Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>3-chloro-5-((6-oxo-1-((6-oxo-5-(trifluoromethyl)-1,6-dihydropyridazin-3-yl) methyl)-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile

3-chloro-5-((6-oxo-1-((6-oxo-5-(trifluoromethyl)-1,6-dihydropyridazin-3-yl) methyl)-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile

3-chloro-5-((6-oxo-1-((6-oxo-5-(trifluoromethyl)-1,6-dihydropyridazin-3-yl) methyl)-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile Structure
3-chloro-5-((6-oxo-1-((6-oxo-5-(trifluoromethyl)-1,6-dihydropyridazin-3-yl) methyl)-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile structure
CAS No.
1591823-76-5
Chemical Name:
3-chloro-5-((6-oxo-1-((6-oxo-5-(trifluoromethyl)-1,6-dihydropyridazin-3-yl) methyl)-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile
Synonyms
Ulonivirine;MK-8507;Ulonivirine/MK-8507;Ulonivirine (Synonyms: MK-8507);3-chloro-5-((6-oxo-1-((6-oxo-5-(trifluoromethyl)-1,6-dihydropyridazin-3-yl) methyl)-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile;Benzonitrile, 3-chloro-5-[[1-[[1,6-dihydro-6-oxo-5-(trifluoromethyl)-3-pyridazinyl]methyl]-1,6-dihydro-6-oxo-4-(trifluoromethyl)-5-pyrimidinyl]oxy]-;3-Chloro-5-((6-oxo-1-((6-oxo-5-(trifluoromethyl)-1,6-dihydropyridazin-3-yl)methyl)-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile , Ulonivirine
CBNumber:
CB65822377
Molecular Formula:
C18H8ClF6N5O3
Molecular Weight:
491.73
MDL Number:
MOL File:
1591823-76-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41
Request For Quotation

3-chloro-5-((6-oxo-1-((6-oxo-5-(trifluoromethyl)-1,6-dihydropyridazin-3-yl) methyl)-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile Properties

Density 1.65±0.1 g/cm3(Predicted)
form Solid
pka 9.65±0.60(Predicted)
color White to light yellow
FDA UNII 4NS011EGKZ

3-chloro-5-((6-oxo-1-((6-oxo-5-(trifluoromethyl)-1,6-dihydropyridazin-3-yl) methyl)-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0564146 Ulonivirine 98.61% 1591823-76-5 5mg $184 2026-06-04 Buy
ChemScene CS-0564146 Ulonivirine 98.61% 1591823-76-5 10mg $276 2026-06-04 Buy
ChemScene CS-0564146 Ulonivirine 98.61% 1591823-76-5 25mg $471 2026-06-04 Buy
ChemScene CS-0564146 Ulonivirine 98.61% 1591823-76-5 50mg $682 2026-06-04 Buy
ChemScene CS-0564146 Ulonivirine 98.61% 1591823-76-5 100mg $991 2026-06-04 Buy
Product number Packaging Price Buy
CS-0564146 5mg $184 Buy
CS-0564146 10mg $276 Buy
CS-0564146 25mg $471 Buy
CS-0564146 50mg $682 Buy
CS-0564146 100mg $991 Buy

3-chloro-5-((6-oxo-1-((6-oxo-5-(trifluoromethyl)-1,6-dihydropyridazin-3-yl) methyl)-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile Chemical Properties, Uses, Production

Uses

Ulonivirine (MK-8507) is an orally active non-nucleoside reverse transcriptase inhibitor with high antiviral activity. Ulonivirine can be used for the research of HIV-1 infection[1][2][3][4].

IC 50

HIV-1

References

[1] Schürmann D, et al. Single Oral Doses of MK-8507, a Novel Non-Nucleoside Reverse Transcriptase Inhibitor, Suppress HIV-1 RNA for a Week. J Acquir Immune Defic Syndr. 2022 Feb 1;89(2):191-198. DOI:10.1097/QAI.0000000000002834
[2] Gillespie SW, et al. Islatravir: evaluation of clinical development for HIV and HBV. Expert Opin Investig Drugs. 2024 Feb;33(2):85-93. DOI:10.1080/13543784.2024.2305130
[3] Ankrom W, et al. Pharmacokinetic and Safety Profile of the Novel HIV Nonnucleoside Reverse Transcriptase Inhibitor MK-8507 in Adults without HIV. Antimicrob Agents Chemother. 2021 Nov 17;65(12):e0093521. DOI:10.1128/AAC.00935-21
[4] Gillespie G, et al. Fluoride Pharmacokinetics in Urine and Plasma Following Multiple Doses of MK-8507, an Investigational, Oral, Once-Weekly Nonnucleoside Reverse Transcriptase Inhibitor. J Clin Pharmacol. 2022 Feb;62(2):199-205. DOI:10.1002/jcph.1957

3-chloro-5-((6-oxo-1-((6-oxo-5-(trifluoromethyl)-1,6-dihydropyridazin-3-yl) methyl)-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

3-chloro-5-((6-oxo-1-((6-oxo-5-(trifluoromethyl)-1,6-dihydropyridazin-3-yl) methyl)-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile Suppliers

Global Suppliers ( 19)
Supplier Tel Email Country ProdList Advantage
Chengdu Novel Biomedical Co., Ltd. 028-85255396 18302801538 cdnovell@163.com China 2445 58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd 15317229551 15151849396@163.com China 964 58
Chunchuang (Wuhan) Technology Co., Ltd 15727060112 yutianchun2007@126.com China 9867 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 59929 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Wuhan Jingkangen Biomedical Technology Co., Ltd 13720134139 086-15871494362 13720134139 orders@jknbiochem.com China 7283 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 sales@chemhifuture.com China 5985 58
Olix ( Hubei) Pharmaceutical Technology Co., Ltd 17316404525 17316404525 209533805@qq.com China 9769 58
Changzhou Yourui Pharmaceutical Technology Co., Ltd 18168818882 877458914@qq.com China 8663 58
Chengdu Peter-like Biotechnology Co., Ltd. 028-81700200 13308200041 2851167782@qq.com China 10763 58
Supplier Advantage
Chengdu Novel Biomedical Co., Ltd. 58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd 58
Chunchuang (Wuhan) Technology Co., Ltd 58
Bide Pharmatech Ltd. 58
TargetMol Chemicals Inc. 58
Wuhan Jingkangen Biomedical Technology Co., Ltd 58
Nantong QuanYi Biotechnology Co., Ltd 58
Olix ( Hubei) Pharmaceutical Technology Co., Ltd 58
Changzhou Yourui Pharmaceutical Technology Co., Ltd 58
Chengdu Peter-like Biotechnology Co., Ltd. 58

View Latest Price from 3-chloro-5-((6-oxo-1-((6-oxo-5-(trifluoromethyl)-1,6-dihydropyridazin-3-yl) methyl)-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ulonivirine pictures 2026-07-27 Ulonivirine
1591823-76-5
 $1520.00-2500.00 10g TargetMol Chemicals Inc.
  • Ulonivirine pictures
  • Ulonivirine
    1591823-76-5
  • $1520.00-2500.00
  • TargetMol Chemicals Inc.

1591823-76-5 (3-chloro-5-((6-oxo-1-((6-oxo-5-(trifluoromethyl)-1,6-dihydropyridazin-3-yl) methyl)-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile) Related Search:

3-chloro-5-((6-oxo-1-((6-oxo-5-(trifluoromethyl)-1,6-dihydropyridazin-3-yl) methyl)-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile Ritonavir Ivermectin PLERIXAFOR Gag-Pol polyprotein, HIV (440a.a, His)
P24 protein, HIV-1 (BAH97658, HIS)

1of2

3-chloro-5-((6-oxo-1-((6-oxo-5-(trifluoromethyl)-1,6-dihydropyridazin-3-yl) methyl)-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile Benzonitrile, 3-chloro-5-[[1-[[1,6-dihydro-6-oxo-5-(trifluoromethyl)-3-pyridazinyl]methyl]-1,6-dihydro-6-oxo-4-(trifluoromethyl)-5-pyrimidinyl]oxy]- Ulonivirine (Synonyms: MK-8507) Ulonivirine/MK-8507 MK-8507 3-Chloro-5-((6-oxo-1-((6-oxo-5-(trifluoromethyl)-1,6-dihydropyridazin-3-yl)methyl)-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile , Ulonivirine Ulonivirine 1591823-76-5 C18H8ClF6N5O3