5-Nitro-2-piperidinobenzenecarbonitrile
- CAS No.
- 32188-75-3
- Chemical Name:
- 5-Nitro-2-piperidinobenzenecarbonitrile
- Synonyms
- 5-Nitro-2-(piperidin-1-yl);5-Nitro-2-piperidin-1-ylbenzonitrile;5-nitro-2-(1-piperidinyl)Benzonitrile;5-Nitro-2-piperidinobenzenecarbonitrile;Benzonitrile, 5-nitro-2-(1-piperidinyl)-
- CBNumber:
- CB6846725
- Molecular Formula:
- C12H13N3O2
- Molecular Weight:
- 231.25
- MDL Number:
- MFCD05365582
- MOL File:
- 32188-75-3.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
| Hazard Codes | Xi |
| HazardClass | IRRITANT |
| HS Code | 2933399990 |
5-Nitro-2-piperidinobenzenecarbonitrile price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 047240 | 5-Nitro-2-piperidinobenzenecarbonitrile | 32188-75-3 | 500.00mg | $118 | 2026-05-18 | Buy |
| Matrix Scientific | 047240 | 5-Nitro-2-piperidinobenzenecarbonitrile | 32188-75-3 | 1.00g | $151 | 2026-05-18 | Buy |
| Matrix Scientific | 047240 | 5-Nitro-2-piperidinobenzenecarbonitrile | 32188-75-3 | 5.00g | $346 | 2026-05-18 | Buy |
| aablocks | AA00C8C2 | 5-NITRO-2-PIPERIDINOBENZENECARBONITRILE >95% | 32188-75-3 | 1mg | $213 | 2026-05-28 | Buy |
| aablocks | AA00C8C2 | 5-NITRO-2-PIPERIDINOBENZENECARBONITRILE >95% | 32188-75-3 | 5mg | $228 | 2026-05-28 | Buy |
5-Nitro-2-piperidinobenzenecarbonitrile Chemical Properties, Uses, Production
Synthesis
110-89-4
16588-02-6
32188-75-3
The general procedure for the synthesis of 5-nitro-2-piperidinebenzonitrile from hexahydropyridine and 2-chloro-5-nitrobenzonitrile was as follows: a mixture of 2-chloro-5-nitrobenzonitrile (2 g, 10.96 mmol, 1 eq.), potassium carbonate (4.54 g, 32.7001 mmol, 3 eq.), piperidine (1.63 mL, 16.34 mmol, 1.5 eq.) and DMF ( 5 mL) mixture was stirred at 90°C for 3 hours until the reaction was complete. After the reaction was complete, the oil bath was removed. The reaction mixture was diluted with 100 mL of ethyl acetate (EA) and washed sequentially with saturated ammonium chloride solution and saturated sodium chloride solution. The aqueous phase was then extracted with ethyl acetate. All organic phases were combined and dried with anhydrous sodium sulfate. After filtration, the filtrate was concentrated to give the yellow solid product 5-nitro-2-piperidine benzonitrile (2.528 g, 99% yield).
References
[1] Patent: CN106892871, 2017, A. Location in patent: Paragraph 0135-0137
[2] Patent: US2003/203909, 2003, A1
[3] European Journal of Organic Chemistry, 2007, # 8, p. 1378 - 1383
[4] Patent: EP1176140, 2002, A1. Location in patent: Page 53
5-Nitro-2-piperidinobenzenecarbonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
5-Nitro-2-piperidinobenzenecarbonitrile Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Cool Pharm, Ltd | 021-60455363 18019463053 | sales@coolpharm.com | China | 8455 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
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| Zhejiang Lianshuo Biotechnology Co., Ltd. | 18616526224 | lianshuo@vip.126.com | China | 9605 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44871 | 58 |
