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2,3-Dihydrothieno[3,4-b][1,4]dioxine-5,7-dicarbaldehyde

2,3-Dihydrothieno[3,4-b][1,4]dioxine-5,7-dicarbaldehyde structure

CAS No.: 211235-87-9

Chemical Name:: 2,3-Dihydrothieno[3,4-b][1,4]dioxine-5,7-dicarbaldehyde

Synonyms: 3,4-ethylenedioxythiophene-2,5-dicarboxaldehyde;2,3-Dihydrothieno[3,4-b][1,4]dioxine-5,7-dicarbaldehyde;Thieno[3,4-b]-1,4-dioxin-5,7-dicarboxaldehyde, 2,3-dihydro-

CBNumber:: CB6679257

Molecular Formula:: C8H6O4S

Molecular Weight:: 198.2

MDL Number:: MFCD01651767

MOL File:: 211235-87-9.mol

MSDS File:: SDS

Last updated:2026-09-12 18:54:21

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2,3-Dihydrothieno[3,4-b][1,4]dioxine-5,7-dicarbaldehyde Properties

Melting point	155 °C
Boiling point	403.4±45.0 °C(Predicted)
Density	1.511±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

2,3-Dihydrothieno[3,4-b][1,4]dioxine-5,7-dicarbaldehyde price More Price(20)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Matrix Scientific	302388	2,3-Dihydrothieno[3,4-b][1,4]dioxine-5,7-dicarbaldehyde	211235-87-9	100.00mg	$69	2026-05-19	Buy
Matrix Scientific	302388	2,3-Dihydrothieno[3,4-b][1,4]dioxine-5,7-dicarbaldehyde	211235-87-9	250.00mg	$132	2026-05-19	Buy
Matrix Scientific	302388	2,3-Dihydrothieno[3,4-b][1,4]dioxine-5,7-dicarbaldehyde	211235-87-9	1.00g	$324	2026-05-19	Buy
Synthonix	D48238	2,3-Dihydrothieno[3,4-b][1,4]dioxine-5,7-dicarbaldehyde 95+%	211235-87-9	100mg	$70	2026-05-06	Buy
Synthonix	D48238	2,3-Dihydrothieno[3,4-b][1,4]dioxine-5,7-dicarbaldehyde 95+%	211235-87-9	250mg	$150	2026-05-06	Buy

Product number	Packaging	Price	Buy
302388	100.00mg	$69	Buy
302388	250.00mg	$132	Buy
302388	1.00g	$324	Buy
D48238	100mg	$70	Buy
D48238	250mg	$150	Buy

2,3-Dihydrothieno[3,4-b][1,4]dioxine-5,7-dicarbaldehyde Chemical Properties, Uses, Production

Synthesis

68-12-2

126213-50-1

2,3-DIHYDROTHIENO[3,4-B][1,4]DIOXINE-5,7-DICARBALDEHYDE

211235-87-9

Under nitrogen protection, 3,4-ethylenedioxythiophene (EDOT, 3 g, 0.021 mol) was dissolved in anhydrous tetrahydrofuran (THF, 50 mL) and cooled to -78 °C. Subsequently, a solution of 1.6 M n-butyllithium (n-BuLi, 29 mL) was slowly added dropwise. After the dropwise addition, the reaction system was slowly warmed to 0 °C and stirred continuously at this temperature for 30 min. The reaction mixture was again cooled to -78 °C and quenched by the addition of dry N,N-dimethylformamide (DMF, 3.5 mL). The reaction mixture was transferred to room temperature conditions and stirring was continued for 2 hours. Upon completion of the reaction, the mixture was poured into crushed ice containing hydrochloric acid (pH=4) and a brown solid was precipitated. The solid was collected by filtration, washed with plenty of water and dried under vacuum. The crude product was recrystallized by cold methanol to afford the target compound 2,3-dihydrobenzo[3,4-b][1,4]dioxane-5,7-dibenzaldehyde (brown solid) in 75% yield. The product characterization data were as follows: IR (film) υmax: 2955, 2924, 2854, 1666, 1614, 1504, 1454, 1375 cm-1; 1H NMR (500 MHz, CDCl3): δ = 10.04 (s, 2H), 4.46 (s, 4H); 13C NMR (500 MHz, CDCl3): δ = 180.94, 147.15, 124.16, 65.15; Elemental analysis (C8H6O4S): Calculated values (%) C 48.48, H 3.04, S 16.14; Measured values: C 48.51, H 3.06, S 16.14.

References

[1] Journal of Molecular Liquids, 2017, vol. 225, p. 840 - 847
[2] Tetrahedron, 1999, vol. 55, # 40, p. 11745 - 11754
[3] Journal de Chimie Physique et de Physico-Chimie Biologique, 1998, vol. 95, # 6, p. 1234 - 1237
[4] Polymer, 2017, vol. 119, p. 274 - 284

2,3-Dihydrothieno[3,4-b][1,4]dioxine-5,7-dicarbaldehyde Preparation Products And Raw materials

Raw materials

N,N-Dimethylformamide Thieno[3,4-b]-1,4-dioxin-5,7-dicarbonitrile, 2,3-dihydro- Bromodichloromethane 3,4-Ethylenedioxythiophene n-Butyllithium

Tetrahydrofuran

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Preparation Products

2,3-Dihydrothieno[3,4-b][1,4]dioxine-5,7-dicarbaldehyde Suppliers

Global Suppliers ( 42)

Supplier	Tel	Email	Country	ProdList	Advantage
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
SynAsst Chemical.	021-60343070		China	12731	55
LABTER PHARMATECH(BEIJING) CO.,LTD	010-56330744 18310155299	sales@labter.com.cn	China	19999	55
Shanghai YuanYe Biotechnology Co., Ltd.	15026964105	2881489226@qq.com	China	89667	60
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131885	58
Aikon International Limited	025-58859352 19370895928	sales01@aikonchem.com	China	15078	58
Henan's chemical products co., LTD	0371-60919097 15378766539;	794449696@qq.com	China	5000	58
Shanghai Jizhi Biochemical Technology Co. Ltd.	021-4009004166/18616739031 18616739031	3007523370@qq.com	China	40000	58
Henan Lien Chemical Products Co., Ltd.	03716091-9097 13383857418;	1520689222@qq.com	China	4811	58
Yangzhou modier Electronic Materials Co., Ltd	13761402923 19975033992	market@modeltemol.com	China	7841	58

Supplier	Advantage
3B Pharmachem (Wuhan) International Co.,Ltd.	69
SynAsst Chemical.	55
LABTER PHARMATECH(BEIJING) CO.,LTD	55
Shanghai YuanYe Biotechnology Co., Ltd.	60
Amadis Chemical Company Limited	58
Aikon International Limited	58
Henan's chemical products co., LTD	58
Shanghai Jizhi Biochemical Technology Co. Ltd.	58
Henan Lien Chemical Products Co., Ltd.	58
Yangzhou modier Electronic Materials Co., Ltd	58

211235-87-9 (2,3-Dihydrothieno[3,4-b][1,4]dioxine-5,7-dicarbaldehyde) Related Search:

2,3-Dihydrothieno[3,4-b][1,4]dioxine-5,7-dicarbaldehyde 2,3-Dihydrothieno[3,4-b][1,4]dioxine-5-carbaldehyde 2,5-Thiophenedicarboxaldehyde 3,4-Dimethoxythiophene 7-carbamoyl-2H,3H-thieno[3,4-b][1,4]dioxine-5-carboxylic acid

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Thieno[3,4-b]-1,4-dioxin-5,7-dicarboxaldehyde, 2,3-dihydro- 3,4-ethylenedioxythiophene-2,5-dicarboxaldehyde 2,3-Dihydrothieno[3,4-b][1,4]dioxine-5,7-dicarbaldehyde 211235-87-9