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Z-Gly-Gly-Leu-AMC

Z-Gly-Gly-Leu-AMC Structure
Z-Gly-Gly-Leu-AMC structure
CAS No.
97792-39-7
Chemical Name:
Z-Gly-Gly-Leu-AMC
Synonyms
Z-GGL-AMC;Z-Gly-Gly-Leu-AMC;CBZ-Gly-Gly-Leu-AMC;Proteasome Substrate;PROTEASOME SUBSTRATE V, FLUOROGENIC;7-(N-benzyloxycarbonylglycyl-glycyl-leucyl)amino-4-methylcoumarin;7-(Nα-benzyloxycarbonyl-glycylglycyl-L-leucyl)amino-4-methylcoumarin;N-[(Phenylmethoxy)carbonyl]glycylglycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-leucinamide;L-Leucinamide, N-[(phenylmethoxy)carbonyl]glycylglycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-;Carbobenzoxy-Gly-Gly-Leu-7-amido-4-methylcoumarin, benzyloxycarbonyl-glycyl-glycyl-leucyl-7-amido-4-methylcoumarin
CBNumber:
CB6698322
Molecular Formula:
C28H32N4O7
Molecular Weight:
536.58
MDL Number:
MFCD00152029
MOL File:
97792-39-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:54:21
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Z-Gly-Gly-Leu-AMC Properties

Boiling point 877.646±65.00 °C(Press: 760.00 Torr)(predicted)
Density 1.281±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp. -15°C
form White powder.
pka 11.028±0.46(predicted)
Sequence {Cbz}-Gly-Gly-Leu-{AMC}
UNSPSC Code 12352204
NACRES NA.32

SAFETY

Risk and Safety Statements

WGK Germany  WGK 3
Storage Class 11 - Combustible Solids

Z-Gly-Gly-Leu-AMC price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth FG110537 Z-Gly-Gly-Leu-AMC 97792-39-7 500mg $900 2026-06-04 Buy
Biosynth FG110537 Z-Gly-Gly-Leu-AMC 97792-39-7 250mg $900 2026-06-04 Buy
Biosynth FG110537 Z-Gly-Gly-Leu-AMC 97792-39-7 100mg $900 2026-06-04 Buy
Biosynth FG110537 Z-Gly-Gly-Leu-AMC 97792-39-7 1000mg $1230 2026-06-04 Buy
Biosynth FG110537 Z-Gly-Gly-Leu-AMC 97792-39-7 2000mg $2140 2026-06-04 Buy
Product number Packaging Price Buy
FG110537 500mg $900 Buy
FG110537 250mg $900 Buy
FG110537 100mg $900 Buy
FG110537 1000mg $1230 Buy
FG110537 2000mg $2140 Buy

Z-Gly-Gly-Leu-AMC Chemical Properties,Uses,Production

Uses

Z-GGL-AMC is a fluorogenic substrate for the chymotrypsin-like activity of the 20S proteasome. It is a sensitive fluorogenic substrate for subtilisins BPN'' and Carlsberg.

Biological Activity

Z-Gly-Gly-Leu-7-amido-4-methylcoumarin (Z-Gly-Gly-Leu-AMC) is a fluorogenic peptide th at is used in analysis of protease and peptidase activity of proteasomes. Z-GGL-AMC has been noted as a particular substrate for chymotrypsin-like activity. It has low solubility and precipitates at 100μM.

Z-Gly-Gly-Leu-AMC synthesis

2566-19-0
62480-44-8
97792-39-7
Synthesis of Z-Gly-Gly-Leu-AMC from Cbz-Gly-Gly and H-Leu-AMC HCl

Z-Gly-Gly-Leu-AMC Preparation Products And Raw materials

Raw materials

H-Leu-AMC HCl Cbz-Gly-Gly

Preparation Products

Z-Gly-Gly-Leu-AMC Suppliers

Global( 52)Suppliers
Supplier Tel Email Country ProdList Advantage
GL Biochem (Shanghai) Ltd 21-61263452 13641803416 ymbetter@glbiochem.com China 9981 64
VDM Biochemicals 0330-2528181 sales@vdmbio.com United States 510 64
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Nanjing Leon Biological Technology Co., Ltd. 025-84523390 -127; 17705183659 sales@njleonbiotech.com China 5501 55
Nanjing Peptide Biotech Ltd. 025-58361106-805 15951641583 zhao.xu@njpeptide.com China 9976 55
Hangzhou Peptidego Biotech Co.,Ltd. 0571-87213919 15967184799 Eric@peptidego.com China 7872 58
Chengdu Peter-like Biotechnology Co., Ltd. 18108052721 2850505130@qq.com China 5037 58
Nanjing chengqimei Biotechnology Co., Ltd 19850819832 2173594524@qq.com China 2638 58
Nanchang Tianzhen Biotechnology Co., Ltd 13758194781 13173652190 522013271@qq.com China 2447 58
Nanjing TGpeptide Biotechnology Co.,Ltd. 18115476705 sales@tgpeptide.com China 3058 58
Supplier Advantage
GL Biochem (Shanghai) Ltd 64
VDM Biochemicals 64
Chemsky（shanghai）International Co.,Ltd. 50
Nanjing Leon Biological Technology Co., Ltd. 55
Nanjing Peptide Biotech Ltd. 55
Hangzhou Peptidego Biotech Co.,Ltd. 58
Chengdu Peter-like Biotechnology Co., Ltd. 58
Nanjing chengqimei Biotechnology Co., Ltd 58
Nanchang Tianzhen Biotechnology Co., Ltd 58
Nanjing TGpeptide Biotechnology Co.,Ltd. 58

97792-39-7(Z-Gly-Gly-Leu-AMC)Related Search:

Z-Gly-Tyr-NH2 Z-Gly-Gly-Arg-betana HCl Z-Gly-Gly-Phe-OH Z-Gly-Gly-Arg-AFC Z-Gly-Gly-Arg-AMC (acetate)
Z-Gly-Ala-His-βNA Z-Gly-Ala-Pro-βNA Z-Gly-Ala-Gln-AMC Z-Gly-Pro-Arg-PNA Z-Gly-Gly-Arg-7-amino-4-methylcoumarin
Z-Gly-Pro-Arg-AMC HCl Z-Gly-Gly-Leu-PNA Z-Gly-Pro-PNA Z-Gly-Ala-Met-AMC Z-Gly-Ala-His-AMC
Z-Gly-Gly-Phe-chloromethylketone Z-Gly-Pro-Arg-4MbNA acetate salt Z-Gly-Pro-Arg 7-amido-4-trifluoromethylcoumarin

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PROTEASOME SUBSTRATE V, FLUOROGENIC Z-GGL-AMC Carbobenzoxy-Gly-Gly-Leu-7-amido-4-methylcoumarin, benzyloxycarbonyl-glycyl-glycyl-leucyl-7-amido-4-methylcoumarin Proteasome Substrate 7-(N-benzyloxycarbonylglycyl-glycyl-leucyl)amino-4-methylcoumarin 7-(Nα-benzyloxycarbonyl-glycylglycyl-L-leucyl)amino-4-methylcoumarin L-Leucinamide, N-[(phenylmethoxy)carbonyl]glycylglycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)- N-[(Phenylmethoxy)carbonyl]glycylglycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-leucinamide CBZ-Gly-Gly-Leu-AMC Z-Gly-Gly-Leu-AMC 97792-39-7 C28H32N4O7 Proteasome substrate V