GABAPENTIN-D4
- CAS No.
- 1185039-20-6
- Chemical Name:
- GABAPENTIN-D4
- Synonyms
- GOE-3450-d;GOE-3450-d4;Neurontin-d4;GABAPENTIN-D4;D4-Gabapentin;[2H4]-Gabapentin;Gabapentin-D4, 1mg/ml in Methanol;Gabapentin-D4, 0.1mg/ml in Methanol;Gabapentin-d4 (100 μg/mL in Methanol);1-(Aminomethyl)cyclohexaneacetic Acid-d4
- CBNumber:
- CB6990626
- Molecular Formula:
- C9H13D4NO2
- Molecular Weight:
- 175.26
- MDL Number:
- MFCD08704961
- MOL File:
- Mol file
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 179-181°C |
|---|---|
| Boiling point | 314.438±15.00 °C(Press: 760.00 Torr)(predicted) |
| Density | 1.058±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) |
| storage temp. | -20°C Freezer, Under Inert Atmosphere |
| solubility | Methanol (Slightly), Water (Slightly) |
| form | Solid |
| pka | 4.725±0.10(predicted) |
| color | White to Off-White |
| Stability | Hygroscopic |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H315-H319-H360-H335 | |||||||||
| Precautionary statements | P201-P202-P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P308+P313-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501 | |||||||||
| NFPA 704 |
|
GABAPENTIN-D4 price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 18254 | Gabapentin-d4 ≥95% | 1185039-20-6 | 500μg | $116 | 2026-04-30 | Buy |
| Cayman Chemical | 18254 | Gabapentin-d4 ≥95% | 1185039-20-6 | 1mg | $220 | 2026-04-30 | Buy |
| TRC | TRC-G117252-1MG | Gabapentin-d4 >95%(HPLC) | 1185039-20-6 | 1mg | $260 | 2026-06-03 | Buy |
| TRC | TRC-G117252-10MG | Gabapentin-d4 >95%(HPLC) | 1185039-20-6 | 10mg | $2013 | 2026-06-03 | Buy |
| ChemScene | CS-0182781 | Gabapentin-d4 99.44% | 1185039-20-6 | 1mg | $282 | 2026-06-04 | Buy |
GABAPENTIN-D4 Chemical Properties, Uses, Production
Description
Gabapentin-d4 is intended for use as an internal standard for the quantification of gabapentin by GC- or LC-MS. Gabapentin is a γ-aminobutyric acid (GABA) analogue that acts as an anticonvulsant. It does not bind to GABA receptors, does not influence neural uptake of GABA, and does not inhibit the GABA-metabolizing enzyme, GABA transaminase. Unlike GABA, which does not pass through the blood-brain barrier, gabapentin penetrates into the central nervous system and binds to the α2δ-type voltage-gated calcium channels. Formulations containing gabapentin have been used to treat neuropathic pain caused by complex regional pain syndrome type one, cancer, and HIV as well as to control dysesthesias in patients with multiple sclerosis.
Chemical Properties
White Solid
Uses
Amino acid structurally related to -Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Gabapentin-d4 can be used as an anticonvulsant.
References
[1] ANTON C VAN DE VUSSE. Randomised controlled trial of gabapentin in Complex Regional Pain Syndrome type 1 [ISRCTN84121379].[J]. BMC Neurology, 2004, 4: 13. DOI: 10.1186/1471-2377-4-13
[2] K HAHN. A placebo-controlled trial of gabapentin for painful HIV-associated sensory neuropathies.[J]. Journal of Neurology, 2004, 251 10: 1260-1266. DOI: 10.1007/s00415-004-0529-6
[3] LUU M. Gabapentin for neuropathic cancer pain: a randomized controlled trial from the gabapentin cancer pain study group[J]. Douleurs, 2005, 6 1: Pages 49-50. DOI: 10.1016/s1624-5687(05)80227-6
[4] N S GEE. The novel anticonvulsant drug, gabapentin (Neurontin), binds to the alpha2delta subunit of a calcium channel.[J]. The Journal of Biological Chemistry, 1996, 271 10: 5768-5776. DOI: 10.1074/jbc.271.10.5768
[5] KAREN L GOA Eugene M S. Gabapentin. A review of its pharmacological properties and clinical potential in epilepsy.[J]. Drugs, 1993, 46 3: 409-427. DOI: 10.2165/00003495-199346030-00007
GABAPENTIN-D4 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Clearsynth Canada Inc. | +1.415.685.4395 | enquiry@clearsynth.com | Canada | 912 | 58 |
| Nanjing Haolv Biotechnology Co.,Ltd | 025-84622273 17361806303 | kexin.zhou@haolvbiotech.com | China | 3009 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 | sales@rrkchem.com | China | 57336 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19935 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| ChengDu SinoStandards Bio-Tech Co.,Ltd. ， | 028-83243028 19136088901 | sinostandards@163.com | China | 4979 | 58 |
| Yancheng Tongming Biotechnology Co., Ltd. | 15195160625 | 2863565288@qq.com | China | 5178 | 58 |
| LGC Science (Shanghai) Ltd. | 17717235263 | offer.de@lgcgroup.com | China | 19036 | 58 |
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