clopenthixol
- CAS No.
- 982-24-1
- Chemical Name:
- clopenthixol
- Synonyms
- N-746;AY-62021;Sordinol;NSC-64087;Neo-ciatyl;Aids115500;Aids-115500;clopenthixol;CHLORPENTHIXOL;clopenthixol USP/EP/BP
- CBNumber:
- CB6924052
- Molecular Formula:
- C22H25ClN2OS
- Molecular Weight:
- 400.96
- MDL Number:
- MFCD00866662
- MOL File:
- 982-24-1.mol
- MSDS File:
- SDS
| Boiling point | 577.4±50.0 °C(Predicted) |
|---|---|
| Density | 1.289±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | pKa 6.69 (Uncertain) |
| EWG's Food Scores | 1 |
| FDA UNII | 0A432D932A |
| ATC code | N05AF02 |
clopenthixol price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | AAA98224 | Clopenthixol | 982-24-1 | 25mg | $873.25 | 2026-06-04 | Buy |
| Biosynth | AAA98224 | Clopenthixol | 982-24-1 | 50mg | $1397 | 2026-06-04 | Buy |
| Biosynth | AAA98224 | Clopenthixol | 982-24-1 | 100mg | $1945 | 2026-06-04 | Buy |
| ChemScene | CS-0138466 | Clopenthixol 98.04% | 982-24-1 | 5mg | $34 | 2026-06-04 | Buy |
| ChemScene | CS-0138466 | Clopenthixol 98.04% | 982-24-1 | 10mg | $54 | 2026-06-04 | Buy |
clopenthixol Chemical Properties, Uses, Production
Chemical Properties
Colorless paste. Soluble in methanol, insoluble in ether. cis(Z)-configuration: [53772-83-1]. Crystallized, melting point 84-85°C. Clopenthixol Dihydrochloride: C22H25C1N2OS2HCl.[633-59-0]. Crystallized from ethanol, melting point 250~260°C (decomposition). Extremely soluble in water, insoluble in alcohol, several insoluble in other organic solvents. Acute toxicity LD50 male mice (mg/kg): 111 IV. cis(Z)-dihydrochloride: [58045-23-1]. Crystalline, melting point 250~260°C (decomposition). Acute toxicity LD50 male mice (mg/kg): 105 IV.
Originator
Ciatyl,Tropon,W. Germany,1961
Uses
Antipsychotic.
Definition
ChEBI: A thioxanthene derivative having a chloro substituent at the 2-position and an alkylidene group at the 10-position with undefined double bond stereochemistry.
Manufacturing Process
A mixture of 31 5 g (0.1 mol) of 2-chloro-9-(3'-dimethylaminopropylidene)- thiaxanthene (MP 97°C) and 100 g of N-(β-hydroxyethyl)piperazine is heated to 130°C and boiled under reflux at this temperature for 48 hours. After cooling,the excess of N-(β-hydroxyethyl)piperazine is evaporated in vacuo, and the residue is dissolved in ether. The ether phase is washed with water and extracted with dilute acetic acid, and 2-chloro-9-[3'-N-(N'-β- hydroxyethyl)piperazinylpropylidene]-thiaxanthene separated from the aqueous acetic acid solution by addition of dilute sodium hydroxide solution to basic reaction. The free base is extracted with ether, the ether phase dried over potassium carbonate, the ether evaporated and the residue dissolved in absolute ethanol. By complete neutralization of the ethanolic solution with a solution of dry hydrogen chloride in absolute ethanol, the dihydrochloride of 2- chloro-9-[3'-N-(N'-β-hydroxyethyl)piperazinylpropylidene]-thiaxanthene is produced and crystallizes out as a white substance melting at about 250°C to 260°C with decomposition. The yield is 32 g.
Therapeutic Function
Antipsychotic
clopenthixol Preparation Products And Raw materials
Raw materials
Preparation Products
clopenthixol Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| LGM Pharma | 1-(800)-881-8210 | inquiries@lgmpharma.com | United States | 2110 | 70 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Dideu Industries Group Limited | +8617392712697 | 1022@dideu.com | China | 29091 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52693 | 58 |
| Guangzhou Younan Technology Co., Ltd | 020-82000279 18988941452 | YN_research@163.com | China | 2984 | 58 |
| Shanghai Botuo Biotechnology Co., LTD | 16621358918 | botuopharma888@163.com | China | 9192 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Shanghai Tachizaki Biomedical Research Center | 18014399201 | sales@chemlab-tachizaki.com | China | 2934 | 58 |
| Baoji Didu Pharmaceutical and Chemical Co., Ltd | 029-81145305 17791533577 | 1021@dideu.com | China | 9997 | 58 |
| Chengdu Peter-like Biotechnology Co., Ltd. | 028-81700200 13308200041 | 2851167782@qq.com | China | 10763 | 58 |
View Latest Price from clopenthixol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | clopenthixol USP/EP/BP
982-24-1
|
$1.10 | 1g | 99.9% | 100 Tons min | Dideu Industries Group Limited | |
 |
2026-04-21 | Clopenthixol
982-24-1
|
$1520.00-2500.00 | 10g | TargetMol Chemicals Inc. |
-
- clopenthixol USP/EP/BP
982-24-1
- $1.10
- 99.9%
- Dideu Industries Group Limited
-
- Clopenthixol
982-24-1
- $1520.00-2500.00
- TargetMol Chemicals Inc.
