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SRI 37892

SRI 37892 Structure
SRI 37892 structure
CAS No.
1030769-75-5
Chemical Name:
SRI 37892
Synonyms
SRI 37892;SRI 37892, 10 mM in DMSO;Benzamide, 4-(1H-benzimidazol-1-yl)-N-[4-(1,2,3,4-tetrahydro-2-oxo-6-quinolinyl)-2-thiazolyl]-;4-(1H-Benzo[d]imidazol-1-yl)-N-(4-(2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)thiazol-2-yl)benzamide
CBNumber:
CB65867268
Molecular Formula:
C26H19N5O2S
Molecular Weight:
465.53
MDL Number:
MOL File:
1030769-75-5.mol
MSDS File:
SDS
Last updated:2025-04-18 09:52:31
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SRI 37892 Properties

Density 1.46±0.1 g/cm3(Predicted)
pka 6.67±0.50(Predicted)
form Solid
color Light yellow to brown

SRI 37892 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth FRB76975 4-(1H-Benzo[D]imidazol-1-yl)-N-(4-(2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)thiazol-2-yl)benzamide 1030769-75-5 25mg $1019 2026-06-04 Buy
Biosynth FRB76975 4-(1H-Benzo[D]imidazol-1-yl)-N-(4-(2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)thiazol-2-yl)benzamide 1030769-75-5 50mg $1417 2026-06-04 Buy
ChemScene CS-0063430 SRI 37892 99.28% 1030769-75-5 1mg $455 2026-06-04 Buy
ChemScene CS-0063430 SRI 37892 99.28% 1030769-75-5 5mg $1137 2026-06-04 Buy
aablocks AA01X70B SRI 37892 98 1030769-75-5 1mg $298 2026-06-01 Buy
Product number Packaging Price Buy
FRB76975 25mg $1019 Buy
FRB76975 50mg $1417 Buy
CS-0063430 1mg $455 Buy
CS-0063430 5mg $1137 Buy
AA01X70B 1mg $298 Buy

SRI 37892 Chemical Properties, Uses, Production

Uses

SRI 37892 is a small molecule compound inhibitor of Frizzled protein 7 (Fzd7) with inhibitory activity against cancer cell proliferation (IC50=2μM). SRI 37892 significantly blocks Wnt/Fzd7 signaling. SRI 3789 can be used in the research of developing cancer therapeutic agents [1].

References

[1] Zhang W, et al. Discovery of novel frizzled-7 inhibitors by targeting the receptor's transmembrane domain. Oncotarget. 2017 Sep 6;8(53):91459-91470. DOI:10.18632/oncotarget.20665

SRI 37892 Preparation Products And Raw materials

Raw materials

Preparation Products

SRI 37892 Suppliers

Global Suppliers ( 11)
Supplier Tel Email Country ProdList Advantage
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6288 58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd 15317229551 15151849396@163.com China 975 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Beijing Boorsen Biotechnology Co., Ltd 400-901-9800 18611424007 cis@bioss.com.cn China 9185 58
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 15850508050 cindy.huang@synzest.com China 11975 58
Shanghai Amole Biotechnology Co., Ltd. 13370042665 18916960931 2596183085@qq.com China 17234 58
Supplier Advantage
Shanghai EFE Biological Technology Co., Ltd. 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd 58
TargetMol Chemicals Inc. 58
Beijing Boorsen Biotechnology Co., Ltd 58
Nanjing Shizhou Biology Technology Co.,Ltd 58
Shanghai Amole Biotechnology Co., Ltd. 58

SRI 37892 Spectrum

SRI 37892(1030769-75-5)1HNMR

1030769-75-5 (SRI 37892) Related Search:

SRI 37892 N-[(1,1-Dimethylethoxy)carbonyl]-L-methionyl-L-α-aspartylglycyl-L-cysteinyl-L-α-glutamyl-L-leucine CHIR-99021 NCB-0846 Heparitin, sulfate
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SRI 37892 Benzamide, 4-(1H-benzimidazol-1-yl)-N-[4-(1,2,3,4-tetrahydro-2-oxo-6-quinolinyl)-2-thiazolyl]- 4-(1H-Benzo[d]imidazol-1-yl)-N-(4-(2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)thiazol-2-yl)benzamide SRI 37892, 10 mM in DMSO 1030769-75-5