ChemicalBook >> CAS DataBase List >>2-Methyl-3-trifluoromethylaniline
2-Methyl-3-trifluoromethylaniline
- CAS No.
- 54396-44-0
- Chemical Name:
- 2-Methyl-3-trifluoromethylaniline
- Synonyms
- 2-METHYL-3-(TRIFLUOROMETHYL)ANILINE;3-AMINO-2-METHYLBENZOTRIFLUORIDE;MABTF;2-Methyl-3-trifluoro;Flunixin EP Impurity B;Flunixin impurity B CRS;Flunixin Related CoMpound B;Methyl-3-(trifluoroMethyl)an;3-TRIFLUOROMETHYL-O-TOLUIDINE;Methyl-3-trifluoromethylanili
- CBNumber:
- CB6774574
- Molecular Formula:
- C8H8F3N
- Molecular Weight:
- 175.15
- MDL Number:
- MFCD00153216
- MOL File:
- 54396-44-0.mol
- MSDS File:
- SDS
Last updated:2026-01-13 11:23:53
| Product description | Number | Pack Size | Price |
| Flunixin impurity B European Pharmacopoeia (EP) Reference Standard | Y0000444 | 10 mg | $225 |
| Flunixin Related Compound B Pharmaceutical Secondary Standard; Certified Reference Material | PHR2823 | 50MG | $497 |
| 2-Methyl-3-(trifluoromethyl)aniline 95% | 375705 | 1g | $20.42 |
| Flunixin Related Compound B United States Pharmacopeia (USP) Reference Standard | 1274630 | 25mg | $1200 |
| 2-Methyl-3-trifluoromethylaniline >99.0%(GC) | M1328 | 1g | $31 |
| More product size | |||
| Melting point | 38-42 °C(lit.) |
|---|---|
| Boiling point | 62-64°C 4mm |
| Density | 1.237±0.06 g/cm3(Predicted) |
| Flash point | >210 °F |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| pka | 3.23±0.10(Predicted) |
| form | Crystalline Powder |
| color | White |
| BRN | 2832865 |
| InChI | InChI=1S/C8H8F3N/c1-5-6(8(9,10)11)3-2-4-7(5)12/h2-4H,12H2,1H3 |
| InChIKey | TWLDBACVSHADLI-UHFFFAOYSA-N |
| SMILES | C1(N)=CC=CC(C(F)(F)F)=C1C |
| CAS DataBase Reference | 54396-44-0(CAS DataBase Reference) |
| FDA UNII | 569607266B |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P305+P351+P338 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi,T,T+ | |||||||||
| Risk Statements | 36/37/38-26/27/28 | |||||||||
| Safety Statements | 26-36-24/25 | |||||||||
| RIDADR | 2811 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Toxic | |||||||||
| HazardClass | IRRITANT | |||||||||
| HazardClass | 6.1 | |||||||||
| HS Code | 29214990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
2-Methyl-3-trifluoromethylaniline price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0000444 | Flunixin impurity B European Pharmacopoeia (EP) Reference Standard | 54396-44-0 | 10 mg | $225 | 2025-07-31 | Buy |
| Sigma-Aldrich | PHR2823 | Flunixin Related Compound B Pharmaceutical Secondary Standard; Certified Reference Material | 54396-44-0 | 50MG | $497 | 2025-07-31 | Buy |
| Sigma-Aldrich | 375705 | 2-Methyl-3-(trifluoromethyl)aniline 95% | 54396-44-0 | 1g | $20.42 | 2025-07-31 | Buy |
| Sigma-Aldrich | 1274630 | Flunixin Related Compound B United States Pharmacopeia (USP) Reference Standard | 54396-44-0 | 25mg | $1200 | 2025-07-31 | Buy |
| TCI Chemical | M1328 | 2-Methyl-3-trifluoromethylaniline >99.0%(GC) | 54396-44-0 | 1g | $31 | 2025-07-31 | Buy |
2-Methyl-3-trifluoromethylaniline Chemical Properties,Uses,Production
Chemical Properties
White crystalline powder
Uses
2-Methyl-3-trifluoromethylaniline is a reactant in the synthesis of methylguanidine derivatives as prospective PET radioligands for the open channel of the NMDA receptor, linked to Alzheimer’s, epilepsy and other neurodegenerative disorders.
General Description
2-Methyl-3-(trifluoromethyl)aniline belongs to the trifluoromethylbenzene series.
Synthesis
A method for synthesizing 2-methyl-3-trifluoromethyl aniline, which takes 2-chloro-3-trifluoromethyl aniline as a raw material, introduces methylthio on the 2-chloro-3-trifluoromethyl aniline, reacts with sulfonyl chloride to convert the methylthio into chloromethyl, and then neutralizes and hydrogenates to obtain pure 2-Methyl-3-trifluoromethylaniline.
References
[1] Patent: US5248781, 1993, A
[2] Heterocycles, 1994, vol. 38, # 10, p. 2243 - 2246
Synthesis of 2-Methyl-3-trifluoromethylaniline from 2,2-DIMETHYL-N-[2-METHYL-3-(TRIFLUOROMETHYL)PHENYL]-PROPIONAMIDE
2-Methyl-3-trifluoromethylaniline Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 435)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Beijing Wisdom Chemicals Co., Ltd. | +8613701363759 | market@wisdomchem.com | China | 254 | 58 |
| SyncoZymes (Shanghai) Co., Ltd., | +8613681683526 | llchen@syncozymes.com | China | 40 | 58 |
| Hangzhou ICH Biofarm Co., Ltd | +86-0571-28186870; +undefined8613073685410 | sales@ichemie.com | China | 1006 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5242 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13676 | 58 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| Hi-Tech Chemistry Corp | 0519-86626038 | yuhh@hitechem.com | CHINA | 810 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21597 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
View Lastest Price from 2-Methyl-3-trifluoromethylaniline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-01-04 | 2-Methyl-3-trifluoromethylaniline (MTA)
54396-44-0
|
US $0.00 / kg | 1kg | 99.0% min | 10tons/month | Hangzhou ICH Biofarm Co., Ltd | |
 |
2025-05-26 | 2-Methyl-3-trifluoromethylaniline
54396-44-0
|
US $30.00-10.00 / kg | 10kg | 99% | 100000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2022-11-10 | 2-Methyl-3-trifluoromethylaniline
54396-44-0
|
US $0.00 / kg | 25kg | 99% | 20 tons | TAIZHOU DKD CHEMICAL CO., LTD. |
-
- 2-Methyl-3-trifluoromethylaniline (MTA)
54396-44-0
- US $0.00 / kg
- 99.0% min
- Hangzhou ICH Biofarm Co., Ltd
-
- 2-Methyl-3-trifluoromethylaniline
54396-44-0
- US $30.00-10.00 / kg
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- 2-Methyl-3-trifluoromethylaniline
54396-44-0
- US $0.00 / kg
- 99%
- TAIZHOU DKD CHEMICAL CO., LTD.
54396-44-0(2-Methyl-3-trifluoromethylaniline )Related Search:
MABTF
2-METHYL-3-(TRIFLUOROMETHYL)ANILINE
2-METHYL-3-TRIFLUOROMETHYL-PHENYLAMINE
3-TRIFLUOROMETHYL-O-TOLUIDINE
3-PERFLUOROMETHYL-2-METHYLANILINE
3-AMINO-2-METHYLBENZOTRIFLUORIDE
2-Methyl-3-Amino Benzotrifluoride
2-methyl-3-thifluoromethylaniline
2-methyl-3-trifluoromethylaniline(MTA)
2-Amino-6-trifluoromethyl toluene
2-Methyl-3-(trifluoromethyl)benzenamine
2-Methyl-3-Trifluoromethylaniline/2-Methyl-3-(Trifluoromethyl)Benzenamine
2-Methyl-3-Trifluoromethylanil
2-methyl-3-trifluoromethylaniline (intermediate of flunixin)
3-Amino-2-methylbenzotrifluoride 98%
Flunixin Meglumine EP Impurity B
3-Amino-2-methylbenzotrifluoride98%
2-METHYL-3-TRIFLUOROMETHYLANILINE (3-AMINO-2-METHYLBENZOTRIFLUORIDE)
3-Trifluoromethyl-2-methylaniline
2-Methyl-3-trifluoromethylaniline (3-Amino-2-methylbenzotrifluor
3-Amino-2-methylbenzotrifluoride
3-Trifluoromethyl-o-toluidine
2-Methyl-3-trifluoro
Flunixin Related CoMpound B
Methyl-3-(trifluoroMethyl)an
2-Methyl-3- threetrifluoroMethylaniline
BenzenaMine,2-Methyl-3-(trifluoroMethyl)-
Methyl-3-trifluoromethylaniline
Flunixin Meglumine Impurity 2（Flunixin Meglumine EP Impurity B）
Flunixin impurity B CRS
2-Methyl-3-trifluoromethylaniline>
Flunixin EP Impurity B
Amino-2-methylbenzotrifluoride
2-METHYL-3-TRIFLUOROMETHYLANILINE 54396-44-0
2-methyl-3(trifluoromethyl) aniline (ATFT)
Flunixin impurity BQ: What is
Flunixin impurity B Q: What is the CAS Number of
Flunixin impurity B Q: What is the storage condition of
Flunixin impurity B Q: What are the applications of
Flunixin impurity B
Flunixin Related Compound B (2-Methyl-3-(trifluoromethyl)aniline) (1274630)
Methyl-3-trifluoromethylanili
Flunixin USP Related Compound B
Flunixin Meglumine Impurity B
Flunixin Meglumine Impurity 5
54396-44-0
54369-44-0
CH3C6H3CF3NH2
Organic Building Blocks
Nitrogen Compounds
Building Blocks
Amines
C8
Amines
C8
Nitrogen Compounds
API intermediates
Trifluoromethylbenzene serise
