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ChemicalBook >> CAS DataBase List >>Benzenesulfonamide, 4-[[7'-[(1R,2S)-2-hydroxy-2-methylcyclopentyl]-6'-oxospiro[cyclopropane-1,5'-[5H]pyrrolo[2,3-d]pyrimidine]-2'(7'H)-yl]amino]-N-(3-methyl-3-azetidinyl)-, rel-

Benzenesulfonamide, 4-[[7'-[(1R,2S)-2-hydroxy-2-methylcyclopentyl]-6'-oxospiro[cyclopropane-1,5'-[5H]pyrrolo[2,3-d]pyrimidine]-2'(7'H)-yl]amino]-N-(3-methyl-3-azetidinyl)-, rel-

Benzenesulfonamide, 4-[[7'-[(1R,2S)-2-hydroxy-2-methylcyclopentyl]-6'-oxospiro[cyclopropane-1,5'-[5H]pyrrolo[2,3-d]pyrimidine]-2'(7'H)-yl]amino]-N-(3-methyl-3-azetidinyl)-, rel- Structure
Benzenesulfonamide, 4-[[7'-[(1R,2S)-2-hydroxy-2-methylcyclopentyl]-6'-oxospiro[cyclopropane-1,5'-[5H]pyrrolo[2,3-d]pyrimidine]-2'(7'H)-yl]amino]-N-(3-methyl-3-azetidinyl)-, rel- structure
CAS No.
2498658-13-0
Chemical Name:
Benzenesulfonamide, 4-[[7'-[(1R,2S)-2-hydroxy-2-methylcyclopentyl]-6'-oxospiro[cyclopropane-1,5'-[5H]pyrrolo[2,3-d]pyrimidine]-2'(7'H)-yl]amino]-N-(3-methyl-3-azetidinyl)-, rel-
Synonyms
CDK2-IN-7;Benzenesulfonamide, 4-[[7'-[(1R,2S)-2-hydroxy-2-methylcyclopentyl]-6'-oxospiro[cyclopropane-1,5'-[5H]pyrrolo[2,3-d]pyrimidine]-2'(7'H)-yl]amino]-N-(3-methyl-3-azetidinyl)-, rel-
CBNumber:
CB710659688
Molecular Formula:
C24H30N6O4S
Molecular Weight:
498.6
MDL Number:
MOL File:
2498658-13-0.mol
MSDS File:
SDS
Last updated:2025-04-18 09:52:35
Request For Quotation

Benzenesulfonamide, 4-[[7'-[(1R,2S)-2-hydroxy-2-methylcyclopentyl]-6'-oxospiro[cyclopropane-1,5'-[5H]pyrrolo[2,3-d]pyrimidine]-2'(7'H)-yl]amino]-N-(3-methyl-3-azetidinyl)-, rel- Properties

Boiling point 782.0±70.0 °C(Predicted)
Density 1.50±0.1 g/cm3(Predicted)
pka 8.23±0.20(Predicted)

Benzenesulfonamide, 4-[[7'-[(1R,2S)-2-hydroxy-2-methylcyclopentyl]-6'-oxospiro[cyclopropane-1,5'-[5H]pyrrolo[2,3-d]pyrimidine]-2'(7'H)-yl]amino]-N-(3-methyl-3-azetidinyl)-, rel- Chemical Properties, Uses, Production

Uses

CDK2-IN-7 is a CDK2 inhibitor for researching cancer (IC50 < 50 nM).

IC 50

CDK2/cyclinE: 50 nM (IC50)

References

[1] Sabnis RW. Sulfonylamide Compounds as CDK2 Inhibitors for Treating Cancer. ACS Med Chem Lett. 2021 Sep 13;12(10):1528-1529. DOI:10.1021/acsmedchemlett.1c00471

Benzenesulfonamide, 4-[[7'-[(1R,2S)-2-hydroxy-2-methylcyclopentyl]-6'-oxospiro[cyclopropane-1,5'-[5H]pyrrolo[2,3-d]pyrimidine]-2'(7'H)-yl]amino]-N-(3-methyl-3-azetidinyl)-, rel- Preparation Products And Raw materials

Raw materials

Preparation Products

Benzenesulfonamide, 4-[[7'-[(1R,2S)-2-hydroxy-2-methylcyclopentyl]-6'-oxospiro[cyclopropane-1,5'-[5H]pyrrolo[2,3-d]pyrimidine]-2'(7'H)-yl]amino]-N-(3-methyl-3-azetidinyl)-, rel- Suppliers

Global Suppliers ( 2)
Supplier Tel Email Country ProdList Advantage
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Supplier Advantage
BOC Sciences 58
TargetMol Chemicals Inc. 58

2498658-13-0 (Benzenesulfonamide, 4-[[7'-[(1R,2S)-2-hydroxy-2-methylcyclopentyl]-6'-oxospiro[cyclopropane-1,5'-[5H]pyrrolo[2,3-d]pyrimidine]-2'(7'H)-yl]amino]-N-(3-methyl-3-azetidinyl)-, rel-) Related Search:

N-(5-(difluoromethoxy)-1H-pyrazol-3-yl)-1-((tetrahydro-2H-pyran-4-yl)methyl)-1H-pyrazolo[3,4-b]pyrazin-6-amine CDK12-CCNK HETERODIMER Protein, HUMAN (SF9) CDK3-CCNE1 HETERODIMER Protein, HUMAN (SF9) OTS964 hydrochloride DRB
Roscovitine

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Benzenesulfonamide, 4-[[7'-[(1R,2S)-2-hydroxy-2-methylcyclopentyl]-6'-oxospiro[cyclopropane-1,5'-[5H]pyrrolo[2,3-d]pyrimidine]-2'(7'H)-yl]amino]-N-(3-methyl-3-azetidinyl)-, rel- CDK2-IN-7 2498658-13-0