Masoprocol
- CAS No.
- 27686-84-6
- Chemical Name:
- Masoprocol
- Synonyms
- CHX-100;masoprocol;NORHYDROGUAIARETICACID;Masoprocol(nordihydroguaiaretic);meso-4，4'-(2，3- Dimethyltetramethylene)dipyrocatechol;(R*,S*)-4,4'-(2,3-dimethylbutane-1,4-diyl)bispyrocatechol;4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]benzene-1,2-diol;4,4'-((2R,3S)-2,3-DiMethylbutane-1,4-diyl)bis(benzene-1,2-diol);4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyrocatechol;rel-4,4'-((2R,3S)-2,3-Dimethylbutane-1,4-diyl)bis(benzene-1,2-diol)
- CBNumber:
- CB6855231
- Molecular Formula:
- C18H22O4
- Molecular Weight:
- 302.37
- MDL Number:
- MFCD00866548
- MOL File:
- 27686-84-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 185.5°C |
|---|---|
| Boiling point | 526.5±45.0 °C(Predicted) |
| Density | 1.241±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| form | Solid |
| pka | 9.56±0.10(Predicted) |
| color | Off-white to light yellow |
| LogP | 3.710 (est) |
| EWG's Food Scores | 4 |
| NCI Dictionary of Cancer Terms | masoprocol |
| FDA UNII | 7BO8G1BYQU |
| NCI Drug Dictionary | masoprocol |
| ATC code | L01XX10 |
| EPA Substance Registry System | 1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-, (R*,S*)- (27686-84-6) |
Masoprocol price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | XN163193 | Masoprocol | 27686-84-6 | 50mg | $239 | 2026-06-05 | Buy |
| Biosynth | XN163193 | Masoprocol | 27686-84-6 | 100mg | $380 | 2026-06-05 | Buy |
| Biosynth | XN163193 | Masoprocol | 27686-84-6 | 250mg | $715 | 2026-06-05 | Buy |
| Biosynth | XN163193 | Masoprocol | 27686-84-6 | 500mg | $960 | 2026-06-05 | Buy |
| Biosynth | XN163193 | Masoprocol | 27686-84-6 | 1000mg | $1520 | 2026-06-05 | Buy |
Masoprocol Chemical Properties,Uses,Production
Description
Masoprocol is a lipoxygenase inhibitor launched as a topical agent for the treatment of solar or actinic keratoses. It is the first new topical treatment for pre-malignant skin lesions introduced in twenty years. Masoprocol is obtained from the Larrea tridentata plant and is also under investigation for the treatment of lung, breast, colon and ovarian cancers.
Chemical Properties
Crystallized from acetic acid, melting point 185～186°C. UV maximum absorption (methanol): 283, 218nm (ε6660, 13400). Soluble in ethanol, methanol, ether or concentrated sulfuric acid, slightly soluble in hot water or chloroform, insoluble in petroleum ether, benzene, toluene or dilute hydrochloric acid. Soluble in dilute alkaline solution and becomes red.
Originator
Chemex (U.S.A.)
Uses
Antineoplastic.
Definition
ChEBI: Masoprocol is the meso-form of nordihydroguaiaretic acid. An antioxidant found in the creosote bush, Larrea divaricata, it is a potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. It also inhibits (though to a lesser extent) formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase. It has a role as an antineoplastic agent, a lipoxygenase inhibitor, a hypoglycemic agent and a metabolite.
brand name
Actinex (University Of Arizonia Cancer Center).
Masoprocol Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| NCE Biomedical Co.,Ltd. | 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988 | China | 1490 | 55 | |
| LETOPHARM LIMITED | +86-21-5821 5861 | sales@letopharm.com | China | 2374 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Aikon International Limited | 025-58859352 19370895928 | sales01@aikonchem.com | China | 15078 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Shaanxi Dideu Newmaterial Co., Ltd. | 029-63373950 17392216152 | 1035@dideu.com | China | 9991 | 58 |
| Shanghai Tachizaki Biomedical Research Center | 18014399201 | sales@chemlab-tachizaki.com | China | 2936 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| Chengdu Peter-like Biotechnology Co., Ltd. | 028-81700200 13308200041 | 2851167782@qq.com | China | 10763 | 58 |
View Lastest Price from Masoprocol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-15 | Masoprocol
27686-84-6
|
$99.00 | 99.76% | 10g | TargetMol Chemicals Inc. |
-
- Masoprocol
27686-84-6
- $99.00
- 99.76%
- TargetMol Chemicals Inc.
