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ChemicalBook >> CAS DataBase List >>7-(4-Fluorobenzyl)-8-{[2-(1H-indol-3-yl)ethyl]amino}-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione

7-(4-Fluorobenzyl)-8-{[2-(1H-indol-3-yl)ethyl]amino}-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione

7-(4-Fluorobenzyl)-8-{[2-(1H-indol-3-yl)ethyl]amino}-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione Structure
7-(4-Fluorobenzyl)-8-{[2-(1H-indol-3-yl)ethyl]amino}-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione structure
CAS No.
885896-54-8
Chemical Name:
7-(4-Fluorobenzyl)-8-{[2-(1H-indol-3-yl)ethyl]amino}-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
Synonyms
PSB-KK1445;TOSLAB 870935;7-(4-Fluorobenzyl)-8-{[2-(1H-indol-3-yl)ethyl]amino}-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione;1H-Purine-2,6-dione, 7-[(4-fluorophenyl)methyl]-3,7-dihydro-8-[[2-(1H-indol-3-yl)ethyl]amino]-1,3-dimethyl-;7-[(4-fluorophenyl)methyl]-8-{[2-(1H-indol-3-yl)eth yl]amino}-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purin e-2,6-dione
CBNumber:
CB6700702
Molecular Formula:
C24H23FN6O2
Molecular Weight:
446.48
MDL Number:
MFCD07621015
MOL File:
Mol file
MSDS File:
SDS
Last updated:2026-09-12 18:54:22
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7-(4-Fluorobenzyl)-8-{[2-(1H-indol-3-yl)ethyl]amino}-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione Properties

solubility DMSO: Sparingly soluble: 1-10 mg/ml
form Solid
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501

7-(4-Fluorobenzyl)-8-{[2-(1H-indol-3-yl)ethyl]amino}-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 42093 PSB-KK1445 ≥95% 885896-54-8 5mg $51 2026-04-30 Buy
Cayman Chemical 42093 PSB-KK1445 ≥95% 885896-54-8 10mg $96 2026-04-30 Buy
Cayman Chemical 42093 PSB-KK1445 ≥95% 885896-54-8 25mg $228 2026-04-30 Buy
Cayman Chemical 42093 PSB-KK1445 ≥95% 885896-54-8 50mg $405 2026-04-30 Buy
ChemScene CS-1101713 PSB-KK1445 99.80% 885896-54-8 5mg $92 2026-06-04 Buy
Product number Packaging Price Buy
42093 5mg $51 Buy
42093 10mg $96 Buy
42093 25mg $228 Buy
42093 50mg $405 Buy
CS-1101713 5mg $92 Buy

7-(4-Fluorobenzyl)-8-{[2-(1H-indol-3-yl)ethyl]amino}-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione Chemical Properties, Uses, Production

Uses

PSB-KK1445 is a potent and selective GPR18 agonist with EC50s of 45.4 nM and 124 nM for human and mouse GPR18, respectively. PSB-KK1445 displays >200-fold selectivity versus both CB receptor subtypes, GPR55, and GPR183[1].

References

[1] Andhika B Mahardhika, et al. Potent, Selective Agonists for the Cannabinoid-like Orphan G Protein-Coupled Receptor GPR18: A Promising Drug Target for Cancer and Immunity. J Med Chem. 2024 Jun 27;67(12):9896-9926. DOI:10.1021/acs.jmedchem.3c02423

7-(4-Fluorobenzyl)-8-{[2-(1H-indol-3-yl)ethyl]amino}-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione Preparation Products And Raw materials

Raw materials

Preparation Products

7-(4-Fluorobenzyl)-8-{[2-(1H-indol-3-yl)ethyl]amino}-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione Suppliers

Global Suppliers ( 7)
Supplier Tel Email Country ProdList Advantage
Shanghai Beckham Medical Technology Co., Ltd 13816613772 huahero21@sina.com China 2996 55
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Supplier Advantage
Shanghai Beckham Medical Technology Co., Ltd 55
TargetMol Chemicals Inc. 58

885896-54-8 (7-(4-Fluorobenzyl)-8-{[2-(1H-indol-3-yl)ethyl]amino}-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione) Related Search:

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TOSLAB 870935 7-[(4-fluorophenyl)methyl]-8-{[2-(1H-indol-3-yl)eth yl]amino}-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purin e-2,6-dione 1H-Purine-2,6-dione, 7-[(4-fluorophenyl)methyl]-3,7-dihydro-8-[[2-(1H-indol-3-yl)ethyl]amino]-1,3-dimethyl- PSB-KK1445 7-(4-Fluorobenzyl)-8-{[2-(1H-indol-3-yl)ethyl]amino}-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione 885896-54-8