads to ferroptosis and thus prevents tumor relapse in mice. Furthermore, redox homeostasis mediated by GPX4 is essential for activation of the cytosolic DNA-sensing cGAS-STING pathway and initiation of the subsequent innate immune response.
References
[1] Wenzel, S.E. et al. (2017) Cell 171, 628-641.e26.
[2] Bersuker, K. et al. (2019) Nature 575, 688-92.
[3] Alim, I. et al. (2019) Cell 177, 1262-1279.e25.
[4] Hangauer, M.J. et al. (2017) Nature 551, 247-50.
[5] Jia, M. et al. (2020) Nat Immunol 21, 727-35.
GPX4 antibody Preparation Products And Raw materials
Raw materials
Preparation Products
GPX4 antibody Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Universal Biotech Co.,Ltd | 15921930842 15921930842 | yh-wang@univ-bio.com | China | 25030 | 58 |
| Hubei ipodix Biotech Technology Co., Ltd | 18007124176 | ipdshengwu@163.com | China | 4801 | 58 |
| MCE(MedChemExpress) | 400-199-8808 18019480960 | sales@medchemexpress.cn | China | 23919 | 58 |
| Supplier | Advantage |
|---|---|
| Shanghai Universal Biotech Co.,Ltd | 58 |
| Hubei ipodix Biotech Technology Co., Ltd | 58 |
| MCE(MedChemExpress) | 58 |
