Furo[2,3-c]pyridine-5-carboxylic acid (9CI)
![Furo[2,3-c]pyridine-5-carboxylic acid (9CI) Structure](CAS/GIF/478148-62-8.gif)
- CAS No.
- 478148-62-8
- Chemical Name:
- Furo[2,3-c]pyridine-5-carboxylic acid (9CI)
- Synonyms
- Furo[2,3-c]pyridine-5-carboxylic acid (9CI)
- CBNumber:
- CB71048198
- Molecular Formula:
- C8H5NO3
- Molecular Weight:
- 163.13
- MDL Number:
- MFCD18255510
- MOL File:
- 478148-62-8.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405 |
Furo[2,3-c]pyridine-5-carboxylic acid (9CI) price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 119205 | Furo[2,3-c]pyridine-5-carboxylic acid | 478148-62-8 | 250.00mg | $429 | 2026-05-18 | Buy |
| Matrix Scientific | 119205 | Furo[2,3-c]pyridine-5-carboxylic acid | 478148-62-8 | 1.00g | $1072 | 2026-05-18 | Buy |
| Synthonix | F47727 | Furo[2,3-c]pyridine-5-carboxylic acid 95+% | 478148-62-8 | 100mg | $90 | 2026-05-06 | Buy |
| Synthonix | F47727 | Furo[2,3-c]pyridine-5-carboxylic acid 95+% | 478148-62-8 | 250mg | $170 | 2026-05-06 | Buy |
| Synthonix | F47727 | Furo[2,3-c]pyridine-5-carboxylic acid 95+% | 478148-62-8 | 1g | $430 | 2026-05-06 | Buy |
Furo[2,3-c]pyridine-5-carboxylic acid (9CI) Chemical Properties, Uses, Production
Synthesis
![Furo[2,3-c]pyridine-5-carboxaldehyde (9CI)](/CAS/GIF/478148-61-7.gif)
478148-61-7
![Furo[2,3-c]pyridine-5-carboxylic acid (9CI)](/CAS/GIF/478148-62-8.gif)
478148-62-8
The general procedure for the synthesis of furo[2,3-c]pyridine-5-carboxylic acid from furo[2,3-c]pyridine-5-carboxaldehyde was as follows: furo[2,3-c]pyridine-5-carboxaldehyde (850 mg, 5.8 mmol) was dissolved in 10 mL of dimethyl sulfoxide (DMSO). To this solution was added a 3 mL aqueous solution of potassium dihydrogen phosphate (KH2PO4, 221 mg, 1.6 mmol) followed by a 7 mL aqueous solution of sodium chlorite (NaClO2, 920 mg, 8.2 mmol). The reaction mixture was stirred for 3 h at room temperature. After completion of the reaction, the reaction mixture was diluted with 25 mL of water, the pH was adjusted to 10 with 2 N sodium hydroxide (NaOH) solution, and then extracted with ether (3 x 20 mL). The combined ether layers were discarded. The aqueous layer was adjusted to pH 3.5 with 10% aqueous hydrochloric acid (HCl) solution and then extracted with 10% methanol/dichloromethane (MeOH/CH2Cl2, 13 × 10 mL). The combined organic layers were dried with anhydrous sodium sulfate (Na2SO4), filtered and concentrated in vacuum to give a light-colored oil. Residual DMSO was removed at room temperature under a stream of nitrogen (N2) to give a white paste. The paste was dissolved in methanol (MeOH) and concentrated to dryness. The white solid was washed with ether and dried to give the crude furano[2,3-c]pyridine-5-carboxylic acid (94% yield). The compound with molecular formula C8H5NO3 was obtained by mass spectrometry (ESI) analysis with a mass-to-charge ratio (m/z) of 162.8 (M-H)-.
References
[1] Patent: US2003/153595, 2003, A1
[2] Patent: US2003/45540, 2003, A1
[3] Patent: WO2004/52894, 2004, A1. Location in patent: Page 36
[4] Journal of Medicinal Chemistry, 2006, vol. 49, # 14, p. 4425 - 4436
Furo[2,3-c]pyridine-5-carboxylic acid (9CI) Preparation Products And Raw materials
Raw materials
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Preparation Products
Furo[2,3-c]pyridine-5-carboxylic acid (9CI) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| China DongFan Chemical Co.,LTD | 86-0571-85151182 | China | 5681 | 66 | |
| Wuhan Luohua Medical Technology Co.,Ltd. | 13477084141; 13477084141 | sales@luohuapharm.com | China | 468 | 60 |
| QINGDAO CARELONGPHARMATECH CO.,LTD | 053288191853 13061484198 | sales@carelongchem.com | China | 455 | 57 |
| Wuhan ariel chemical Co., LTD. | 18986259541 18986259541 | sales@3stc.com | China | 3828 | 58 |
| Shanghai T&W Pharmaceutical Co., Ltd. | +86 21 61551611 | China | 9874 | 58 | |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| Wuhan Kaymke Chemical Co., Ltd., | 027-87342388 18086026008 | sales@kaymke.com | China | 3537 | 55 |
| Wuxi Zhangkun Biochemical Technology Co., Ltd. | +86 0510-85629785 | China | 2321 | 58 |
View Latest Price from Furo[2,3-c]pyridine-5-carboxylic acid (9CI) manufacturers
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![Furo[2,3-c]pyridine-5-carboxylic acid (9CI) pictures](https://img.chemicalbook.com/ProductImageEN/2020-2/Small/3dd80994-4fe2-4426-897d-362012f4c5b3.jpg) |
2020-02-21 | Furo[2,3-c]pyridine-5-carboxylic acid (9CI)
478148-62-8
|
$3.00 | 1KG | 98% | 200KG | Career Henan Chemical Co |
-
- Furo[2,3-c]pyridine-5-carboxylic acid (9CI)
478148-62-8
- $3.00
- 98%
- Career Henan Chemical Co
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