cholesta-3,5-dien-7-one
- CAS No.
- 567-72-6
- Chemical Name:
- cholesta-3,5-dien-7-one
- Synonyms
- CAY10787;cholesta-3,5-dien-7-one;Cholesta-3,5-diene-7-one;7-Ketocholesta-3,5-diene;Cholesta-3,5-diene-7-one-d7
- CBNumber:
- CB6880301
- Molecular Formula:
- C27H42O
- Molecular Weight:
- 382.62
- MDL Number:
- MFCD00184936
- MOL File:
- 567-72-6.mol
- MSDS File:
- SDS
| Melting point | 114 °C |
|---|---|
| Boiling point | 494.0±12.0 °C(Predicted) |
| Density | 0.99±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Chloroform: 10 mg/ml |
| form | A crystalline solid |
| FDA UNII | 6XJ9029P2X |
cholesta-3,5-dien-7-one price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | R209902 | CHOLESTA-3,5-DIEN-7-ONE AldrichCPR | 567-72-6 | 1 unit | $191 | 2026-04-30 | Buy |
| Sigma-Aldrich | R209902 | CHOLESTA-3,5-DIEN-7-ONE AldrichCPR | 567-72-6 | 1MG | $174 | 2024-03-01 | Buy |
| Cayman Chemical | 34320 | Cholesta-3,5-dien-7-one ≥95% | 567-72-6 | 1mg | $121 | 2026-04-30 | Buy |
| Cayman Chemical | 34320 | Cholesta-3,5-dien-7-one ≥95% | 567-72-6 | 5mg | $508 | 2026-04-30 | Buy |
| Cayman Chemical | 34320 | Cholesta-3,5-dien-7-one ≥95% | 567-72-6 | 10mg | $951 | 2026-04-30 | Buy |
cholesta-3,5-dien-7-one Chemical Properties, Uses, Production
Uses
Delta3,5-cholestadien-7-one is an oxysterol and a negative allosteric modulator of GABAA receptors. Delta3,5-cholestadien-7-one reduces GABA-induced currents in HEK cells expressing α1β1γ2 or α4β3γ2 subunit-containing GABAA receptors with IC50 values of 1.5 and 1 μM, respectively. Delta3,5-cholestadien-7-one reduces GABA-induced depolarization of peptidergic and non-peptidergic nociceptors, C-LTMRs, and cold thermosensors in isolated mouse dorsal root ganglion (DRG) neurons[1][2].
References
[1] Hahn M, et al. Cholest-3,5-dien-7-one formation in peroxidized human plasma as an indicator of lipoprotein cholesterol peroxidation potential. Biochim Biophys Acta. 1995 Apr 6;1255(3):341-3. DOI:10.1016/0005-2760(95)00004-v
cholesta-3,5-dien-7-one Preparation Products And Raw materials
Raw materials
Preparation Products
cholesta-3,5-dien-7-one Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Clearsynth Labs Limited | +91-22-26355700 | info@clearsynth.com | India | 9656 | 58 |
| Nanjing Haolv Biotechnology Co.,Ltd | 025-84622273 17361806303 | kexin.zhou@haolvbiotech.com | China | 3009 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Yancheng Tongming Biotechnology Co., Ltd. | 15195160625 | 2863565288@qq.com | China | 5178 | 58 |
| Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 029-029-81120477 17792793610 | 1033@dideu.com | China | 9990 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Shanghai Saikerui Biotechnology Co. , Ltd. | 021-58000709 13120558703 | sales@scrbio.com | China | 9873 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| hubei PharmaStandard Co., Ltd. | 027-19050701 13545374703 | cbbspring@163.com | China | 424 | 58 |
| Z-trans Biochemistry Technology (Suzhou) Co.,Ltd | 0512-66317708 13372112871 | huijuan@zitrans.cn | China | 2260 | 58 |
