Iodoform
- CAS No.
- 75-47-8
- Chemical Name:
- Iodoform
- Synonyms
- CHI3;TRIIODOMETHANE;CHIT1;CHIT;CHITD;ioforme;Iodofrm;odoform;IODOFORM;FLJ00314
- CBNumber:
- CB6854229
- Molecular Formula:
- CHI3
Lewis structure
- Molecular Weight:
- 393.73
- MDL Number:
- MFCD00001069
- MOL File:
- 75-47-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 119 °C |
|---|---|
| Boiling point | 218°C |
| Density | 4.008 g/mL at 25 °C(lit.) |
| refractive index | 1.4975 (estimate) |
| storage temp. | -20°C |
| solubility | chloroform: soluble5% |
| form | Crystalline Powder |
| color | Bright yellow to dark yellow |
| Odor | char. pungent odor |
| biological source | mouse |
| Water Solubility | Insoluble. <0.1 g/100 mL at 24 ºC |
| Specific Heat Capacity | Cp(gas): 0.19 J/(g·K), at 25℃ |
| Sensitive | Light Sensitive |
| Merck | 14,5033 |
| BRN | 1697010 |
| Henry's Law Constant | 6.2×10-3 mol/(m3Pa) at 25℃, Fogg and Sangster (2003) |
| Exposure limits | PC-TWA:10 mg/m3 |
| Stability | Stable. Incompatible with strong oxidizing agents, reducing agents. May explode when heated. |
| Cosmetics Ingredients Functions | ANTIMICROBIAL |
| InChI | 1S/CHI3/c2-1(3)4/h1H |
| InChIKey | OKJPEAGHQZHRQV-UHFFFAOYSA-N |
| SMILES | IC(I)I |
| LogP | 3.510 (est) |
| Toxicology and Carcinogenesis | Bioassay of Iodoform for Possible Carcinogenicity (CASRN 75-47-8) |
| FDA 21 CFR | 175.105; 177.2600 |
| Indirect Additives used in Food Contact Substances | IODOFORM |
| CAS DataBase Reference | 75-47-8(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | KXI2J76489 |
| ATC code | D09AA13 |
| NIST Chemistry Reference | Methane, triiodo-(75-47-8) |
| EPA Substance Registry System | Iodoform (75-47-8) |
| UNSPSC Code | 12352203 |
| NACRES | NA.41 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H312-H315-H319-H332-H335 | |||||||||
| Precautionary statements | P264-P270-P280-P261-P271-P301+P312-P330-P302+P352-P312-P362+P364-P332+P313-P305+P351+P338-P337+P313-P304+P340-P403+P233-P405-P501 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 20/21/22-36/37/38 | |||||||||
| Safety Statements | 26-36/37-36/37/39-22-24/25 | |||||||||
| RIDADR | UN 1851 | |||||||||
| OEB | B | |||||||||
| OEL | TWA: 0.6 ppm (10 mg/m3) | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | PB7000000 | |||||||||
| F | 13 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29033990 | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
|||||||||
| Hazard Classifications | Acute Tox. 3 Inhalation Acute Tox. 4 Dermal Acute Tox. 4 Oral Aquatic Chronic 2 Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
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| Hazardous Substances Data | 75-47-8(Hazardous Substances Data) | |||||||||
| Toxicity | LD50 s.c. in mice: 1.6 mmoles/kg (Kutob, Plaa) | |||||||||
| NFPA 704 |
|
Iodoform price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 109452 | Iodoform 99% | 75-47-8 | 5g | $46.3 | 2026-04-30 | Buy |
| Sigma-Aldrich | 109452 | Iodoform 99% | 75-47-8 | 100g | $93.2 | 2026-04-30 | Buy |
| Sigma-Aldrich | SAB2501721 | Anti-CHIT1 antibody produced in goat affinity isolated antibody, buffered aqueous solution | 75-47-8 | 100μg | $586 | 2025-07-31 | Buy |
| Sigma-Aldrich | SAB1402723 | Monoclonal Anti-CHIT1 antibody produced in mouse clone 1D11, purified immunoglobulin, buffered aqueous solution | 75-47-8 | 100μg | $541 | 2025-07-31 | Buy |
| Usbiological | 280683 | Iodoform Asreported | 75-47-8 | 25g | $333 | 2026-06-03 | Buy |
Iodoform Chemical Properties, Uses, Production
Description
Iodoform is a stable, pale yellow crystalline solid. It is volatile with a characteristic pungent, unpleasant and penetrating odour, but with a sweetish taste. It is incompatible with strong oxidising agents, reducing agents, lithium, and metallic salts such as mercuric oxide, silver nitrate, strong bases, calomel, and tannin. Reports indicate that earlier iodoform was in use as a disinfectant and as an antiseptic or dressing and healing of wounds and sores for pets. Iodoform is the active ingredient in many antiseptic or dressing powders used for dogs and cats to prevent infection.
Chemical Properties
yellow solid with a characteristic pungent and
Chemical Properties
Iodoform is a yellow or greenish-yellow powder or crystalline solid that is volatile with steam and contains 96.69% iodine. It has a very characteristic pungent odor. An odor threshold of 0.005 ppm has been reported.
Uses
Iodoform has limited use as a chemical intermediate and for medicinal purposes as disinfectant and antiseptic and has been used in veterinary medicine.
Uses
Triiodomethane is a crystalline compound commonly used as a disinfectant. It can be used in the process of removing heavy metals such as mercury from fuids.
Uses
It is used as a topical anti-infective, applied to the skin.
Definition
A yellow crystalline
compound made by warming ethanal with
an alkaline solution of an iodide:
CH3CHO + 3I– + 4OH– → CHI3 +
HCOO– + 3H2O
The reaction also occurs with all ketones of
general formula CH3COR (R is an alkyl
group) and with secondary alcohols
CH3CH(OH)R. Iodoform is used as a test
for such reactions (the iodoform reaction).
General Description
Bright yellow or yellow powder or crystals. Penetrating odor. Unctuous touch. Odor threshold 0.4 ppb.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
Iodoform decomposes at high temperatures. Decomposes slowly in light at room temperature. Reacts violently with lithium. Is incompatible with mercuric oxide, calomel, silver nitrate, tannin, and balsam Peru. Is also incompatible with strong bases, strong oxidizing agents and magnesium. Vigorous reactions occur with acetone in the presence of solid potassium hydroxide or calcium hydroxide, hexamethylenetetramine at 352° F, mercury(I) fluoride and finely divided reduced silver.
Hazard
Irritant. Decomposes violently at 400F (204C).
Health Hazard
Iodoform causes central nervous system depression and damage to the kidneys, liver, and heart.
Fire Hazard
Literature sources indicate that Iodoform is nonflammable.
Biochem/physiol Actions
Iodoform is an iodine containing compound, which is used in antiseptic applications in the medical and veterinary medicine fields. Iodoform improves fermentation in the biomass ensilage conversion system by improving lactic acid production and inhibiting butyric fermentation.
Carcinogenicity
Iodoform has been included in the NCI daily bioassay program. According to their summary: the high and low time-weighted average daily dosages of iodoform were, respectively, 142 and 71 mg/kg for male rats, 55 and 27 mg/kg for female rats, and 93 and 47 mg/kg for male and female mice. A significant positive association between dosage and mortality was observed in male rats but not in female rats or in mice of either sex. Adequate numbers of animals in all groups survived sufficiently long to be at risk from late-developing tumors. No statistical significance could be attributed to the incidences of any neoplasms in rats or mice of either sex when compared to their respective controls. Under the conditions of this bioassay, no convincing evidence was provided for the carcinogenicity of iodoform in Osborne–Mendel rats or B6C3F1 mice.
Purification Methods
Crystallise it from MeOH, EtOH or EtOH/EtOAc. It is steam volatile. It is a disinfectant. [Beilstein 1 IV 97.]
Iodoform Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan kemike Biomedical Technology Co., Ltd | 027-13163388153 13163388153 | yeqiu416@163.com | China | 8787 | 58 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29977 | 65 |
| anqing sinosynth new materials technology co,ltd | 18055625120 | aqsinosynth@163.com | China | 485 | 58 |
| Chengdu HuaXia Chemical Reagent Co. Ltd | 400-1166-196 13458535857 | cdhxsj@163.com | China | 13323 | 58 |
| Shanxi jiaernuo Biotechnology Co.,LTD. | 19992526222 13992350171 | 540492555@qq.com | China | 23 | 58 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TAIYUAN RHF CO.,LTD. | +86 351 7031519 | sales@RHFChem.com | China | 2334 | 56 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
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- Jul 17,2026
View Latest Price from Iodoform manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | Iodoform USP/EP/BP
75-47-8
|
$1.10 | 1g | 99.9% | 100 Tons min | Dideu Industries Group Limited | |
 |
2026-05-28 | Iodoform
75-47-8
|
$2.00-5.00 | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2024-10-06 | Iodoform
75-47-8
|
$490.00 | 98 | 1000 Kg | R&D Scientific Inc. |
-
- Iodoform USP/EP/BP
75-47-8
- $1.10
- 99.9%
- Dideu Industries Group Limited
-
- Iodoform
75-47-8
- $2.00-5.00
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- Iodoform
75-47-8
- $490.00
- 98
- R&D Scientific Inc.
