2-(2-Methylphenoxy)-4H-1,3,2-benzodioxaphosphorin 2-oxide
- CAS No.
- 1222-87-3
- Chemical Name:
- 2-(2-Methylphenoxy)-4H-1,3,2-benzodioxaphosphorin 2-oxide
- Synonyms
- cbdp;o-Tolyl saligenin phosphate;2-(o-cresyl)-4h-1,3,2-benzodioxaphoran-2-one;2-(2-cresyl)-4h-1-3-2-benzodioxaphosphorin-2-oxide;3,2-benzodioxaphosphorin,2-(o-tolyloxy)-4h-2-oxide;phosphoricacid,cyclicmethylene-o-phenyleneo-tolylester;3,2-benzodioxaphosphorin,2-(2-methylphenoxy)-4h-2-oxide;2-(2-METHYLPHENOXY)-4H-1,3,2-BENZODIOXAPHOSPHORIN 2-OXIDE;2-(o-Tolyloxy)-4H-benzo[d][1,3,2]dioxaphosphinine 2-Oxide;4H-1,3,2-Benzodioxaphosphorin, 2-(2-methylphenoxy)-, 2-oxide
- CBNumber:
- CB6765725
- Molecular Formula:
- C14H13O4P
- Molecular Weight:
- 276.22
- MDL Number:
- MFCD00798815
- MOL File:
- 1222-87-3.mol
- TDS File:
- TDS
2-(2-Methylphenoxy)-4H-1,3,2-benzodioxaphosphorin 2-oxide price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 30169 | CBDP | 55824-13-0 | 1mg | $95 | 2021-12-16 | Buy |
| Cayman Chemical | 30169 | CBDP | 55824-13-0 | 5mg | $380 | 2021-12-16 | Buy |
| aablocks | AA0016UM | 2-(o-Tolyloxy)-4H-benzo[d][1,3,2]dioxaphosphinine 2-Oxide 95% | 1222-87-3 | 100mg | $166 | 2026-05-28 | Buy |
| aablocks | AA0016UM | 2-(o-Tolyloxy)-4H-benzo[d][1,3,2]dioxaphosphinine 2-Oxide 95% | 1222-87-3 | 250mg | $343 | 2026-05-28 | Buy |
| aablocks | AA0016UM | 2-(o-Tolyloxy)-4H-benzo[d][1,3,2]dioxaphosphinine 2-Oxide 95% | 1222-87-3 | 1g | $538 | 2026-05-28 | Buy |
2-(2-Methylphenoxy)-4H-1,3,2-benzodioxaphosphorin 2-oxide Chemical Properties, Uses, Production
Uses
Plasma carboxylic-ester hydrolase (EC3.1.1.1) is a very important detoxification route for the toxic stereoisomers of soman. Detoxification is meant in the sense that if soman was bound to carbox-ylic-ester hydrolase, it was not free to inhibit acetylcholinesterase. CBDP (2-(2-Methylphenoxy)-4H-1,3,2-benzodioxaphosphorin 2-oxide) pretreatment, which inhibited irreversibly carboxylic-ester hydrolase activity without inhibiting phosphoryl phosphatase activity, potentiated the toxicity of soman in mice. In toxicity experiments, CBDP (0.5 mg/kg; iv 1 hr prior to soman) pretreatment potentiated the toxicity of C(±)P(±)-, C(+)P()-, and C()P()-soman to a similar degree[1].
References
[1] John G. Clement. “Stereoisomers of soman (pinacolyl methylphosphonofluoridate): Inhibition of serum carboxylic ester hydrolase and potentiation of their toxicity by CBDP (2-(2-methylphenoxy)-4H-1,3,2-benzodioxaphosphorin-2-oxide) in mice.” Toxicology and applied pharmacology 89 1 (1987): Pages 141-143.
2-(2-Methylphenoxy)-4H-1,3,2-benzodioxaphosphorin 2-oxide Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Beijing VSciChem Technology Co., Ltd. | 13811761079 | vscichem@163.com | China | 271 | 64 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Alfa Chemistry | +1-5166625404; | Info@alfa-chemistry.com | United States | 20000 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 +86-18019713315 | info@accelachem.com | United States | 21189 | 58 |
| Shanghai UCHEM Inc. | 18939844854 | sales6@myuchem.com | China | 4982 | 58 |
| Shanghai Haohong Scientific Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 39718 | 58 |
| SHAANXI?DIDEU?MEDICHEM CO.LTD | 17691182729 17392216275 | 1073@dideu.com | China | 9993 | 58 |
| Aikon International Limited | 025-58859352 18651614124 | 2881516338@qq.com | China | 9968 | 58 |
