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Masoprocol

CAS No.
27686-84-6
Chemical Name:
Masoprocol
Synonyms
CHX-100;masoprocol;NORHYDROGUAIARETICACID;Masoprocol(nordihydroguaiaretic);meso-4,4'-(2,3- Dimethyltetramethylene)dipyrocatechol;(R*,S*)-4,4'-(2,3-dimethylbutane-1,4-diyl)bispyrocatechol;4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]benzene-1,2-diol;4,4'-((2R,3S)-2,3-DiMethylbutane-1,4-diyl)bis(benzene-1,2-diol);4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyrocatechol;rel-4,4'-((2R,3S)-2,3-Dimethylbutane-1,4-diyl)bis(benzene-1,2-diol)
CBNumber:
CB6855231
Molecular Formula:
C18H22O4
Molecular Weight:
302.36
MDL Number:
MFCD00866548
MOL File:
27686-84-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-11 15:21:01
Product description Number Pack Size Price
Masoprocol XN163193 50mg $239
Masoprocol XN163193 100mg $380
Masoprocol XN163193 250mg $715
Masoprocol XN163193 500mg $960
Masoprocol XN163193 1000mg $1520
More product size

Masoprocol Properties

Melting point 185.5°C
Boiling point 526.5±45.0 °C(Predicted)
Density 1.241±0.06 g/cm3(Predicted)
storage temp. 2-8°C
form Solid
pka 9.56±0.10(Predicted)
color Off-white to light yellow
LogP 3.710 (est)
EWG's Food Scores 4
NCI Dictionary of Cancer Terms masoprocol
FDA UNII 7BO8G1BYQU
NCI Drug Dictionary masoprocol
ATC code L01XX10
EPA Substance Registry System 1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-, (R*,S*)- (27686-84-6)

SAFETY

Risk and Safety Statements

TSCA  TSCA listed

Masoprocol price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth XN163193 Masoprocol 27686-84-6 50mg $239 2026-06-05 Buy
Biosynth XN163193 Masoprocol 27686-84-6 100mg $380 2026-06-05 Buy
Biosynth XN163193 Masoprocol 27686-84-6 250mg $715 2026-06-05 Buy
Biosynth XN163193 Masoprocol 27686-84-6 500mg $960 2026-06-05 Buy
Biosynth XN163193 Masoprocol 27686-84-6 1000mg $1520 2026-06-05 Buy
Product number Packaging Price Buy
XN163193 50mg $239 Buy
XN163193 100mg $380 Buy
XN163193 250mg $715 Buy
XN163193 500mg $960 Buy
XN163193 1000mg $1520 Buy

Masoprocol Chemical Properties,Uses,Production

Description

Masoprocol is a lipoxygenase inhibitor launched as a topical agent for the treatment of solar or actinic keratoses. It is the first new topical treatment for pre-malignant skin lesions introduced in twenty years. Masoprocol is obtained from the Larrea tridentata plant and is also under investigation for the treatment of lung, breast, colon and ovarian cancers.

Chemical Properties

Crystallized from acetic acid, melting point 185~186°C. UV maximum absorption (methanol): 283, 218nm (ε6660, 13400). Soluble in ethanol, methanol, ether or concentrated sulfuric acid, slightly soluble in hot water or chloroform, insoluble in petroleum ether, benzene, toluene or dilute hydrochloric acid. Soluble in dilute alkaline solution and becomes red.

Originator

Chemex (U.S.A.)

Uses

Antineoplastic.

Definition

ChEBI: Masoprocol is the meso-form of nordihydroguaiaretic acid. An antioxidant found in the creosote bush, Larrea divaricata, it is a potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. It also inhibits (though to a lesser extent) formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase. It has a role as an antineoplastic agent, a lipoxygenase inhibitor, a hypoglycemic agent and a metabolite.

brand name

Actinex (University Of Arizonia Cancer Center).

Masoprocol Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 26)Suppliers
Supplier Tel Email Country ProdList Advantage
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
TargetMol Chemicals Inc.
+17819995354 marketing@targetmol.com United States 19956 58
Chongqing jooe co., ltd
+undefined86-15223382610 info@jooe.com China 15976 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131957 58
NCE Biomedical Co.,Ltd. 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988 China 1493 55
LETOPHARM LIMITED +86-21-5821 5861 sales@letopharm.com China 2384 58
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903 3008007409@qq.com China 89686 60
Aikon International Limited 025-58859352 19370895928 sales01@aikonchem.com China 15082 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24955 58
Shaanxi Dideu Newmaterial Co., Ltd. 029-63373950 17392216152 1050@dideu.com China 9998 58

View Lastest Price from Masoprocol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Masoprocol pictures 2026-05-11 Masoprocol
27686-84-6
$99.00 99.76% 10g TargetMol Chemicals Inc.
  • Masoprocol pictures
  • Masoprocol
    27686-84-6
  • $99.00
  • 99.76%
  • TargetMol Chemicals Inc.
masoprocol 4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]benzene-1,2-diol (R*,S*)-4,4'-(2,3-dimethylbutane-1,4-diyl)bispyrocatechol Masoprocol(nordihydroguaiaretic) NORHYDROGUAIARETICACID CHX-100 meso-4,4'-(2,3- Dimethyltetramethylene)dipyrocatechol 4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]benzene-1,2-diol 4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol 4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyrocatechol 4,4'-((2R,3S)-2,3-DiMethylbutane-1,4-diyl)bis(benzene-1,2-diol) rel-4,4'-((2R,3S)-2,3-Dimethylbutane-1,4-diyl)bis(benzene-1,2-diol) 27686-84-6